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NF-κB
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN12011 | Sulfasalazine | 599-79-1 | Sulfasalazine is a potent and specific NF-B inhibitor and also inhibits system Xsubcsub and induces ferroptosis. |
| CSN16392 | Sodium Salicylate | 54-21-7 | Sodium Salicylate is anti-inflammatory drugs which can inhibit the activation of NF-kappa B. |
| CSN19187 | SC75741 | 913822-46-5 | SC75741 is a novel NF-kappaB inhibitor. |
| CSN18699 | Parthenolide | 20554-84-1 | Parthenolide is a sesquiterpene lactone from the plant feverfew (T. parthenium) with multiple biological functions. Parthenolide inhibits the growth of the promastigote form of L. amazonensis with IC50 of 3.6 gmL, induces apoptosis in cancer cells and blocks inflammation by inhibiting signaling through NF-B. |
| CSN20622 | NIK Inhibitor C33 | 1451079-18-7 | NIK inhibitor C33 is a high-selective inhibitor of tricyclic NF-B inducing kinase (NIK) over PI3K. |
| CSN20621 | NIK Inhibitor C32 | 1555655-78-1 | NIK inhibitor C32 is a high-selective inhibitor of tricyclic NF-B inducing kinase (NIK) over PI3K. |
| CSN12507 | Lipoic acid | 1200-22-2 | Lipoic Acid can inhibit TNF-alpha-induced NF-kappaB activation. |
| CSN16019 | JSH-23 | 749886-87-1 | JSH-23 is an inhibitor of NF-B transcriptional activity with IC50 of 7.1 M in RAW 264.7 cell line. |
| CSN21426 | GSK963 | 2049868-46-2 | GSK963 inhibits RIP1-dependent cell death with an IC50 of between 1 and 4nM in human and murine cells. |
| CSN23601 | Ethyl Caffeate | 102-37-4 | Ethyl caffeate shows suppressesion of NF-B activation and its downstream inflammatory mediators. It can be found in bidens pilosa. |
| CSN21353 | Edasalonexent | 1204317-86-1 | Edasalonexent is an orally bioavailable NF-B inhibitor. |
| CSN10802 | Diethyl maleate | 141-05-9 | Diethylmaleate is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NFkB. |
| CSN18398 | Didox | 69839-83-4 | Didox can prevent LPS-induced NF-KB activation and translocation of NF-kappa beta p65 subunits. |
| CSN10751 | Dauricine | 524-17-4 | Dauricine is a plant metabolite, chemically classified as a phenol, an aromatic ether, and an isoquinoline alkaloid. |
| CSN15792 | CID-2858522 | 758679-97-9 | CID-2858522 selectively inhibits the NF-B pathway (IC50 0.1 M for PMA-stimulated IL-8 production) induced by PKC, operating downstream of PKC but upstream of IKKbeta, without inhibiting other NF-kappaB activation pathways. |
| CSN10538 | Caffeic acid phenethyl ester | 104594-70-9 | Caffeic acid phenethyl ester, a natural product isolated and purified from the barks of Cinnamomum cassia Presl, is a potent and specific inhibitor of NF-B activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities. |
| CSN10538 | Caffeic acid phenethyl ester | 104594-70-9 | Caffeic acid phenethyl ester, a natural product isolated and purified from the barks of Cinnamomum cassia Presl, is a potent and specific inhibitor of NF-B activation, and also displays antioxidant, immunomodulatory and antiinflammatory activities. |
| CSN22711 | Bengamide B | 104947-69-5 | Bengamide B is a potent inhibitor of NF-κB activation with IC50 of 85 nM. |
| CSN19420 | Andrographolide | 5508-58-7 | Andrographolide is a naturally occuring NF-B inhibitor. |
| CSN17995 | Adelmidrol | 1675-66-7 | Adelmidrol is an ethanolamide derivative of azelaic acid with anti-inflammatory properties partly dependent on PPAR, it also markedly reduce pro-inflammatory NF-B pathway. |
| CSN23578 | 4'-Hydroxychalcone | 2657-25-2 | 4-Hydroxychalcone has diverse biological activities including inhibiting TNF-induced NF-B pathway activation and activating BMP signaling. It is found in herbs and spices and tea, is a member of the class of compounds known as retrochalcones. |
| CSN23620 | 4-Aminosalicylic acid | 65-49-6 | 4-Aminosalicylic acid, known as PAS, is an antibacterial agent used to treat tuberculosis. It works by suppressing NF-B and scavenging free radicals. |
| CSN13425 | (-)-DHMEQ | 287194-40-5 | (-)-DHMEQ, the eutomer of DHMEQ , is a developed NF-kB inhibitor with stronger activity than ()-DHMEQ., inhibits nuclear factor kB activation with IC50 value of 20 ugmL. |
| CSN19066 | (+)-DHMEQ | 287194-41-6 | ()-DHMEQ, the distomer of DHMEQ, is an inhibitor of NF-B. |
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