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NADPH Oxidase

NADPH Oxidase

Cat. No. Product Name CAS No. Information
CSN21151 VAS2870 722456-31-7 VAS2870 is a specific and effect NADPH oxidase inhibitor with IC50 value of 106 M against NOX activity in human neutrophil lysates
CSN21291 ML171   6631-94-3 ML171 is a novel and selective NOX1 inhibitor with IC50 value of 0.25 M for blocking NOX1-dependent ROS generation in a HEK293-NOX1 recombinant cell system.
CSN18816 GSK2795039 1415925-18-6 GSK2795039 is a small molecule NADPH Oxidase 2 Inhibitor.
CSN22127 GLX351322 835598-94-2 GLX351322 is an inhibitor of NADPH oxidase 4 inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 M
CSN13646 GKT-137831 1218942-37-0 GKT137831 is a specific dual Nox1Nox4 inhibitor with Ki of 14040 nM and 11030 nM and a potent inhibitor of fibrosis and hepatocyte apoptosis
CSN25216 Fluorofenidone 848353-85-5 Fluorofenidone attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and ECM deposition via the PI3K/Akt signalling pathway, suggesting AKF-PD is a potential novel therapeutic agent against renal fibrosis.
CSN20206 BJ-1301 1287234-48-3 BJ-1301 is a promising candidate for the management of tumor agiongenesis and growth via inhibition of RTK and NADPH oxidase activities
CSN25329 APX-115 free base 1270084-92-8 APX-115 free base (Ewha-18278 free base) is a potent, orally active pan NADPH oxidase (Nox) inhibitor with Ki values of 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2 and Nox4, respectively.
CSN12681 Apocynin   498-02-2 Apocynin is potent and selective NADPH-oxidase inhibitor with IC50 value of 10 M
CSN14626 8-Epideoxyloganic Acid 88668-99-9 8-Epideoxyloganic acid, a natural product isolated and purified from the herb of Lamiophlomis rotata, with anti-inflammatory activity, weak antinociceptive activity and bioactivities of analgesia, homeostasis, has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibly through modulation of NOX activity and/or the radical scavenging effect, and beta2 integrin expression in leucocytes.
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