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mTOR

mTOR

Cat. No. Product Name CAS No. Information
CSN16829 WYE-354 1062169-56-5 WYE-354 is a potent specific and ATP-competitive inhibitor of mTOR with IC50 of 5 nM blocks mTORC1P-S6K T389 and mTORC2P-AKT S473 not P-AKT T308 selective for mTOR than PI3K 100-fold and PI3K 500-fold
CSN12047 Temsirolimus 162635-04-3 Temsirolimus directly inhibits mTOR kinase activity with IC50 values of 176 015 M
CSN17210 Salidroside   10338-51-9 Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola crenulata.
CSN16385 Rapamycin   53123-88-9 Rapamycin is a specific mTOR inhibitor with IC50 of 0.1 nM.
CSN11574 Nordihydroguaiaretic Acid 500-38-9 Nordihydroguaiaretic Acid is a naturally occuring mTORC1 inhibitor
CSN27361 Niclosamide olamine 1420-04-8 Niclosamide olamine is an anthelmintic that disrupts mitochondrial metabolism in parasitic worms and animal models. Niclosamide olamine inhibits STAT3 (IC50 = 0.25 μM) and stimulates autophagy by reversibly inhibiting mammalian target of Rapamycin complex 1 (mTORC1) signaling.
CSN19147 LY303511 HCl 2070014-90-1 LY303511 HCl is an analogue of LY294002 which can inhibit mTOR-dependent phosphorylation of S6K but not PI3K-dependent phosphorylation of Akt It also blocks voltage-gated potassium Kv channels with IC50 value of 646 M
CSN25185 L-Leucine 61-90-5 Leucine is one of nine essential amino acids in humans which is important for protein synthesis and many metabolic functions. It contributes to regulation of blood-sugar levels growth and repair of muscle and bone tissue growth hormone production and wound healing.
CSN16716 Everolimus   159351-69-6 Everolimus is a mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM.
CSN16716 Everolimus   159351-69-6 Everolimus is a mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM.
CSN15905 ETP-46464 1345675-02-6 ETP-46464 is a cell-permeable quinoline-containing heterotricyclic compound that acts as a potent inhibitor against mTOR ATR DNA-PK PI 3-K and ATM IC50 06 14 36 170 and 545 nM respectively
CSN18073 AP1903 195514-63-7 AP1903 is a homodimer binding to FKBP and elicites potent and dosedependent apoptotic death of engineered cell line HT1080 in culture with an EC50 of 01 nM
CSN12442 (+)-Usniacin 7562-61-0 ()-Usniacin, a naturally occurring dibenzofuran derivative isolated and purified from the Usnea diffracta Vain. with antitumoral, antiviral, antibiotic, acaricidal, antipyretic, analgesic, antioxidative and anti-inflammatory activities.
CSN27773 mTOR inhibitor-1   468747-17-3
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