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Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11.


Cat. No. Product Name CAS No. Information
CSN27841 PFM01   1558598-41-6 PFM 01 is a MRE11 endonuclease inhibitor which can prevent double-stranded break resection. It enhances NHEJ and reduces homologous recombination.
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