Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11.
|Cat. No.||Product Name||CAS No.||Information|
|CSN27841||PFM01||1558598-41-6||PFM 01 is a MRE11 endonuclease inhibitor which can prevent double-stranded break resection. It enhances NHEJ and reduces homologous recombination.|