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MMP

MMP

Cat. No. Product Name CAS No. Information
CSN19037 TAPI-2 187034-31-7 TAPI-2 is a broad-spectrum inhibitor of matrix metalloprotease MMP tumour necrosis factor-converting enzyme TACE and a disintegrin and metalloproteinase ADAM with an IC50 of 2010 M for MMP
CSN18802 TAPI-1(Random Configuration) 171235-71-5 TAPI-1 is an ADAM17TACE inhibitor which blocks shedding of cytokine receptors
CSN17979 TAPI-1 163847-77-6 TAPI-1 is a specific TACE TNF--converting enzyme inhibitor
CSN20402 TACE Inhibitor C3 1219812-22-2 TACE inhibitor C3 is a prodrug of hydantoin based TNF- converting enzyme TACE inhibitor
CSN16623 SB-3CT 292605-14-2 SB-3CT is a potent competitive and non-selective MMP-2 and MMP-9 inhibitor with Ki values of 139 and 600 nM respectively
CSN16901 Salvianolic Acid A 96574-01-5 Salvianolic acid A, a natural product isolated and purified from the root of Salvia miltiorrhiza Bge. with antioxidant and protective activity, significantly improves glucose metabolism and inhibit oxidative injury as well as protect against impaired vascular responsiveness in STZ-induced diabetic rats, inhibits platelet activation via the inhibition of PI3K, and attenuates arterial thrombus formation in vivo, suggesting that it may be developed as a therapeutic agent for the prevention of thrombotic disorders. Salvianolic acid A is also a matrix metalloproteinase-9 inhibitor, can prevents cardiac remodeling in spontaneously hypertensive rats, and inhibits PDGF-BB-activated HSC proliferation, partially through apoptosis induction while exerting no direct cytotoxicity on primary hepatocytes and HSC-T6 cells under experimental concentrations.
CSN21234 S-methyl-KE-298 143584-75-2 S-methyl-KE-298 is an active metabolite of KE-298. KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells.
CSN21340 S 3304   203640-27-1 S 3304 is a novel MMP inhibitor
CSN22013 Prinomastat 192329-42-3 Prinomastat is a spectrum inhibitor of MMP with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9 respectively.
CSN16584 NSC 405020   7497-07-6 NSC 405020 is a non-catalytic Membrane type-1 MMP inhibitor with IC50 100 M
CSN15948 Morroniside 25406-64-8 Morroniside is a naturally occuring iridoid which can regulate hair growth and cycle transition via activation of the Wnt-catenin signaling pathway.
CSN19679 MMP13-In-1 935759-55-0 MMP13-In-1 is a selective Matrix Metalloproteinase MMP-13 inhibitors
CSN12943 Marimastat 154039-60-8 Marimastat is a competitive and broad-spectrum MMP inhibitor with IC50 values of 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7, respectively.
CSN14005 Isoginkgetin 548-19-6 Isoginkgetin is a MMP-9 inhibitor isolated and purified from the leaves of Ginkgo biloba L also a Pre-mRNA Splicing inhibitor with IC 50 of 30 M
CSN11187 GM6001     142880-36-2 GM6001 is a broad spectrum MMPs inhibitor for MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-14, and MMP-26 with Ki of 0.4 nM, 0.5 nM, 27 nM, 3.7 nM, 0.1 nM, 0.2 nM, 3.6 nM, 13.4 nM, 0.36 nM, respectively.
CSN19851 GI 254023X 260264-93-5 GI 254023X is a potent and selective ADAM10 metalloproteinase inhibitor
CSN18069 CTS-1027 193022-04-7 CTS-1027 is a potent small molecule inhibitor of MMPs (IC500.4 nM0.6 nM for MMP2MMP13), displaying 1,000 fold selectivity over MMP1.
CSN17191 CL-82198 307002-71-7 CL-82198 is a selective inhibitor of MMP-13
CSN19813 Aderbasib 791828-58-5 Aderbasib is a sheddase inhibitor, is also an orally bioavailable inhibitor of the ADAM (A disintegrin and metalloprotease) family of multifunctional membrane-bound proteins with potential antineoplastic activity.
CSN20301 ADAMTS Inhibitor C7 1607004-34-1 ADAMTS inhibitor C7 is an inhibitor of aggrecanase 1 and 2 (ADAMTS-4 and ADAMTS-5) had good oral pharmacokinetics in rats and showed efficacy in a rat chemical model of os-teoarthritis.
CSN19878 20(R)-Ginsenoside Rh2   112246-15-8 20(R)-Ginsenoside Rh2 has anticancer effects and can increase inchoate apoptotic rate, reduce apoptotic rate significantly, enhance the activity of caspase-3 and induces apoptosis in human lung adenocarcinoma A549 cells. It is a natural product isolated and purified from the roots of Panax ginseng C. A. Mey..
CSN11720 Pimaric Acid 127-27-5
CSN15653 Ginsenoside CK 39262-14-1
CSN23111 SD 2590 HCl 226395-93-3
CSN23138 T 26c Disodium Salt 869298-22-6
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