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MLK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN15761 | URMC-099 | 1229582-33-5 | URMC-099 is an orally bioavailable brain penetrant inhibitor of Mixed Lineage Kinase 3 MLK3 with IC50 of 14 nM It inhibits LPS-induced TNF release in microglial cells HIV-1 Tat-induced release of cytokines in human monocytes and up-regulation of phospho-JNK in Tat-injected brains of mice |
| CSN26707 | MLK-IN-1 | 1627729-62-7 | MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1[1]. |
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