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MLK

MLK

Cat. No. Product Name CAS No. Information
CSN15761 URMC-099 1229582-33-5 URMC-099 is an orally bioavailable brain penetrant inhibitor of Mixed Lineage Kinase 3 MLK3 with IC50 of 14 nM It inhibits LPS-induced TNF release in microglial cells HIV-1 Tat-induced release of cytokines in human monocytes and up-regulation of phospho-JNK in Tat-injected brains of mice
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