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MLK

MLK

Cat. No. Product Name CAS No. Information
CSN15761 URMC-099 1229582-33-5 URMC-099 is an orally bioavailable brain penetrant inhibitor of Mixed Lineage Kinase 3 MLK3 with IC50 of 14 nM It inhibits LPS-induced TNF release in microglial cells HIV-1 Tat-induced release of cytokines in human monocytes and up-regulation of phospho-JNK in Tat-injected brains of mice
CSN26707 MLK-IN-1 1627729-62-7 MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor, compound 68, extracted from patent US20140256733A1[1].
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