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mGluR

mGluR

Cat. No. Product Name CAS No. Information
CSN23892 VU6012962 2313526-86-0 VU6012962 is a CNS-penetrant metabotropic glutamate receptor 7 (mGlu7) negative allosteric modulator (NAM) with an IC50 of 347 nM.
CSN12115 Topiramate   97240-79-4 Topiramate is a selective GluK1 kainate receptors (GluR5) antagonist with IC50 value of 0.46 M which can act as a positive allosteric modulator of GABAA receptor-mediated currents, inhibit Nav channels and L-type Ca2 channels.
CSN23124 Spaglumic Acid 3106-85-2 Spaglumic Acid is a neuropeptide found in millimolar concentrations in brain.
CSN23187 VU 29 890764-36-0 Potent positive allosteric modulator of mGlu5 receptors
CSN22913 MMPEP   823198-78-3 MMPEP is both a selective non-competitive mGlu5 receptor antagonist with IC50 value of 36 nM and a mGlu4 receptor positive allosteric modulator.
CSN18024 LY354740 176199-48-7 LY354740 is a highly potent efficacious and selective group II mGlu23 receptor agonist produces 90 suppression of forskolin-stimulated cAMP formation with an EC50 of 51 03 nM
CSN11296 L-Glutamic Acid Monosodium 142-47-2 L-Glutamic Acid Monosodium is an excitatory amino acid neurotransmitter as an agonist at GluR and NMDA receptor.
CSN27529 L-Cysteinesulfinic acid monohydrate 207121-48-0 L-Cysteinesulfinic acid monohydrate is a potent agonist at several rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92, 4.6, 3.9, 2.7, 4.0, and 3.94 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively.
CSN23016 H-Ser(PO3H2)-OH   407-41-0 H-SerPO3H2-OH is both a Group III metabotropic glutamate receptor mGluR4 mGluR7 and mGluR8 agonist and a competitive NMDA antagonist
CSN24484 (S)-4CPG 134052-73-6 (S)-4CPG is a selective competitive group I mGlu antagonist.
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