Proto-oncogene tyrosine-protein kinase MER is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the TYRO3/AXL/MER (TAM) receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain.
|Cat. No.||Product Name||CAS No.||Information|
|CSN28428||XL092||2367004-54-2||XL-092 is an ATP-competitive inhibitor of multiple receptor tyrosine kinases including MET, VEGFR2, AXL and MER, with IC50 values of 15, 1.6, 3.4, and 7.2 nM, respectively, in cell-based assays.|
|CSN22060||MRX-2843||1429882-07-4||MRX-2843 is an orally available small-molecule inhibitor of both MERTK and FLT3.|