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MDM2
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN18271 | SJ-172550 | 431979-47-4 | SJ-172550 is a small molecule inhibitor of MDMX and competes for the wild type p53 peptide binding to MDMX with an EC50 of 5 M |
| CSN19741 | PK11195 | 85532-75-8 | PK11195 is a 2Phenylindolylglyoxylyldipeptide Murine Double Minute2 MDM2Translocator Protein TSPOHuman Constitutive Androstane Receptor hCAR Inhibitor and is potentially useful for the Treatment of Gliomas |
| CSN20477 | NSC 66811 | 6964-62-1 | NSC 66811 is a potent MDM2 inhibitor with Ki value of 120 nM which can disrupt MDM2-p53 interaction and activate p53 function |
| CSN17369 | NSC 59984 | 803647-40-7 | NSC 59984 is a reactivator of p53 which targets various mutant p53 to restore wild-type p53 pathway via the activation of p73 in cancer cells It could induce p53 mutant protein degradation via MDM2-mediated ubiquitination |
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