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Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN28456 | PROTAC Mcl1 degrader-1 | 2163793-38-0 | PROTAC Mcl1 degrader-1 (compound C3) is a PROTAC targeting on Bcl-2 and Mcl-1 with DC50 values of 3μM and 0.7μM, respectively. |
| CSN28452 | PROTAC Bcl2 degrader-1 | 2378801-85-3 | PROTAC Bcl2 degrader-1 (Compound C5) is a PROTAC targeting on Bcl-2 and Mcl-1 with DC50 values of 3μM and 0.7μM, respectively. |
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