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LRRK2
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN24806 | PF-06454589 | 1527473-30-8 | PF-06454589 is a potent and selective LRRK2 inhibitor. |
| CSN15765 | PF-06447475 | 1527473-33-1 | PF-06447475 is a brain-penetrant potent and selective LRRK2 inhibitor with IC50 values of 3 nM possessing neuroprotective activity |
| CSN28447 | 6-((2,5-Dimethoxyphenyl)thio)-3-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazine | 1622291-81-9 | PF-06371900 is a selective LRRK2 inhibitor with IC50 value of 64nM. |
| CSN19704 | MLi-2 | 1627091-47-7 | MLi-2 is a highly potent and selective LRRK2 kinase inhibitor with central nervous system activity |
| CSN15891 | LRRK2-IN-1 | 1234480-84-2 | LRRK2-IN-1 is a potent and selective LRRK2 inhibitor with IC50 values of 6 and 13 nM for G2019S mutant and wild-type LRRK2 respectively |
| CSN17129 | JH-II-127 | 1700693-08-8 | JH-II-127 is a brain-penetrant potent and selective LRRK2 inhibitor with IC50 values of 22 66 and 477 nM for G2019S-mutant wild-type and A2016T-mutant LRRK2 respectively |
| CSN17279 | HG-10-102-01 | 1351758-81-0 | HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2 IC50233 nM and the G2019S mutant IC5032 nM |
| CSN15754 | GSK2578215A | 1285515-21-0 | GSK2578215A is a brain-penetrant potent and selective LRRK2 inhibitor with IC50 values of 89 and 101 nM for LRRK2G2019S mutant and wild-type LRRK2 respectively |
| CSN15912 | GNE0877 | 1374828-69-9 | GNE0877 is a highly potent selective and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 LRRK2 small molecule inhibitor with an IC50 of 3 nM |
| CSN17916 | GNE-9605 | 1536200-31-3 | GNE-9605 is a selective and potent LRRK2 with IC50 value of 187 nM |
| CSN18902 | GNE-7915 tosylate | 2070015-00-6 | GNE-7915 tosylate is a potent selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 9 nM |
| CSN17181 | GNE-7915 | 1351761-44-8 | GNE-7915 is a brain-penetrant potent and selective LRRK2 inhibitor with IC50 value of 9 nM |
| CSN16309 | CZC-54252 | 1191911-27-9 | CZC-54252 is a potent LRRK2 inhibitor with IC50 values of 128 nM and 185 nM for wild-type and G2019S mutant LRRK2 respecitively possessing neuroprotective effect |
| CSN17277 | CZC-25146 | 1191911-26-8 | CZC-25146 is a potent LRRK2 inhibitor with IC50 values of 476 and 687 nM for for wild-type and G2019S mutant LRRK2 respectively It also inhibits PLK4 GAK TNK1 CAMKK2 and PIP4K2 |
| CSN17694 | CZC-25146 hydrochloride | 1330003-04-7 | CZC-25146 HCl is a potent, selective and metabolically stable LRRK2 inhibitor with IC50 of 4.76 nM/6.87 nM for wild type LRRK2 and G2019S LRRK2 respectively. |
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