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Lipase

Lipase

Cat. No. Product Name CAS No. Information
CSN19410 Tanshinone IIA   568-72-9 Tanshinone IIA is a naturally occuring cardioprotective agent which can inhibit NF-κB and AP-1 DNA binding and display antioxidant and anti-inflammatory properties. Tanshinone IIA showed inhibitory effect on PL(pro) with IC50 value of 1.6μM and less inhibitory effect on 3CLpro with IC50 value of 89.1μM.
CSN25327 RHC 80267 83654-05-1 RHC 80267 is a diacylglycerol (DAG) lipase inhibitor and an important second messenger in signal transduction pathways.
CSN16507 Orlistat   96829-58-2 Orlistat is an approved reversible general lipase inhibitor with IC50 of 122 ngmL, used to treat obesity.
CSN26493 MAGL-IN-1 2324160-91-8 MAGL-IN-1 is a potent and selective monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 80 nM.
CSN15416 Leachianone G 152464-78-3 Leachianone G, a natural product isolated and purified from the roots of Sophora flavescens Ait., shows inhibitory activities against pancreatic lipase, and may be used as drug candidate to control obesity. Leachianone G exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays, and shows potent antiviral activity (IC(50) 1.6 mgmL).
CSN25292 Ibrolipim 133208-93-2 Ibrolipim is a Lipoprotein lipase activator.
CSN37975 HSL-IN-1 2095156-13-9 HSL-IN-1 is a potent and orally active HSL inhibitor with IC50 value of 2nM, which shows a significantly reduced reactive metabolite liability.
CSN50676 5(R)-Hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylheptan-3-one 68622-73-1 Hormone-Sensitive Lipase (LIPE; HSL) Inhibitors Triglyceride Lowering Agents
CSN50680 Methyl trans-5-dodecyl-2-methoxy-7-methyl-2-oxo-2,3,4,5-tetrahydro-1,2lambda5-oxaphosphepine-6-carboxylate 1412439-89-4 Hormone-Sensitive Lipase (LIPE; HSL) Inhibitors Monoacylglycerol Lipase (Rv0183) (Mycobacterium tuberculosis) Inhibitors Triacylglycerol Lipase (lipY) (Mycobacterium tuberculosis) Inhibitors
CSN50682 Methyl (cis)-5-dodecyl-2-methoxy-7-methyl-2-oxo-2,3,4,5-tetrahydro-1,2lambda5-oxaphosphepine-6-carboxylate 2268684-97-3 Diacylglycerol Acyltransferase/Mycolyltransferase Ag85C (Mycobacterium tuberculosis) Inhibitors Hormone-Sensitive Lipase (LIPE; HSL) Inhibitors Monoacylglycerol Lipase (Rv0183) (Mycobacterium tuberculosis) Inhibitors Triacylglycerol Lipase (lipY) (Mycobacterium tuberculosis) Inhibitors
CSN23660 ABX-1431   1446817-84-0 ABX-1431 works as both a cannabinoid receptor agonist and a MAGL inhibitor
CSN34395 SMP-028 914389-14-3
CSN50678 4-(Hydroxymethyl)piperidine-1-carboxylic acid 4-[5-(trifluoromethyl)pyridin-2-yloxy]phenyl ester 548765-46-4
CSN50692 2-Chloro-N-[(6R,7aS)-3-oxo-2-[4-(trifluoromethoxy)phenyl]hexahydro-1H-pyrrolo[1,2-c]imidazol-6-yl]pyridine-3-sulfonamide 1408313-66-5
CSN50694 2-Chloro-N-[(6R,7aS)-3-oxo-2-[4-(trifluoromethoxy)phenyl]hexahydro-1H-pyrrolo[1,2-c]imidazol-6-yl]benzenesulfonamide 1408313-50-7
CSN50688 (3aR,7aS)-5-[4-(2,2,2-Trifluoroethoxy)phenyl]-2-[[2-(trifluoromethoxy)phenyl]sulfonyl]octahydro-4H-pyrrolo[3,4-c]pyridin-4-one 1412906-02-5
CSN50700 (5S,7S,8S)-8-Hydroxy-7-(2,2,2-trifluoroethoxy)-2-[4-(trifluoromethoxy)phenyl]-2-azaspiro[4.5]decan-1-one 1399175-06-4
CSN50711 3-[3-(Benzyloxy)phenyl]-5-ethoxy-1,3,4-oxadiazol-2(3H)-one 328404-08-6
CSN50708 N-[4-(5-Methoxy-2-oxo-2,3-dihydro-1,3,4-oxadiazol-3-yl)phenyl]-5-oxo-5-phenylpentanamide 1027488-51-2
CSN50704 (±)-(5S*,7S*,8R*)-8-Hydroxy-7-(propan-2-yl)-2-[4-(2,2,2-trifluoroethoxy)phenyl]-2-azaspiro[4.5]decan-1-one 1399175-13-3
CSN50707 3-(4-Chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trifluoroethylsulfanyl)-1H-1,2,4-triazole-1-carboxamide 654059-14-0
CSN50710 5-Methoxy-3-[3-(3,3,5,5-tetramethylcyclohexyloxy)phenyl]-1,3,4-oxadiazol-2(3H)-one 328404-14-4
CSN50695 4-Chloro-N-[(6R,7aS)-3-oxo-2-[4-(trifluoromethoxy)phenyl]hexahydro-1H-pyrrolo[1,2-c]imidazol-6-yl]benzamide 1408313-77-8
CSN50689 (3aS,7aR)-2-[(2-Chlorophenyl)sulfonyl]-5-[4-(trifluoromethoxy)phenyl]octahydro-4H-pyrrolo[3,4-c]pyridin-4-one 1412905-85-1
CSN50706 8-(2-Hydroxy-5-methylphenyl)-2-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decan-1-one 1359880-68-4
CSN50705 8-(2-Hydroxypyridin-3-yl)-2-[4-(trifluoromethoxy)phenyl]-2,8-diazaspiro[4.5]decan-1-one 1359880-69-5
CSN50709 N-[3-Chloro-4-(5-methoxy-2-oxo-2,3-dihydro-1,3,4-oxadiazol-3-yl)phenyl]-4-heptylbenzamide 359847-49-7
CSN50702 (±)-(5S*,7S*,8R*)-8-Hydroxy-7-(propan-2-yl)-2-[4-(trifluoromethoxy)phenyl]-2-azaspiro[4.5]decan-1-one 1399174-96-9
CSN50703 (±)-(5S*,7R*,8R*)-8-Hydroxy-7-propyl-2-[4-(trifluoromethoxy)phenyl]-2-azaspiro[4.5]decan-1-one 1399174-95-8
CSN50701 (±)-(5R*,7R*,8R*)-8-Hydroxy-7-(2,2,2-trifluoroethoxy)-2-[4-(trifluoromethoxy)phenyl]-2-azaspiro[4.5]decan-1-one 1399175-02-0
CSN50698 (±)-(5S*,7R*,8R*)-8-Hydroxy-7-propyl-2-[4-(2,2,2-trifluoroethoxy)phenyl]-2-azaspiro[4.5]decan-1-one 1399175-11-1
CSN50687 2-Chloro-N-[(3aR,6aS)-1-oxo-2-[4-(trifluoromethoxy)phenyl]octahydrocyclopenta[c]pyrrol-5-yl]benzenesulfonamide 1412906-36-5
CSN50679 2-[N-(2-Isopropyl-6-methylbenzyl)carbamoyl]-1-methyl-3-oxo-2,3-dihydro-1H-indazole-7-carboxylic acid 787580-42-1
CSN50674 [5-Fluoro-2-[2-oxo-2-[4-[[5-(trifluoromethyl)pyridin-2-yl]oxy]piperidin-1-yl]ethyl]phenyl]boronic acid 2131083-90-2
CSN50690 (3aS,7aR)-2-(Phenylacetyl)-5-[4-(trifluoromethoxy)phenyl]octahydro-4H-pyrrolo[3,4-c]pyridin-4-one 1412905-69-1
CSN50686 Methyl (2R,5R)-5-decyl-2-methoxy-7-methyl-2,3,4,5-tetrahydro-1,2-oxaphosphepine-6-carboxylate 2-oxide 1436581-93-9
CSN50677 4-Hydroxypiperidine-1-carboxylic acid 4-[5-(trifluoromethyl)pyridin-2-yloxy]phenyl ester 548765-62-4
CSN50675 [2-[(4-[[5-(Trifluoromethyl)pyridin-2-yl]oxy]phenyl)methoxy]phenyl]boronic acid 1961237-62-6
CSN50683 [5-Chloro-2-[2-oxo-2-[4-[[5-(trifluoromethyl)pyridin-2-yl]oxy]piperidin-1-yl]ethyl]phenyl]boronic acid 2131083-91-3
CSN50696 2-Fluoro-N-[(6R,7aS)-3-oxo-2-[4-(trifluoromethoxy)phenyl]hexahydro-1H-pyrrolo[1,2-c]imidazol-6-yl]benzenesulfonamide 1408313-65-4
CSN50693 2-Fluoro-N-[(6S,7aS)-3-oxo-2-[4-(trifluoromethoxy)phenyl]hexahydro-1H-pyrrolo[1,2-c]imidazol-6-yl]benzenesulfonamide 1408313-85-8
CSN50699 (±)-(5R*,7R*,8R*)-8-Hydroxy-7-propoxy-2-[4-(trifluoromethoxy)phenyl]-2-azaspiro[4.5]decan-1-one 1399175-10-0
CSN50684 N-[4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-6-[4-(trifluoromethyl)phenoxy]pyridine-3-carboxamide 2095156-06-0
CSN50685 [2-(4-[[5-(Trifluoromethyl)pyridin-2-yl]oxy]benzamido)phenyl]boronic acid 2095155-94-3
CSN50681 Methyl (2R)-2-(hexadecyloxy)-4-methyl-2-oxo-6,7-dihydro-2H-1,3,2lambda5-dioxaphosphepine-5-carboxylate 2225891-71-2
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