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Lipase

Lipase

Cat. No. Product Name CAS No. Information
CSN16272 XEN445 1515856-92-4 XEN445 is a potent and selective endothelial lipase inhibitor with IC50 of 0237 M
CSN16507 Orlistat   96829-58-2 Orlistat is an approved reversible general lipase inhibitor with IC50 of 122 ngmL, used to treat obesity.
CSN15416 Leachianone G 152464-78-3 Leachianone G, a natural product isolated and purified from the roots of Sophora flavescens Ait., shows inhibitory activities against pancreatic lipase, and may be used as drug candidate to control obesity. Leachianone G exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays, and shows potent antiviral activity (IC(50) 1.6 mgmL).
CSN20309 LCL521 1226851-11-1 LCL521 an inhibitor of acid ceramidase shows anticancer actions of lysosomally targeted
CSN20310 LCL521 2HCl 1226759-47-2 LCL521 2HCl, an inhibitor of acid ceramidase, shows anticancer actions of lysosomally targeted.
CSN17769 KML29 1380424-42-9 KML29 is a highly selective and potent MAGL inhibitor with IC50s for 15 43 and 59 nM in mouse rat and human brain proteomes respectively
CSN22871 JZP 361 1680193-80-9 JZP 361 is a potent and selective reversible MAGL inhibitor with IC50 of 46 nM.
CSN13781 JW 642 1416133-89-5 JW 642 is a potent inhibitor of monoacylglycerol lipase MAGL that displays IC50 values of 76 14 and 37 nM for inhibition of MAGL in mouse rat and human brain membranes respectively
CSN22866 JJKK 048 1515855-97-6 JJKK 048 is a potent and selective monoacylglycerol lipase (MAGL) inhibitor with IC50 of 0.4 nM.
CSN16736 Cetilistat   282526-98-1 Cetilistat is a novel pancreatic lipase used to treat obesity
CSN20616 Cannabidivarin 24274-48-4 Cannabidivarin is a non-psychoactive cannabinoid found in Cannabis that activates CB2 cannabinoid receptors as well as the transient receptor potential channels TRPA1, TRPV1, and TRPV2 (EC50s 0.42, 3.6, and 7.3 M, respectively). It is also reported to antagonize TRPM8 (IC50 0.9 M) and to inhibit diacylglycerol lipase (IC50 16.6 M).
CSN15923 Atglistatin 1469924-27-3 Atglistatin is a potent selective and competitive ATGL with IC50 value of 07 M
CSN23660 ABX-1431   1446817-84-0 ABX-1431 works as both a cannabinoid receptor agonist and a MAGL inhibitor
CSN13793 Pristimerin 1258-84-0
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