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JNK

JNK

Cat. No. Product Name CAS No. Information
CSN12230 SP-600125     129-56-6 SP-600125 is a competitive and reversible JNK inhibitor with IC50 values of 40 nM, 40 nM and 90 nM for JNK1, 2 and 3.
CSN23136 SU 3327 40045-50-9 Selective JNK inhibitor
CSN13417 Kaempferol 3-O-Arabinoside 5041-67-8 Kaempferol 3-O-arabinoside is a natural product isolated and purified from the roots of Ligusticum jeholense Nakai et Kitag displaying cytotoxic and high antioxidant activity.
CSN14309 Juglanin 5041-67-8 Juglanin, a natural product isolated and purified from the herbs of Phymatopteris hastate with antioxidant activity, shows protective effects on fructose-induced hepatitis by inhibiting inflammation and apoptosis through TLR4 and JAK2/STAT3 signaling pathways in fructose-fed rats, and can lead to G2/M phase arrest, induce apoptosis as well as autophagy through the ROS/JNK signaling pathway in human breast cancer cells, it may be a promising candidate for development of anti-tumor drugs targeting breast cancer.
CSN15772 JNK Inhibitor IX   312917-14-9 JNK Inhibitor IX can selectively inhibit JNK2 and JNK3 through targeting the ATP binding site with pIC50 of 6.5 and 6.7, respectively.
CSN13968 Isovitexin 38953-85-4 Isovitexin, a natural product isolated and purified from the seeds of Vitex trifolia L., exhibits a potential antioxidant activity, shows a strong antihyperglycemic action, and inhibits -glucosidase in vivo.
CSN18143 IQ-1S Free Acid 23146-22-7 IQ-1S Free Acid is a selective JNK3 inhibitor with IC50 value of 87 nM with less potency against JNK 12 with IC50 values of 390360nM
CSN19488 Ginsenoside Re 52286-59-6 Ginsenoside Re is a panaxatriol saponin that has diverse in vitro and in vivo effects, including vasorelaxant, antioxidant, antihyperlipidemic, and angiogenic actions.
CSN13428 BI-78D3   883065-90-5 BI-78D3 is a selective and competitive JNK inhibitor with IC50 of 280 nM
CSN10356 Auraptene   495-02-3 Auraptene is a natural product isolated and purified from the peel of Poncirus trifoliata with anti-tumor and anti-oxidant activity. Auraptene-mediated activation of JNK may contribute to the production of Aβ by promoting γ-secretase activity.
CSN18465 AS-602801 848344-36-5 AS-602801 is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.
CSN18229 AS-601245 345987-15-7 AS-601245 is an inhibitor of the c-Jun NH2-terminal kinase JNK hJNK1 IC50150nM hJNK2 IC50220nM and hJNK3 IC5070 nM has neuroprotective properties
CSN10317 Anisomycin   22862-76-6 Anisomycin is a naturally occuring antibiotic which can act as a potent activator of stress-activated protein kinases (JNKSAPK) and p38 MAPK, and also can inhibit protein synthesis by blocking translation.
CSN22669 AEG 3482 63735-71-7 AEG 3482 is an inhibitor of c-jun N-terminal kinase (JNK) signaling.
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