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JNK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN23129 | SR-3576 | 1164153-22-3 | SR-3576 is a potent JNK3 inhibitor that is highly selective over p38. |
| CSN17482 | SR-3306 | 1128096-91-2 | SR-3306 is a brain penetrant small molecule JNK inhibitor from the aminopyrimidine class |
| CSN12230 | SP600125 | 129-56-6 | SP-600125 is a competitive and reversible JNK inhibitor with IC50 values of 40 nM, 40 nM and 90 nM for JNK1, 2 and 3. |
| CSN26187 | Sesamolin | 526-07-8 | Sesamolin is a furofuran lignan extracted from sesame seeds, which has beneficial physiological properties such as antioxidant, anti-mutagenic, anti-aging and anti-inflammatory activities. It was also found to inhibit lipid peroxidation in rat liver and kidney. |
| CSN23136 | SU3327 | 40045-50-9 | Selective JNK inhibitor |
| CSN17808 | JNK-IN-8 | 1410880-22-6 | JNK-IN-8 is a potent, selective and irreversible JNK inhibitor with IC50 values of 4.7 nM, 18.7 nM and 1 nM for JNK1, 2 and 3, respectively. |
| CSN17806 | JNK-IN-7 | 1408064-71-0 | JNK-IN-7 is a potent inhibitor for JNK all isoforms with IC50 values of 1.5, 2 and 0.7 nM for JNK1, JNK2 and JNK3, respectively. |
| CSN23162 | JNK Inhibitor VIII | 894804-07-0 | JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively. |
| CSN23162 | JNK Inhibitor VIII | 894804-07-0 | JNK Inhibitor VIII (TCS JNK 6o) is a c-Jun N-terminal kinases (JNK-1, -2, and -3) inhibitor with Ki values of 2 nM, 4 nM, 52 nM, respectively, and has IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively. |
| CSN15772 | TCS JNK 5a | 312917-14-9 | JNK Inhibitor IX can selectively inhibit JNK2 and JNK3 through targeting the ATP binding site with pIC50 of 6.5 and 6.7, respectively. |
| CSN13968 | Isovitexin | 38953-85-4 | Isovitexin, a natural product isolated and purified from the seeds of Vitex trifolia L., exhibits a potential antioxidant activity, shows a strong antihyperglycemic action, and inhibits -glucosidase in vivo. |
| CSN18143 | IQ-1S free acid | 23146-22-7 | IQ-1S Free Acid is a selective JNK3 inhibitor with IC50 value of 87 nM with less potency against JNK 12 with IC50 values of 390360nM |
| CSN22859 | IQ-3 | 312538-03-7 | IQ 3 is a selective JNK3 inhibitor with Kd of 66 nM. |
| CSN22858 | IQ 1S | 1421610-21-0 | IQ 1S is a JNK inhibitor with Kd of 87, 360 and 390 nM for JNK3, JNK2 and JNK1, respectively. |
| CSN17254 | DB07268 | 929007-72-7 | DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM |
| CSN17363 | Tanzisertib | 899805-25-5 | CC-930 is a selective ATP-competitive JNK inhibitor with IC50 values of 61nM, 5nM and 5nM for JNK1, 2 and 3, respectively. |
| CSN16122 | CC-401 | 395104-30-0 | CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase JNK inhibitor with potential antineoplastic activity |
| CSN17322 | CC-401 hydrochloride | 1438391-30-0 | CC-401 HCl is a selective and ATP-competitive JNK inhibitor with Ki values ranging in 25-50 nM |
| CSN13428 | BI-78D3 | 883065-90-5 | BI-78D3 is a selective and competitive JNK inhibitor with IC50 of 280 nM |
| CSN10356 | Auraptene | 495-02-3 | Auraptene is a natural product isolated and purified from the peel of Poncirus trifoliata with anti-tumor and anti-oxidant activity. Auraptene-mediated activation of JNK may contribute to the production of Aβ by promoting γ-secretase activity. |
| CSN18465 | Bentamapimod | 848344-36-5 | AS-602801 is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively. |
| CSN18229 | AS601245 | 345987-15-7 | AS-601245 is an inhibitor of the c-Jun NH2-terminal kinase JNK hJNK1 IC50150nM hJNK2 IC50220nM and hJNK3 IC5070 nM has neuroprotective properties |
| CSN10317 | Anisomycin | 22862-76-6 | Anisomycin is a naturally occuring antibiotic which can act as a potent activator of stress-activated protein kinases (JNKSAPK) and p38 MAPK, and also can inhibit protein synthesis by blocking translation. |
| CSN22669 | AEG3482 | 63735-71-7 | AEG 3482 is an inhibitor of c-jun N-terminal kinase (JNK) signaling. |
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