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JNK

JNK

Cat. No. Product Name CAS No. Information
CSN22565 Vacquinol-1 5428-80-8 Vacquinol-1 is an activator of MKK4-dependent macropinocytotic cell death in glioblastoma cells.
CSN23129 SR 3576 1164153-22-3 SR-3576 is a potent JNK3 inhibitor that is highly selective over p38.
CSN17482 SR-3306 1128096-91-2 SR-3306 is a brain penetrant small molecule JNK inhibitor from the aminopyrimidine class
CSN12230 SP-600125     129-56-6 SP-600125 is a competitive and reversible JNK inhibitor with IC50 values of 40 nM, 40 nM and 90 nM for JNK1, 2 and 3.
CSN23136 SU 3327 40045-50-9 Selective JNK inhibitor
CSN14309 Juglanin 5041-67-8 Juglanin, a natural product isolated and purified from the herbs of Phymatopteris hastate with antioxidant activity, shows protective effects on fructose-induced hepatitis by inhibiting inflammation and apoptosis through TLR4 and JAK2/STAT3 signaling pathways in fructose-fed rats, and can lead to G2/M phase arrest, induce apoptosis as well as autophagy through the ROS/JNK signaling pathway in human breast cancer cells, it may be a promising candidate for development of anti-tumor drugs targeting breast cancer.
CSN17808 JNK-IN-8 1410880-22-6 JNK-IN-8 is a potent, selective and irreversible JNK inhibitor with IC50 values of 4.7 nM, 18.7 nM and 1 nM for JNK1, 2 and 3, respectively.
CSN17806 JNK-IN-7 1408064-71-0 JNK-IN-7 is a potent inhibitor for JNK all isoforms with IC50 values of 1.5, 2 and 0.7 nM for JNK1, JNK2 and JNK3, respectively.
CSN15772 JNK Inhibitor IX   312917-14-9 JNK Inhibitor IX can selectively inhibit JNK2 and JNK3 through targeting the ATP binding site with pIC50 of 6.5 and 6.7, respectively.
CSN22865 JIP-1 (153-163) 438567-88-5 JIP-1 (153-163) is a peptide inhibitor of c-Jun N-terminal kinase.
CSN13968 Isovitexin 38953-85-4 Isovitexin, a natural product isolated and purified from the seeds of Vitex trifolia L., exhibits a potential antioxidant activity, shows a strong antihyperglycemic action, and inhibits -glucosidase in vivo.
CSN18143 IQ-1S Free Acid 23146-22-7 IQ-1S Free Acid is a selective JNK3 inhibitor with IC50 value of 87 nM with less potency against JNK 12 with IC50 values of 390360nM
CSN22859 IQ 3 312538-03-7 IQ 3 is a selective JNK3 inhibitor with Kd of 66 nM.
CSN22858 IQ 1S 1421610-21-0 IQ 1S is a JNK inhibitor with Kd of 87, 360 and 390 nM for JNK3, JNK2 and JNK1, respectively.
CSN17254 DB07268 929007-72-7 DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM
CSN22748 CEP 1347 156177-65-0 CEP 1347 is an inhibitor of c-jun N-terminal kinase (JNK) signaling.
CSN17363 CC-930 899805-25-5 CC-930 is a selective ATP-competitive JNK inhibitor with IC50 values of 61nM, 5nM and 5nM for JNK1, 2 and 3, respectively.
CSN16122 CC-401 395104-30-0 CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase JNK inhibitor with potential antineoplastic activity
CSN17322 CC-401 HCl 1438391-30-0 CC-401 HCl is a selective and ATP-competitive JNK inhibitor with Ki values ranging in 25-50 nM
CSN13428 BI-78D3   883065-90-5 BI-78D3 is a selective and competitive JNK inhibitor with IC50 of 280 nM
CSN10356 Auraptene   495-02-3 Auraptene is a natural product isolated and purified from the peel of Poncirus trifoliata with anti-tumor and anti-oxidant activity. Auraptene-mediated activation of JNK may contribute to the production of Aβ by promoting γ-secretase activity.
CSN18465 AS-602801 848344-36-5 AS-602801 is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.
CSN18229 AS-601245 345987-15-7 AS-601245 is an inhibitor of the c-Jun NH2-terminal kinase JNK hJNK1 IC50150nM hJNK2 IC50220nM and hJNK3 IC5070 nM has neuroprotective properties
CSN10317 Anisomycin   22862-76-6 Anisomycin is a naturally occuring antibiotic which can act as a potent activator of stress-activated protein kinases (JNKSAPK) and p38 MAPK, and also can inhibit protein synthesis by blocking translation.
CSN22669 AEG 3482 63735-71-7 AEG 3482 is an inhibitor of c-jun N-terminal kinase (JNK) signaling.
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