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JAK

JAK

Cat. No. Product Name CAS No. Information
CSN12405 TG 101348   936091-26-8 TG 101348 is an inhibitor of JAK2 with an IC of 6 nM and also inhibits related kinases FLT3, RET, and JAK3 with less potent activity, having IC values of 25, 17 and 169 nM, respectively.
CSN23211 ZM 449829 4452-06-6 Potent, selective JAK3 inhibitor
CSN23010 NSC 33994 82058-16-0 NSC 33994 is a selective inhibitor of JAK2 with IC50 of 60 nM.
CSN23158 TCS 21311 1260181-14-3 NIBR3049, also known as TCS-21311, is a potent and selective JAK3 inhibitor IC50 values of 8 nM..
CSN11462 Mollugin 55481-88-4 Mollugin, a natural product isolated and purified from the roots of Rubia cordifolia L., may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway.
CSN14154 Dehydrocrenatidine 65236-62-6 Dehydrocrenatidine, a natural product isolated and purified from the barks of Picrasma quassioides, is a JAK-specific inhibitor, which inhibits JAK2-JH1 kinase activity in vitro , represses constitutively activated JAK2 and STAT3, as well as interleukin-6-, interferon--, and interferon--stimulated JAK activity, and STAT phosphorylation, and suppresses STAT3 and STAT1 downstream gene expression.
CSN22692 Atiprimod 2HCl 130065-61-1 Atiprimod 2HCl is an inhibitor JAK2 with IC50 of 397 nM.
CSN19970 Curculigoside 85643-19-2
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