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JAK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN12405 | TG 101348 | 936091-26-8 | TG 101348 is an inhibitor of JAK2 with an IC of 6 nM and also inhibits related kinases FLT3, RET, and JAK3 with less potent activity, having IC values of 25, 17 and 169 nM, respectively. |
| CSN23211 | ZM 449829 | 4452-06-6 | Potent, selective JAK3 inhibitor |
| CSN23010 | NSC 33994 | 82058-16-0 | NSC 33994 is a selective inhibitor of JAK2 with IC50 of 60 nM. |
| CSN11462 | Mollugin | 55481-88-4 | Mollugin, a natural product isolated and purified from the roots of Rubia cordifolia L., may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. |
| CSN14154 | Dehydrocrenatidine | 65236-62-6 | Dehydrocrenatidine, a natural product isolated and purified from the barks of Picrasma quassioides, is a JAK-specific inhibitor, which inhibits JAK2-JH1 kinase activity in vitro , represses constitutively activated JAK2 and STAT3, as well as interleukin-6-, interferon--, and interferon--stimulated JAK activity, and STAT phosphorylation, and suppresses STAT3 and STAT1 downstream gene expression. |
| CSN19970 | Curculigoside | 85643-19-2 |
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