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IRE1

IRE1

Cat. No. Product Name CAS No. Information
CSN18196 STF-083010   307543-71-1 STF-083010 is a potent IRE1 endonuclease inhibitor which can block endogenous XBP1 mRNA splicing
CSN23751 MKC8866 1338934-59-0 MKC8866 is an inositol requiring enzyme 1 IRE-1 inhibitor with IC5001 M
CSN18840 MKC3946 1093119-54-0 MKC3946 is a small-molecule IRE1 endoribonuclease domain inhibitor which can block XBP1 splicing
CSN21972 KIRA6 1589527-65-0 In INS-1 cells KIRA6 inhibits IRE1 auto-phosphorylation by Tg and XBP1 mRNA splicing by Tm in a dose-dependent manner
CSN17575 APY29 1216665-49-4 APY29 is an allosteric modulator of IRE1 and inhibits IRE1 autophosphorylation IC50 280 nM and activates IRE1 RNase activity
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