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Integrin

Integrin

Cat. No. Product Name CAS No. Information
CSN13160 Zaurategrast 455264-31-0 Zaurategrast is an oral 4-integrin inhibitor.
CSN13433 TR-14035 232271-19-1 TR-14035 is a dual antagonist of both integrin 47 and integrin 41 with IC50 values of 7 nM and 87 nM, respectively, used as an anti-inflammatory agent.
CSN12096 Tirofiban 144494-65-5 Tirofiban is a non-peptide reversible antagonist of the platelet integrin glycoprotein (GP) IIbIIIa receptor used as an antiplatelet drug.
CSN12097 Tirofiban HCl H2O   150915-40-5 Tirofiban HCl H2O is a non-peptide reversible antagonist of the platelet integrin glycoprotein GP IIbIIIa receptor used as an antiplatelet drug
CSN22191 MK-0429 227963-15-7 MK-0429 is a potent integrin antagonist with IC50s of 12.2 nM (51 integrin) and 2.8 nM (v3 integrin), respectively.
CSN21154 Lifitegrast   1025967-78-5 Lifitegrast is a novel small molecule integrin antagonist which can inhibit an integrin, lymphocyte function-associated antigen 1 (LFA-1), from binding to intercellular adhesion molecule 1 (ICAM-1).
CSN19077 Leukadherin-1 344897-95-6 Leukadherin-1 is allosteric activator of CD11bCD18 with EC50 value of 4 M for increasing CD11bCD18-dependent cell adhesion to fibrinogen.
CSN18350 Integrin Antagonist 27 593274-97-6 Integrin antagonist 27 is a small molecule integrin v3 antagonist with binding affinity of 18 nM as an anticancer agent
CSN17970 Integrin Antagonist 1 HCl 1629249-40-6 Integrin antagonist 1 hydrochloride is a small molecule integrin v6 antagonist
CSN20182 GLPG0187 1320346-97-1 GLPG0187 is a small molecule integrin receptor antagonist IRA with potential antineoplastic activity and inhibits v1-integrin with an IC50 of 13 nM
CSN17362 Firategrast 402567-16-2 Firategrast is an orally bioavailable alpha4 beta1alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system CNS
CSN10925 Eptifibatide   188627-80-7 Eptifibatide is a specific inhibitor of fibrinogen working by binding to the platelet membrane integrin IIb3 receptor and preventing platelet aggregation
CSN18950 E-7820 289483-69-8 E7820 is an angiogenesis inhibitor by suppressing integrin a2 a cell adhesion molecule expressed on endothelial cells
CSN19215 Cyclo(RGDyK) 250612-42-1 CycloRGDyK is a highly potent and selective inhibitor for the v3 integrin with a IC50 of 094 nM
CSN19214 Cyclo(-RGDfK) Trifluoroacetate 500577-51-5 Cyclo-RGDfK Trifluoroacetate is a highly potent and selective inhibitor for the v3 integrin with a IC50 of 094 nM
CSN17206 CWHM-12 1564286-55-0 CWHM-12 is a small molecule inhibitor of V integrins with IC50s of 18081502 nM for v1v3v8 and is less potency on v5 IC5061 nM and on inhibition on IIb321101
CSN19182 Cilengitide Trifluoroacetate   199807-35-7 Cilengitide Trifluoroacetate is a cyclic RGD pentapeptide antagonist of integrins v3 v5 and 51
CSN17349 Cilengitide 188968-51-6 Cilengitide is a cyclic RGD pentapeptide antagonist of integrins v3 v5 and 51
CSN18555 ATN-161 Trifluoroacetate 904763-27-5 ATN-161 trifluoroacetate is a five-amino-acid peptide derived from the synergy region of fibronectin and a beta integrin antagonist with antitumor activity.
CSN18167 ATN-161   262438-43-7 ATN-161 is a five-amino-acid peptide derived from the synergy region of fibronectin and a beta integrin antagonist with antitumor activity
CSN10335 Arg-Gly-Asp-Ser   91037-65-9 Arg-Gly-Asp-Ser RGDS is a synthetic integrin antagonist a specific peptide motif through which extracellular matrix ECM components interact with integrin and can modify the behavior of cells
CSN23536 Arg-Gly-Asp TFA   120103-89-1 Arg-Gly-Asp TFA is the TFA salt form of Arg-Gly-Asp which is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins
CSN10333 Arg-Gly-Asp 99896-85-2 Arg-Gly-Asp is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
CSN16418 A-205804 251992-66-2 A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively
CSN13784 SB-273005 205678-31-5
CSN22550 Eptifibatide Acetate 148031-34-9
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