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Integrin
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN13160 | Zaurategrast | 455264-31-0 | Zaurategrast is an oral 4-integrin inhibitor. |
| CSN13433 | TR-14035 | 232271-19-1 | TR-14035 is a dual antagonist of both integrin 47 and integrin 41 with IC50 values of 7 nM and 87 nM, respectively, used as an anti-inflammatory agent. |
| CSN12096 | Tirofiban | 144494-65-5 | Tirofiban is a non-peptide reversible antagonist of the platelet integrin glycoprotein (GP) IIbIIIa receptor used as an antiplatelet drug. |
| CSN12097 | Tirofiban hydrochloride monohydrate | 150915-40-5 | Tirofiban HCl H2O is a non-peptide reversible antagonist of the platelet integrin glycoprotein GP IIbIIIa receptor used as an antiplatelet drug |
| CSN32450 | Zalunfiban | 1448313-27-6 | RUC-4 is an aIIbß3 antagonist for prehospital therapy of myocardial infarction. |
| CSN22191 | MK-0429 | 227963-15-7 | MK-0429 is a potent integrin antagonist with IC50s of 12.2 nM (51 integrin) and 2.8 nM (v3 integrin), respectively. |
| CSN21154 | Lifitegrast | 1025967-78-5 | Lifitegrast is a novel small molecule integrin antagonist which can inhibit an integrin, lymphocyte function-associated antigen 1 (LFA-1), from binding to intercellular adhesion molecule 1 (ICAM-1). |
| CSN19077 | Leukadherin-1 | 344897-95-6 | Leukadherin-1 is allosteric activator of CD11bCD18 with EC50 value of 4 M for increasing CD11bCD18-dependent cell adhesion to fibrinogen. |
| CSN18350 | Integrin Antagonists 27 | 593274-97-6 | Integrin antagonist 27 is a small molecule integrin v3 antagonist with binding affinity of 18 nM as an anticancer agent |
| CSN17970 | (S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((R)-3-(2-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic acid xhydrochloride | 1629249-40-6 | Integrin antagonist 1 HCl is a small molecule integrin αvβ6 antagonist. |
| CSN28434 | GLPG0187 | 1320346-97-1 | GLPG 0187 is a potent αv integrin inhibitor with IC50 values of 1.2-3.7 nM. It inhibits osteoclastic bone resorption and angiogenesis in vitro and in vivo. Also it suppresses epithelial-mesenchymal transition (EMT) and migration of PC-3M-Pro4/luc cells, without inhibiting cell growth. |
| CSN21652 | Fradafiban | 148396-36-5 | Fradafiban is a glycoprotein IIb/IIIa receptor antagonist. |
| CSN17362 | Firategrast | 402567-16-2 | Firategrast is an orally bioavailable alpha4 beta1alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system CNS |
| CSN10925 | Eptifibatide | 188627-80-7 | Eptifibatide is a specific inhibitor of fibrinogen working by binding to the platelet membrane integrin IIb3 receptor and preventing platelet aggregation |
| CSN22550 | Eptifibatide xAcetate | 881997-86-0 | Eptifibatide Acetate is a cyclic heptapeptide that shows the inhibition of platelet glycoprotein IIb/IIIa in acute coronary syndromes. |
| CSN18950 | E7820 | 289483-69-8 | E7820 is an angiogenesis inhibitor by suppressing integrin a2 a cell adhesion molecule expressed on endothelial cells |
| CSN19215 | Cyclo(RGDyK) trifluoroacetate | 250612-42-1 | CycloRGDyK is a highly potent and selective inhibitor for the v3 integrin with a IC50 of 094 nM |
| CSN19214 | Cyclo(-RGDfK) TFA | 500577-51-5 | Cyclo-RGDfK Trifluoroacetate is a highly potent and selective inhibitor for the v3 integrin with a IC50 of 094 nM |
| CSN17951 | Cyclo(-RGDfK) | 161552-03-0 | Cyclo-RGDfK is a potent and selective inhibitor of the v3 integrin |
| CSN18421 | Cyclo(RADfK) | 756500-23-9 | Cyclo(RADfK) is a selective (v)(3) integrin ligand that has been extensively used for research, therapy, and diagnosis of neoangiogenesis. |
| CSN17206 | CWHM-12 | 1564286-55-0 | CWHM-12 is a small molecule inhibitor of V integrins with IC50s of 18081502 nM for v1v3v8 and is less potency on v5 IC5061 nM and on inhibition on IIb321101 |
| CSN19182 | Cilengitide TFA | 199807-35-7 | Cilengitide Trifluoroacetate is a cyclic RGD pentapeptide antagonist of integrins v3 v5 and 51 |
| CSN17349 | Cilengitide | 188968-51-6 | Cilengitide is a cyclic RGD pentapeptide antagonist of integrins v3 v5 and 51 |
| CSN32619 | BMS-688521 | 893397-44-9 | Cell Adhesion Inhibitors, LFA-1/ICAM-1 Interaction Inhibitors |
| CSN18555 | ATN-161 trifluoroacetate salt | 904763-27-5 | ATN-161 trifluoroacetate is a five-amino-acid peptide derived from the synergy region of fibronectin and a beta integrin antagonist with antitumor activity. |
| CSN18167 | ATN-161 | 262438-43-7 | ATN-161 is a five-amino-acid peptide derived from the synergy region of fibronectin and a beta integrin antagonist with antitumor activity |
| CSN10335 | Arg-Gly-Asp-Ser | 91037-65-9 | Arg-Gly-Asp-Ser RGDS is a synthetic integrin antagonist a specific peptide motif through which extracellular matrix ECM components interact with integrin and can modify the behavior of cells |
| CSN10333 | RGD | 99896-85-2 | Arg-Gly-Asp is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins. |
| CSN24771 | ADH-503 | 2055362-74-6 | ADH-503 is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression. |
| CSN16418 | A-205804 | 251992-66-2 | A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 expression with IC50 of 20 nM and 25 nM respectively |
| CSN67365 | BMS-587101 | 509083-77-6 | |
| CSN83369 | Tirofiban hydrochloride | 142373-60-2 |
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