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IL Receptor
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN10040 | YM-90709 | 163769-88-8 | YM-90709 is a competitive and selective IL-5 receptor antagonist with IC50 value ranging in 0.45 - 1 mM. |
| CSN12018 | Suplatast Tosylate | 94055-76-2 | Suplatast Tosylate is an inhibitor of Th2 cytokine synthesis which can attenuate IL-2, IL-5 and IL-13 production and has no effect on IFN- production. |
| CSN22032 | IX 207-887 | 98320-39-9 | IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1). |
| CSN22936 | IL-1R Antagonist | 566914-00-9 | IL-1R antagonist is a peptide mimic of the myeloid differentiation primary response gene 88 (MyD88) that changes the interaction of MyD88 and IL-1 receptor type I. |
| CSN22931 | GIBH-130 | 1252608-59-5 | GIBH-130 can suppress IL-1 secretion via activating microglia with IC50 of 34 nM and has effect on neuroinflammation |
| CSN21215 | Esonarimod | 101973-77-7 | Esonarimod is an antirheumatic drug and IL-1 inhibitor. |
| CSN10460 | Disulfiram | 97-77-8 | Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram acts as an allosteric inhibitor of MERS-CoV PLpro but as a competitive (or mixed) inhibitor of SARS-CoV PLpro. |
| CSN16710 | Diacerein | 13739-02-1 | Diacerein is a symptomatic slow-acting medicine in osteoarthritis which can reduce the level of IL-1 receptors leading to fewer receptors to form heterodimer complexes. |
| CSN22771 | CP 424174 | 210825-31-3 | CP 424174 is an inhibitor of IL-1β post-translational processing with IC50 of 210 nM. |
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