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IKK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN15918 | WS3 | 1421227-52-2 | WS3 is an Erb3 binding protein-1 (EBP1) and IB kinase pathway modulator, its a non-specific proliferative molecule and promotes cell proliferation with EC50 of 28 nM. |
| CSN13432 | TPCA-1 | 507475-17-4 | TPCA-1 is a selective and potent IKK- inhibitor with IC50 value of 17.9 nM. |
| CSN16524 | SC514 | 354812-17-2 | SC514 is a potent, reversible, ATP-competitive and highly selective IKK-(IKK-2) inhibitor with IC50 value ranging in 3-12 M. |
| CSN18270 | PS-1145 | 431898-65-6 | PS-1145 is an IkappaB kinase (IKK) inhibitor with IC50 of 88 nM. |
| CSN23053 | PS 1145 2HCl | 1049743-58-9 | PS 1145 2HCl is a selective IκB kinase (IKK) inhibitor with IC50 of 100 nM. |
| CSN12718 | PHA-408 | 503555-55-3 | PHA-408 is a potent, highly selective and ATP-competitive IKB kinase-2 (IKK-2) inhibitor (IC50 40 nM). |
| CSN23035 | PF-184 | 1187460-81-6 | PF-184 is a potent and selective IKKβ inhibitor with IC50 of 37 nM. |
| CSN17538 | MRT67307 | 1190378-57-4 | MRT67307 is a dual inhibitor of the IKKe and TBK-1. |
| CSN21103 | MRT67307 2HCl | 1781882-89-0 | MRT67307 HCl is a potent and dual IKKε and TBK1 inhibitor. |
| CSN19224 | MRT67307 HCl | 2095432-39-4 | MRT67307 HCl is a potent and dual IKKε and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively. |
| CSN13105 | MLN120B | 783348-36-7 | MLN120B is a potent and effective IKKbeta inhibitor. |
| CSN18625 | LY2409881 | 946518-61-2 | LY2409881 is a selective inhibitor of IKK2 with IC50 of 30 nM and IC50 for IKK1 and other common kinases is at least one log higher. |
| CSN16201 | LY2409881 3HCl | 946518-60-1 | LY2409881 3HCl is a selective inhibitor of IKK2 with IC50 of 30 nM and IC50 for IKK1 and other common kinases is at least one log higher. |
| CSN16069 | IMD-0354 | 978-62-1 | IMD-0354 is a synthetic selective NF-kB inhibitor and blocks IB phosphorylation in NF-B pathway. |
| CSN16345 | IKKε-IN-1 | 1292310-49-6 | IKK-IN-1 is a potent IKK inhibitor. It inhibits the in-situ K -mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM. |
| CSN18487 | IKK-3 Inhibitor | 862812-98-4 | IKK-3 inhibitor is a potent and selective inhibitor of IKK-epsilon kinase with IC50 of 40 nM and is inactive at IKK- and IKK-. |
| CSN16585 | IKK 16 | 873225-46-8 | IKK 16 is a selective IB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively. |
| CSN22855 | IKK 16 HCl | 1186195-62-9 | IKK 16 HCl is a selective inhibitor of IκB kinase (IKK) with IC50s of 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively. |
| CSN24084 | GSK8612 | 2361659-62-1 | GSK8612 is a potent and highly selective Tank-binding Kinase-1 (TBK1) inhibitor with pIC50 of 6.8 for recombinant TBK1. |
| CSN16421 | BMS-345541 HCl | 547757-23-3 | BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 M and 4 M, respectively. |
| CSN18641 | BI-605906 | 960293-88-3 | BI-605906, an inhibitor of IKK, inhibits IKK with an IC50 value of 380 nM when assayed at 0.1 mM ATP. |
| CSN16657 | BAY 65-1942 R Form | 758683-21-5 | Bay 65-1942 is an ATP-competitive inhibitor that selectively targets IKK kinase. |
| CSN18352 | BAY 65-1942 | 600734-02-9 | Bay 65-1942 is an ATP-competitive inhibitor that selectively targets IKK kinase. |
| CSN16628 | Bay 65-1942 HCl | 600734-06-3 | Bay 65-1942 HCl is an ATP-competitive inhibitor that selectively targets IKKβ kinase. |
| CSN13625 | BAY 11-7085 | 196309-76-9 | BAY 11-7085 is an irreversible inhibitor of TNF-induced IB phosphorylation with IC50 of 10 M. |
| CSN13487 | BAY 11-7082 | 19542-67-7 | BAY 11-7082 is a NF-B inhibitor, inhibits TNF-induced IB phosphorylation with IC50 of 10 M in tumor cells. It also inhibits components of the ubiquitin system through inactivating the E2-conjugating enzymes Ubc (ubiquitin conjugating) 13 and UbcH7 and the E3 ligase LUBAC (linear ubiquitin assembly complex). |
| CSN12828 | Bardoxolone Methyl | 218600-53-4 | Bardoxolone methyl is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities. It is also a potent Nrf2 activator and nuclear factor-B (NF-B) inhibitor. |
| CSN12997 | Bardoxolone | 218600-44-3 | Bardoxolone is a nuclear regulator factor (Nrf-2) activator. |
| CSN17947 | AZD3264 | 1609281-86-8 | AZD3264 is an IkB-kinase IKK2 Inhibitor. IKK2 has been identified as one of the pathways to treat inflammatory conditions such as asthma, chronic pulmonary obstructive disorder (COPD) and rheumatoid arthritis. |
| CSN12359 | Amlexanox | 68302-57-8 | Amlexanox is a selective inhibitor of TBK1 and IKK with IC50 values of 1-2 M. |
| CSN13573 | ACHP HCl | 406209-26-5 | ACHP HCl is a potent and selective IKK-2 inhibitor with IC50 of 8.5 nM. |
| CSN16667 | BMS-345541 | 445430-58-0 |
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