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IKK

IKK

Cat. No. Product Name CAS No. Information
CSN15918 WS3 1421227-52-2 WS3 is an Erb3 binding protein-1 (EBP1) and IB kinase pathway modulator, its a non-specific proliferative molecule and promotes cell proliferation with EC50 of 28 nM.
CSN13432 TPCA-1 507475-17-4 TPCA-1 is a selective and potent IKK- inhibitor with IC50 value of 17.9 nM.
CSN16524 SC514   354812-17-2 SC514 is a potent, reversible, ATP-competitive and highly selective IKK-(IKK-2) inhibitor with IC50 value ranging in 3-12 M.
CSN25345 QUN97653 1893397-65-3 QUN97653 is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively.
CSN16069 IMD-0354 978-62-1 IMD-0354 is a synthetic selective NF-kB inhibitor and blocks IB phosphorylation in NF-B pathway.
CSN16345 IKKε-IN-1 1292310-49-6 IKK-IN-1 is a potent IKK inhibitor. It inhibits the in-situ K -mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM.
CSN22855 IKK 16 HCl 1186195-62-9 IKK 16 HCl is a selective inhibitor of IκB kinase (IKK) with IC50s of 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively.
CSN27231 GS143   916232-21-8 GS143 is a selective IκBα ubiquitination inhibitor with an IC50 of 5.2 μM for SCFβTrCP1-mediated IκBα ubiquitylation. GS143 sup­presses NF-κB activation and transcription of target genes and does not inhibit proteasome activity. GS143 has anti-asthma effect .
CSN12711 BX795   702675-74-9 BX795 is a potent and selective dual inhibitor of TBK1PDK1 with IC50s of 2 nM6 nM respectively also inhibit Aurora B and IB kinase IKK
CSN16657 BAY 65-1942 R Form 758683-21-5 Bay 65-1942 is an ATP-competitive inhibitor that selectively targets IKK kinase.
CSN18352 BAY 65-1942 600734-02-9 Bay 65-1942 is an ATP-competitive inhibitor that selectively targets IKK kinase.
CSN13625 BAY 11-7085 196309-76-9 BAY 11-7085 is an irreversible inhibitor of TNF-induced IB phosphorylation with IC50 of 10 M.
CSN13487 BAY 11-7082   19542-67-7 BAY 11-7082 is a NF-B inhibitor, inhibits TNF-induced IB phosphorylation with IC50 of 10 M in tumor cells. It also inhibits components of the ubiquitin system through inactivating the E2-conjugating enzymes Ubc (ubiquitin conjugating) 13 and UbcH7 and the E3 ligase LUBAC (linear ubiquitin assembly complex).
CSN12997 Bardoxolone 218600-44-3 Bardoxolone is a nuclear regulator factor (Nrf-2) activator.
CSN17947 AZD3264 1609281-86-8 AZD3264 is an IkB-kinase IKK2 Inhibitor. IKK2 has been identified as one of the pathways to treat inflammatory conditions such as asthma, chronic pulmonary obstructive disorder (COPD) and rheumatoid arthritis.
CSN12359 Amlexanox   68302-57-8 Amlexanox is a selective inhibitor of TBK1 and IKK with IC50 values of 1-2 M.
CSN13573 ACHP HCl 406209-26-5 ACHP HCl is a potent and selective IKK-2 inhibitor with IC50 of 8.5 nM.
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