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IKK

IKK

Cat. No. Product Name CAS No. Information
CSN15918 WS3 1421227-52-2 WS3 is an Erb3 binding protein-1 (EBP1) and IB kinase pathway modulator, its a non-specific proliferative molecule and promotes cell proliferation with EC50 of 28 nM.
CSN16524 SC514   354812-17-2 SC514 is a potent, reversible, ATP-competitive and highly selective IKK-(IKK-2) inhibitor with IC50 value ranging in 3-12 M.
CSN16069 IMD-0354 978-62-1 IMD-0354 is a synthetic selective NF-kB inhibitor and blocks IB phosphorylation in NF-B pathway.
CSN22855 IKK 16 HCl 1186195-62-9 IKK 16 HCl is a selective inhibitor of IκB kinase (IKK) with IC50s of 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively.
CSN13625 BAY 11-7085 196309-76-9 BAY 11-7085 is an irreversible inhibitor of TNF-induced IB phosphorylation with IC50 of 10 M.
CSN13487 BAY 11-7082   19542-67-7 BAY 11-7082 is a NF-B inhibitor, inhibits TNF-induced IB phosphorylation with IC50 of 10 M in tumor cells. It also inhibits components of the ubiquitin system through inactivating the E2-conjugating enzymes Ubc (ubiquitin conjugating) 13 and UbcH7 and the E3 ligase LUBAC (linear ubiquitin assembly complex).
CSN17947 AZD3264 1609281-86-8 AZD3264 is an IkB-kinase IKK2 Inhibitor. IKK2 has been identified as one of the pathways to treat inflammatory conditions such as asthma, chronic pulmonary obstructive disorder (COPD) and rheumatoid arthritis.
CSN12359 Amlexanox   68302-57-8 Amlexanox is a selective inhibitor of TBK1 and IKK with IC50 values of 1-2 M.
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