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IKK

IKK

Cat. No. Product Name CAS No. Information
CSN15918 WS3 1421227-52-2 WS3 is an Erb3 binding protein-1 (EBP1) and IB kinase pathway modulator, its a non-specific proliferative molecule and promotes cell proliferation with EC50 of 28 nM.
CSN13432 TPCA-1 507475-17-4 TPCA-1 is a selective and potent IKK- inhibitor with IC50 value of 17.9 nM.
CSN16524 SC514   354812-17-2 SC514 is a potent, reversible, ATP-competitive and highly selective IKK-(IKK-2) inhibitor with IC50 value ranging in 3-12 M.
CSN18270 PS-1145 431898-65-6 PS-1145 is an IkappaB kinase (IKK) inhibitor with IC50 of 88 nM.
CSN12718 PHA-408 503555-55-3 PHA-408 is a potent, highly selective and ATP-competitive IKB kinase-2 (IKK-2) inhibitor (IC50 40 nM).
CSN17538 MRT67307 1190378-57-4 MRT67307 is a dual inhibitor of the IKKe and TBK-1.
CSN21103 MRT67307 2HCl 1781882-89-0 MRT67307 Hydrochloride is a potent and dual IKK and TBK1 inhibitor.
CSN19224 MRT67307 HCl 2095432-39-4 MRT67307 Hydrochloride is a potent and dual IKK and TBK1 inhibitor with IC50 of 160 and 19 nM, respectively.
CSN13105 MLN120B 783348-36-7 MLN120B is a potent and effective IKKbeta inhibitor.
CSN16201 LY2409881 3HCl   946518-60-1 LY2409881 trihydrochloride is a selective inhibitor of IKK2 with IC50 of 30 nM and IC50 for IKK1 and other common kinases is at least one log higher.
CSN18625 LY2409881 946518-61-2 LY2409881 is a selective inhibitor of IKK2 with IC50 of 30 nM and IC50 for IKK1 and other common kinases is at least one log higher.
CSN16069 IMD-0354 978-62-1 IMD-0354 is a synthetic selective NF-kB inhibitor and blocks IB phosphorylation in NF-B pathway.
CSN16345 IKKε-IN-1 1292310-49-6 IKK-IN-1 is a potent IKK inhibitor. It inhibits the in-situ K -mediated phosphorylation of IRF3 with an IC50 value of less than about 100 nM.
CSN18487 IKK-3 Inhibitor 862812-98-4 IKK-3 inhibitor is a potent and selective inhibitor of IKK-epsilon kinase with IC50 of 40 nM and is inactive at IKK- and IKK-.
CSN16585 IKK 16 873225-46-8 IKK 16 is a selective IB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
CSN16421 BMS-345541 HCl 547757-23-3 BMS-345541 is a highly selective inhibitor of the catalytic subunits of IKK-2 and IKK-1 with IC50 of 0.3 M and 4 M, respectively.
CSN18641 BI-605906 960293-88-3 BI-605906, an inhibitor of IKK, inhibits IKK with an IC50 value of 380 nM when assayed at 0.1 mM ATP.
CSN16657 BAY 65-1942 R Form 758683-21-5 Bay 65-1942 is an ATP-competitive inhibitor that selectively targets IKK kinase.
CSN18352 BAY 65-1942 600734-02-9 Bay 65-1942 is an ATP-competitive inhibitor that selectively targets IKK kinase.
CSN16628 Bay 65-1942 HCl 600734-06-3 Bay 65-1942 hydrochloride is an ATP-competitive inhibitor that selectively targets IKK kinase.
CSN13625 BAY 11-7085 196309-76-9 BAY 11-7085 is an irreversible inhibitor of TNF-induced IB phosphorylation with IC50 of 10 M.
CSN13487 BAY 11-7082   19542-67-7 BAY 11-7082 is a NF-B inhibitor, inhibits TNF-induced IB phosphorylation with IC50 of 10 M in tumor cells. It also inhibits components of the ubiquitin system through inactivating the E2-conjugating enzymes Ubc (ubiquitin conjugating) 13 and UbcH7 and the E3 ligase LUBAC (linear ubiquitin assembly complex).
CSN12828 Bardoxolone Methyl   218600-53-4 Bardoxolone methyl is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities. It is also a potent Nrf2 activator and nuclear factor-B (NF-B) inhibitor.
CSN12997 Bardoxolone 218600-44-3 Bardoxolone is a nuclear regulator factor (Nrf-2) activator.
CSN17947 AZD3264 1609281-86-8 AZD3264 is an IkB-kinase IKK2 Inhibitor. IKK2 has been identified as one of the pathways to treat inflammatory conditions such as asthma, chronic pulmonary obstructive disorder (COPD) and rheumatoid arthritis.
CSN12359 Amlexanox   68302-57-8 Amlexanox is a selective inhibitor of TBK1 and IKK with IC50 values of 1-2 M.
CSN13573 ACHP HCl 406209-26-5 ACHP hydrochloride is a potent and selective IKK-2 inhibitor with IC50 of 8.5 nM.
CSN16667 BMS-345541 445430-58-0
CSN23035 PF-184 1187460-81-6
CSN23053 PS 1145 2HCl 1049743-58-9
CSN23051 PR 39 (Porcine) 139637-11-9
CSN22855 IKK 16 1186195-62-9
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