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IKK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN15918 | WS3 | 1421227-52-2 | WS3 is an Erb3 binding protein-1 (EBP1) and IB kinase pathway modulator, its a non-specific proliferative molecule and promotes cell proliferation with EC50 of 28 nM. |
| CSN16524 | SC514 | 354812-17-2 | SC514 is a potent, reversible, ATP-competitive and highly selective IKK-(IKK-2) inhibitor with IC50 value ranging in 3-12 M. |
| CSN16069 | IMD-0354 | 978-62-1 | IMD-0354 is a synthetic selective NF-kB inhibitor and blocks IB phosphorylation in NF-B pathway. |
| CSN22855 | IKK 16 HCl | 1186195-62-9 | IKK 16 HCl is a selective inhibitor of IκB kinase (IKK) with IC50s of 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively. |
| CSN13625 | BAY 11-7085 | 196309-76-9 | BAY 11-7085 is an irreversible inhibitor of TNF-induced IB phosphorylation with IC50 of 10 M. |
| CSN13487 | BAY 11-7082 | 19542-67-7 | BAY 11-7082 is a NF-B inhibitor, inhibits TNF-induced IB phosphorylation with IC50 of 10 M in tumor cells. It also inhibits components of the ubiquitin system through inactivating the E2-conjugating enzymes Ubc (ubiquitin conjugating) 13 and UbcH7 and the E3 ligase LUBAC (linear ubiquitin assembly complex). |
| CSN17947 | AZD3264 | 1609281-86-8 | AZD3264 is an IkB-kinase IKK2 Inhibitor. IKK2 has been identified as one of the pathways to treat inflammatory conditions such as asthma, chronic pulmonary obstructive disorder (COPD) and rheumatoid arthritis. |
| CSN12359 | Amlexanox | 68302-57-8 | Amlexanox is a selective inhibitor of TBK1 and IKK with IC50 values of 1-2 M. |
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