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IDO
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN16276 | PF-06840003 | 198474-05-4 | PF-06840003 is a highly selective orally bioavailable IDO-1 inhibitor with IC50 of 041 M |
| CSN13930 | NLG919 | 1402836-58-1 | NLG919 is a potent IDO indoleamine-23-dioxygenase pathway inhibitor with KiEC50 of 7 nM75 nM in cell-free assays |
| CSN15702 | Indoximod | 110117-83-4 | Indoximod is an indoleamine 2,3-dioxygenase (IDO) pathway inhibitor with a Ki of 19 M. |
| CSN15728 | INCB024360 Analogue | 914471-09-3 | INCB024360 analogue is a potent competitive IDO1 indoleamine-23-dioxygenase inhibitor with IC50 of 67 nM |
| CSN17798 | IDO-IN-8 | 1402837-77-7 | IDO-IN-8 is a potent human IDO inhibitor with IC50 of 1-10 M |
| CSN17799 | Navoximod | 1402837-78-8 | IDO-IN-7 is a potent human IDO inhibitor with IC50 of 1 M |
| CSN17797 | IDO-IN-6 | 1402837-76-6 | IDO-IN-6 is a potent human IDO inhibitor with IC50 of 1 M |
| CSN17800 | IDO-IN-5 | 1402837-79-9 | IDO-IN-5 is a potent human IDO inhibitor with IC50 of 1-10 M |
| CSN17969 | IDO-IN-4 | 1629125-65-0 | IDO-IN-4 is a potent IDO1 inhibitor with IC50 of 8 nM in human IDO1HEK293 cells |
| CSN19054 | IDO-IN-3 | 2070018-30-1 | IDO-IN-3 is a potent IDO inhibitor |
| CSN19043 | IDO-IN-2 | 1668565-74-9 | IDO-IN-2 is an IDO inhibitor with IC50 value of 68 nM and 160 nM in HeLa cell and HEK293 cell respectively |
| CSN16919 | IDO-IN-1 | 914638-30-5 | IDO-IN-1 is an indoleamine-23-dioxygenase IDO inhibitor with IC50 of 59 nM shows activity in Hela cell IC5012 nM |
| CSN13892 | Epacadostat | 1204669-58-8 | Epacadostat is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). |
| CSN10692 | Coptisine | 3486-66-6 | Coptisine is a protoberberine isoquinoline alkaloid isolated and purified from the herbs of Chelidonium majus L., which can increases cell viability based on its reversal effect on the enhanced activity of Indoleamine 2,3-dioxygenase . |
| CSN18353 | Coptisine Chloride | 6020-18-4 | Coptisine Chloride is a naturally occuring cytotoxic alkaloid found in Chinese goldthread which shows cytotoxic effect on heptoma and leukemic cells and is reported to block cell cycle progression. |
| CSN20317 | BMS-986205 | 1923833-60-6 | BMS-986205 is a specific and irreversible inhibitor of IDO1 with IC50 value of 17 nM |
| CSN19041 | 8-Nitrotryptanthrin | 77603-42-0 | 8-Nitrotryptanthrin is a potent human indoleamine 23-dioxygenase 2 hIDO2 inhibitor which significantly reduces IDO2 activity with Ki of 097 M |
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