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IDH

IDH

Cat. No. Product Name CAS No. Information
CSN22566 Vorasidenib 1644545-52-7 Vorasidenib is an isocitrate dehydrogenase IDH inhibitor
CSN19057 (R,S)-Ivosidenib 2070009-31-1 RS-Ivosidenib is an inhibitor of isocitrate dehydrogenase IDH1
CSN17325 Mutant IDH1-IN-2 1429176-69-1 Mutant IDH1-IN-2 is an inhibitor of mutant isocitrate dehydrogenase IDH proteins with IC50 of in LS-MS biochemical assay IC50 of 166 nM in fluorescence biochemical assay
CSN17324 Mutant IDH1-IN-1 1355326-21-4 Mutant IDH1-IN-1 is a potent mutant IDH1 R132H inhibitor with IC50 < 0.1 μM.
CSN17836 Mutant IDH1 inhibitor 1429180-08-4 Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of 72 nM
CSN23687 IDH-305 1628805-46-8 IDH-305 is a selective inhibitor of IDH1 R132H and R132C with IC50 of 18 and 28 nM respectively
CSN21984 GSK864 1816331-66-4 GSK864 is an isocitrate dehydrogenase 1 (IDH1) mutant inhibitor which inhibits IDH1 mutants R132C, R132H, and R132G with IC50 values of 8.8, 15.2 and 16.6 nM.
CSN21994 Enasidenib mesylate 1650550-25-6 Enasidenib mesylate is a first-in-class, oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes.
CSN17069 Enasidenib 1446502-11-9 Enasidenib is a selective mutant IDH2 enzyme inhibitor with IC50 of 12 nM
CSN25248 DS-1001b 1898207-64-1 DS-1001b is a novel selective mutant IDH1 inhibitor with antitumor activity.
CSN10737 D-α-Hydroxyglutaric acid disodium   103404-90-6 D-alpha-Hydroxyglutaric Acid Disodium is a multiple-target inhibitor of KDM4A and -Ketoglutarate(-KG)-dependent dioxygenase, as well as an NF-B activator.
CSN19688 BAY-1436032 1803274-65-8 BAY 1436032 is a potent selective and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 mIDH1
CSN13819 AGI-6780 1432660-47-3 AGI-6780 is a selective inhibitor of IDH2R140Q mutant with IC50 value of 23 nM
CSN16218 AGI-5198 1355326-35-0 AGI-5198 is a potent and selective inhibitor of IDH1 R132H and R132C mutants with IC50 values of 007 and 016 M respectively but not wild-type IDH1 wild-type IDH2 or IDH2 mutants
CSN19720 AG-120 (racemic) 1448346-63-1 AG-120 Racemate is the racemate form of AG-120 with no activity
CSN17323 Ivosidenib   1448347-49-6 AG-120 is a first-in-class mutant IDH1 inhibitor
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