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IDH
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN22566 | Vorasidenib | 1644545-52-7 | Vorasidenib is an isocitrate dehydrogenase IDH inhibitor |
| CSN19057 | (R,S)-Ivosidenib | 2070009-31-1 | RS-Ivosidenib is an inhibitor of isocitrate dehydrogenase IDH1 |
| CSN17325 | Mutant IDH1-IN-2 | 1429176-69-1 | Mutant IDH1-IN-2 is an inhibitor of mutant isocitrate dehydrogenase IDH proteins with IC50 of in LS-MS biochemical assay IC50 of 166 nM in fluorescence biochemical assay |
| CSN17324 | Mutant IDH1-IN-1 | 1355326-21-4 | Mutant IDH1-IN-1 is a potent mutant IDH1 R132H inhibitor with IC50 < 0.1 μM. |
| CSN17836 | Mutant IDH1 inhibitor | 1429180-08-4 | Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of 72 nM |
| CSN23687 | IDH-305 | 1628805-46-8 | IDH-305 is a selective inhibitor of IDH1 R132H and R132C with IC50 of 18 and 28 nM respectively |
| CSN21984 | GSK864 | 1816331-66-4 | GSK864 is an isocitrate dehydrogenase 1 (IDH1) mutant inhibitor which inhibits IDH1 mutants R132C, R132H, and R132G with IC50 values of 8.8, 15.2 and 16.6 nM. |
| CSN21994 | Enasidenib mesylate | 1650550-25-6 | Enasidenib mesylate is a first-in-class, oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes. |
| CSN17069 | Enasidenib | 1446502-11-9 | Enasidenib is a selective mutant IDH2 enzyme inhibitor with IC50 of 12 nM |
| CSN25248 | DS-1001b | 1898207-64-1 | DS-1001b is a novel selective mutant IDH1 inhibitor with antitumor activity. |
| CSN10737 | D-α-Hydroxyglutaric acid disodium | 103404-90-6 | D-alpha-Hydroxyglutaric Acid Disodium is a multiple-target inhibitor of KDM4A and -Ketoglutarate(-KG)-dependent dioxygenase, as well as an NF-B activator. |
| CSN19688 | BAY-1436032 | 1803274-65-8 | BAY 1436032 is a potent selective and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 mIDH1 |
| CSN13819 | AGI-6780 | 1432660-47-3 | AGI-6780 is a selective inhibitor of IDH2R140Q mutant with IC50 value of 23 nM |
| CSN16218 | AGI-5198 | 1355326-35-0 | AGI-5198 is a potent and selective inhibitor of IDH1 R132H and R132C mutants with IC50 values of 007 and 016 M respectively but not wild-type IDH1 wild-type IDH2 or IDH2 mutants |
| CSN19720 | AG-120 (racemic) | 1448346-63-1 | AG-120 Racemate is the racemate form of AG-120 with no activity |
| CSN17323 | Ivosidenib | 1448347-49-6 | AG-120 is a first-in-class mutant IDH1 inhibitor |
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