Welcome to CSNpharm! For Research Use Only!
Home +1-708-781-1677 sales@csnpharm.com    

HSP

HSP

Cat. No. Product Name CAS No. Information
CSN16304 XL888 1149705-71-4 XL888 is a specific and ATP-competitive Hsp90 inhibitor with IC50 of 24 nM
CSN13596 VER-50589 747413-08-7 VER-50589 is an isoxazole compound that inhibits Hsp90 with an IC50 value of 21 nM
CSN18335 VER-49009 558640-51-0 VER-49009 is a pyrazole compound that inhibits Hsp90 with an IC50 value of 47 nM
CSN13116 VER-155008 1134156-31-2 VER-155008 is a potent Hsp70 family inhibitor with IC50 of 05 M 26 M and 26 M in cell-free assays for HSP70 HSC70 and GRP78 respectively 100-fold selectivity over HSP90
CSN20345 TRC051384 867164-40-7 TRC051384 is a inducer of Hsp70
CSN20344 TRC051384 HCl   1333327-56-2 TRC051384 HCl is a potent inducer of HSP70 which can induce HSP70B mRNA expression.
CSN12051 Teprenone   6809-52-5 Teprenone is used as an anti-ulcer drug, a cardioprotective agent, a hepatoprotective agent, a nephroprotective agent, a neuroprotective agent and a Hsp70 inducer.
CSN22232 TAS-116 1260533-36-5 TAS-116 is a potent and selective HSP90 inhibitor with Kis of 347 nM 213 nM respectively
CSN16517 SNX-2112 908112-43-6 SNX-2112 is a potent synthetic heat shock protein 90 HSP90 inhibitor with an IC50 of 092 M for K562 cells
CSN18481 Retaspimycin 857402-23-4 Retaspimycin is a small-molecule inhibitor of heat shock protein 90 HSP90 with antiproliferative and antineoplastic activities
CSN18482 Retaspimycin HCl 857402-63-2 Retaspimycin HCl is the HCl salt of a small-molecule inhibitor of heat shock protein 90 (HSP90) with antiproliferative and antineoplastic activities.
CSN15760 PU-WS13 1454619-14-7 PU-WS13 is a potent Grp94-specific Hsp90 inhibitor of the purine scaffold class
CSN16046 PU-H 71 873436-91-0 PU-H71 is a potent Hsp90 inhibitor with IC50 of 50 nM
CSN18943 PU-H 71 HCl 2095432-24-7 PU-H71 HCl is a potent Hsp90 inhibitor with IC50 of 50 nM.
CSN11740 Platycodin D 58479-68-8 Platycodin D is a natural product isolated and purified from the root of Platycodon grandiflorum., which may stimulate TNF- synthesis or inhibit degradation of TNF- mRNA, and is an Hsp90 inhibitor which disrupting the co-chaperone interaction of Hsp90cell division cycle protein 37 (Cdc37) and subsequently degrading multiple Hsp90 client proteins without the feedback increase of Hsp70.
CSN17514 PF-04929113 Mesylate 1173111-67-5 PF-04929113 mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM
CSN16541 PF-04929113 908115-27-5 PF-04929113 is a potent and selective HSP90 inhibitor with Kd of 41 nM and induces Her-2 degradation with IC50 of 37 nM
CSN15852 HSP990 934343-74-5 NVP-HSP990 is a potent and selective HSP90 inhibitor for HSP90 with IC50 of 06 nM08 nM
CSN17190 NVP-BEP800 847559-80-2 NVP-BEP800 is a fully synthetic HSP90 inhibitor with IC50 of 58 nM exhibits 70-fold selectivity against Hsp90 family members Grp94 and Trap-1
CSN16765 NMS-E973 1253584-84-7 NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of 10 nM for Hsp90 binding no activiy against a panel of 52 diverse protein kinases
CSN17387 ML346 100872-83-1 ML346 is an activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay
CSN21425 MKT-077   147366-41-4 MKT-077 FJ-776 is a water-soluble rhodacyanine dye with antitumor activity It can bind to Hsp70 family member mortalin-2 and inhibit its interactions with p53
CSN22959 Macbecin I 73341-72-7 Macbecin I is a Hsp90 inhibitor with IC50 of 2 μM.
CSN16562 KW-2478 819812-04-9 KW-2478 is a nonansamycin HSP90 inhibitor with IC50 of 38 nM
CSN18942 KRIBB11 342639-96-7 KRIBB11 is an inhibitor of heat shock factor HSF inhibitor with IC50 of 12 M
CSN15324 Kongensin A 885315-96-8 Kongensin A, a natural product isolated and purified from the herbs of Croton cascarilloides, is an effective heat shock protein 90 (HSP90) inhibitor that has potential anti-necroptosis and anti-inflammation applications.
CSN17321 KNK437   218924-25-5 KNK437 is a pan-HSP inhibitor which inhibits the synthesis of inducible HSPs including HSP105 HSP72 and HSP40
CSN22600 JG98 1456551-16-8 JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor which shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages.
CSN22089 HSP70-IN-1 1268273-90-0 HSP70-IN-1 is a heat shock protein (HSP) inhibitor.
CSN19076 HA15   1609402-14-3 HA15 is a molecule that targets specifically BiPGRP78HSPA5. HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
CSN11085 Geldanamycin 30562-34-6 Geldanamycin is a natural existing HSP90 inhibitor with Kd of 12 M
CSN22828 Gedunin 2753-30-2 Gedunin is a Hsp90 inhibitor and exhibits anticancer and antimalarial activity.
CSN15732 Ganetespib 888216-25-9 Ganetespib is a unique triazolone-containing Hsp90 inhibitor with an IC50 of 4 nM in OSA 8 cells
CSN12347 Elesclomol 488832-69-5 Elesclomol an inhibitor of HSP90 is a potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells
CSN22799 EC 144 911397-80-3 EC 144 is a high affinity, potent and selective Hsp90 inhibitor with Ki of 0.2 nM and IC50 of 1.1 nM.
CSN13532 Dihydroberberine 483-15-8 Dihydroberberine, a natural product isolated and purified from the tubers of Corydalis decumbens (Thunb.) Pers., has anti-tumor activity. Dihydroberberine improves in vivo efficacy in terms of counteracting increased adiposity, tissue triglyceride accumulation, and insulin resistance in high-fat-fed rodents, thus is potential therapeutic reagents for type 2 diabetes treatment.
CSN18944 Debio 0932 1061318-81-7 Debio 0932 is a heat shock protein 90 (HSP90) inhibitor with strong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L).
CSN19190 CH5138303 959763-06-5 CH5138303 is an orally available Hsp90 inhibitor with Kd of 048 nM
CSN22743 CCT 018159 171009-07-7 CCT 018159 is a novel inhibitor of heat shock protein 90 (Hsp90) ATPase activity with IC50 of 5.7 μM.
CSN22011 Bimoclomol 130493-03-7 Bimoclomol is a heat shock protein coinducer, used for treatment of cardiovascular diseases.
CSN13441 BIIB021   848695-25-0 BIIB021 is an orally available fully synthetic small-molecule inhibitor of HSP90 with Ki and EC50 of 17 nM and 38 nM respectively
CSN12421 Luminespib 747412-49-3 AUY922 is a highly potent HSP90 inhibitor for HSP90 with IC50 of 13 nM 21 nM, weaker potency against the HSP90 family members GRP94 and TRAP-1.
CSN16920 Onalespib 912999-49-6 AT13387 is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells displays a long duration of anti-tumor activity
CSN18941 Apoptozole   1054543-47-3 Apoptozole is an inhibitor of heat shock protein 70 HSP70 and Hsc70 It induces caspase-dependent apoptosis
CSN16172 Alvespimycin 467214-20-6 Alvespimycin is a potent, water-soluble HSP90 inhibitor with IC50 of 62 nM.
CSN18284 Alvespimycin HCl 467214-21-7 Alvespimycin HCl is a potent, water-soluble HSP90 inhibitor with IC50 of 62 nM.
CSN17209 17-AAG 75747-14-7 17-AAG is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.
CSN18562 17-AAG HCl 911710-03-7 17-AAG HCl is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.
CSN13554 Eupalinolide B 877822-41-8
<< PREV 1 2 NEXT >>