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Cat. No.	Product Name	CAS No.	Information
CSN16304	XL888	1149705-71-4	XL888 is a specific and ATP-competitive Hsp90 inhibitor with IC50 of 24 nM
CSN13596	VER-50589	747413-08-7	VER-50589 is an isoxazole compound that inhibits Hsp90 with an IC50 value of 21 nM
CSN18335	VER-49009	558640-51-0	VER-49009 is a pyrazole compound that inhibits Hsp90 with an IC50 value of 47 nM
CSN13116	VER-155008	1134156-31-2	VER-155008 is a potent Hsp70 family inhibitor with IC50 of 05 M 26 M and 26 M in cell-free assays for HSP70 HSC70 and GRP78 respectively 100-fold selectivity over HSP90
CSN20345	TRC051384	867164-40-7	TRC051384 is a inducer of Hsp70
CSN20344	TRC051384 HCl	1333327-56-2	TRC051384 HCl is a potent inducer of HSP70 which can induce HSP70B mRNA expression.
CSN12051	Teprenone	6809-52-5	Teprenone is used as an anti-ulcer drug, a cardioprotective agent, a hepatoprotective agent, a nephroprotective agent, a neuroprotective agent and a Hsp70 inducer.
CSN22232	TAS-116	1260533-36-5	TAS-116 is a potent and selective HSP90 inhibitor with Kis of 347 nM 213 nM respectively
CSN16517	SNX-2112	908112-43-6	SNX-2112 is a potent synthetic heat shock protein 90 HSP90 inhibitor with an IC50 of 092 M for K562 cells
CSN18481	Retaspimycin	857402-23-4	Retaspimycin is a small-molecule inhibitor of heat shock protein 90 HSP90 with antiproliferative and antineoplastic activities
CSN18482	Retaspimycin HCl	857402-63-2	Retaspimycin HCl is the HCl salt of a small-molecule inhibitor of heat shock protein 90 (HSP90) with antiproliferative and antineoplastic activities.
CSN15760	PU-WS13	1454619-14-7	PU-WS13 is a potent Grp94-specific Hsp90 inhibitor of the purine scaffold class
CSN16046	PU-H 71	873436-91-0	PU-H71 is a potent Hsp90 inhibitor with IC50 of 50 nM
CSN18943	PU-H 71 HCl	2095432-24-7	PU-H71 HCl is a potent Hsp90 inhibitor with IC50 of 50 nM.
CSN11740	Platycodin D	58479-68-8	Platycodin D is a natural product isolated and purified from the root of Platycodon grandiflorum., which may stimulate TNF- synthesis or inhibit degradation of TNF- mRNA, and is an Hsp90 inhibitor which disrupting the co-chaperone interaction of Hsp90cell division cycle protein 37 (Cdc37) and subsequently degrading multiple Hsp90 client proteins without the feedback increase of Hsp70.
CSN17514	PF-04929113 Mesylate	1173111-67-5	PF-04929113 mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM
CSN16541	PF-04929113	908115-27-5	PF-04929113 is a potent and selective HSP90 inhibitor with Kd of 41 nM and induces Her-2 degradation with IC50 of 37 nM
CSN15852	HSP990	934343-74-5	NVP-HSP990 is a potent and selective HSP90 inhibitor for HSP90 with IC50 of 06 nM08 nM
CSN17190	NVP-BEP800	847559-80-2	NVP-BEP800 is a fully synthetic HSP90 inhibitor with IC50 of 58 nM exhibits 70-fold selectivity against Hsp90 family members Grp94 and Trap-1
CSN16765	NMS-E973	1253584-84-7	NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of 10 nM for Hsp90 binding no activiy against a panel of 52 diverse protein kinases
CSN17387	ML346	100872-83-1	ML346 is an activator of Hsp70 with EC50 of 4600 nM in HeLa cell toxicity assay
CSN21425	MKT-077	147366-41-4	MKT-077 FJ-776 is a water-soluble rhodacyanine dye with antitumor activity It can bind to Hsp70 family member mortalin-2 and inhibit its interactions with p53
CSN22959	Macbecin I	73341-72-7	Macbecin I is a Hsp90 inhibitor with IC50 of 2 μM.
CSN16562	KW-2478	819812-04-9	KW-2478 is a nonansamycin HSP90 inhibitor with IC50 of 38 nM
CSN18942	KRIBB11	342639-96-7	KRIBB11 is an inhibitor of heat shock factor HSF inhibitor with IC50 of 12 M
CSN15324	Kongensin A	885315-96-8	Kongensin A, a natural product isolated and purified from the herbs of Croton cascarilloides, is an effective heat shock protein 90 (HSP90) inhibitor that has potential anti-necroptosis and anti-inflammation applications.
CSN17321	KNK437	218924-25-5	KNK437 is a pan-HSP inhibitor which inhibits the synthesis of inducible HSPs including HSP105 HSP72 and HSP40
CSN22600	JG98	1456551-16-8	JG-98, an allosteric heat shock protein 70 (Hsp70) inhibitor which shows anti-cancer activities affecting both cancer cells and tumor-associated macrophages.
CSN22089	HSP70-IN-1	1268273-90-0	HSP70-IN-1 is a heat shock protein (HSP) inhibitor.
CSN19076	HA15	1609402-14-3	HA15 is a molecule that targets specifically BiPGRP78HSPA5. HA15 displays anti-cancerous activity on all melanoma cells tested, including cells isolated from patients and cells that developed resistance to BRAF inhibitors.
CSN24783	Grp94 Inhibitor-1	2234897-35-7	Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor with an IC50 value of 2 nM, and over 1000-fold selectivity to Grp94 against Hsp90α[1].
CSN11085	Geldanamycin	30562-34-6	Geldanamycin is a natural existing HSP90 inhibitor with Kd of 12 M
CSN22828	Gedunin	2753-30-2	Gedunin is a Hsp90 inhibitor and exhibits anticancer and antimalarial activity.
CSN15732	Ganetespib	888216-25-9	Ganetespib is a unique triazolone-containing Hsp90 inhibitor with an IC50 of 4 nM in OSA 8 cells
CSN13554	Eupalinolide B	877822-41-8	Eupalinolide A is a natural product isolated and purified from the herbs of Eupatorium lindleyanum DC.
CSN12347	Elesclomol	488832-69-5	Elesclomol an inhibitor of HSP90 is a potent oxidative stress inducer that elicits pro-apoptosis events among tumor cells
CSN22799	EC 144	911397-80-3	EC 144 is a high affinity, potent and selective Hsp90 inhibitor with Ki of 0.2 nM and IC50 of 1.1 nM.
CSN13532	Dihydroberberine	483-15-8	Dihydroberberine, a natural product isolated and purified from the tubers of Corydalis decumbens (Thunb.) Pers., has anti-tumor activity. Dihydroberberine improves in vivo efficacy in terms of counteracting increased adiposity, tissue triglyceride accumulation, and insulin resistance in high-fat-fed rodents, thus is potential therapeutic reagents for type 2 diabetes treatment.
CSN18944	Debio 0932	1061318-81-7	Debio 0932 is a heat shock protein 90 (HSP90) inhibitor with strong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L).
CSN19190	CH5138303	959763-06-5	CH5138303 is an orally available Hsp90 inhibitor with Kd of 048 nM
CSN22743	CCT 018159	171009-07-7	CCT 018159 is a novel inhibitor of heat shock protein 90 (Hsp90) ATPase activity with IC50 of 5.7 μM.
CSN22011	Bimoclomol	130493-03-7	Bimoclomol is a heat shock protein coinducer, used for treatment of cardiovascular diseases.
CSN13441	BIIB021	848695-25-0	BIIB021 is an orally available fully synthetic small-molecule inhibitor of HSP90 with Ki and EC50 of 17 nM and 38 nM respectively
CSN12421	Luminespib	747412-49-3	AUY922 is a highly potent HSP90 inhibitor for HSP90 with IC50 of 13 nM 21 nM, weaker potency against the HSP90 family members GRP94 and TRAP-1.
CSN16920	Onalespib	912999-49-6	AT13387 is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells displays a long duration of anti-tumor activity
CSN18941	Apoptozole	1054543-47-3	Apoptozole is an inhibitor of heat shock protein 70 HSP70 and Hsc70 It induces caspase-dependent apoptosis
CSN16172	Alvespimycin	467214-20-6	Alvespimycin is a potent, water-soluble HSP90 inhibitor with IC50 of 62 nM.
CSN18284	Alvespimycin HCl	467214-21-7	Alvespimycin HCl is a potent, water-soluble HSP90 inhibitor with IC50 of 62 nM.
CSN17209	17-AAG	75747-14-7	17-AAG is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.
CSN18562	17-AAG HCl	911710-03-7	17-AAG HCl is a potent HSP90 inhibitor with IC50 of 5 nM, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells.

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