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HMGCR

HMGCR

Cat. No. Product Name CAS No. Information
CSN19944 Swertiamarine   17388-39-5 Swertiamarine is a naturally occuring secoiridoid glycoside which could inhibit HMG-CoA reductase activity
CSN19036 SR-12813 126411-39-0 SR-12813 is a pregnane X receptor PXR agonist and HMG-CoA reductase inhibitor with an IC50 of 850 nM
CSN11928 Simvastatin Ammonium 139893-43-9 Simvastatin ammonium is an HMG-CoA reductase inhibitor
CSN11927 Simvastatin   79902-63-9 Simvastatin a specific and a lovastatin similar HMG-CoA reductase inhibitor with Ki value of 0.1-0.2 nM, used to treat hypercholesterolemia.
CSN11865 Rosuvastatin   287714-41-4 Rosuvastatin is a synthetic and highly effective statin-class HMG-CoA reductase inhibitor with IC50 of 11 nM
CSN12558 Rosuvastatin Calcium   147098-20-2 Rosuvastatin Calcium is a competitive and synthetic HMG-CoA reductase inhibitor with IC50 value of 11 nM
CSN12298 Pravastatin Sodium 81131-70-6 Pravastatin Sodium is a competitive HMG-CoA reductase inhibitor with IC50 value of 56 M
CSN12933 Pravastatin 81093-37-0 Pravastatin is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 56 M
CSN11236 Pitavastatin 147511-69-1 Pitavastatin is a potent HMG-CoA reductase inhibitor and inhibits cholesterol synthesis from acetic acid with an IC50 of 58 nM in a human liver cancer cell line HepG2
CSN11738 Pitavastatin Calcium   147526-32-7 Pitavastatin Calcium is a potent and competitive inhibitor of HMG-CoA reductase with Ki value of 1.7nM, which can block cholesterol synthesis.
CSN22122 Monacolin J 79952-42-4 Monacolin J is an inhibitor of cholesterol biosynthesis, and inhibits the activity of HMG-CoA reductase.
CSN11434 Mevastatin   73573-88-3 Mevastatin is the first discovered statin-class HMG-CoA reductase inhibitor used as a cholesterol-lowering agent isolated from Penicillium citinium
CSN19379 Meglutol 503-49-1 Meglutol is an antilipemic agent which lowers cholesterol triglycerides serum beta-lipoproteins and phospholipids and inhibits the activity of hydroxymethylglutarryl CoA reductases which is the rate limiting enzyme in the biosynthesis of cholesterol
CSN11335 Lovastatin   75330-75-5 Lovastatin is a HMG-CoA reductase used to treat high blood cholesterol and reduce the risk of cardiovascular disease, a naturally occuring fungal metabolite.
CSN13091 Fluvastatin Sodium   93957-55-2 Fluvastatin Sodium is a synthetic indole-heptanoic-acid-derived inhibitor of hepatic HMG-CoA reductase with IC50 of 8 nM
CSN12947 Fluvastatin 93957-54-1 Fluvastatin inhibits HMG-CoA reductase activity with IC50 of 8 nM
CSN10667 Clinofibrate   30299-08-2 Clinofibrate is a HMG-CoA reductase inhibitor with IC50 value of 470 M which can reduce plasma cholesterol levels and shows antihyperlipidemic effects
CSN12529 Atorvastatin 134523-00-5 Atorvastatin is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol
CSN12530 Atorvastatin Hemicalcium   134523-03-8 Atorvastatin Hemicalcium is a potent HMG-CoA reductase inhibitor with IC50 value of 8 nM
CSN11493 alpha-Asarone   2883-98-9 alpha-Asarone is a naturally occuring inhibitor of both HMG-CoA reductase IC50 3 mM and certain isoforms of the cytochrome P450 superfamily of enzymes IC50 552 and 652 gml for CYP2D6 and CYP3A4 respectively with neuroprotective anti-oxidative anticonvulsive and cognitive enhancing action
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