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Histone Demethylase

Histone Demethylase

Cat. No. Product Name CAS No. Information
CSN12941 IOX1   5852-78-8 IOX1 is the broad-spectrum inhibitor of 2OG oxygenases and its IC50 for KDM4AKDM3A and KDM4CKDM6BKDM2AKDM4E are 0601 M and 06 M16 M18 M23 M
CSN23888 GSK 467 1628332-52-4 GSK467 is a selective KDM5 inhibitor with Ki of 10 nM. It has no measurable inhibitory effects toward other JmJ family members.
CSN19201 GSK-LSD1 2HCl   1821798-25-7 GSK-LSD1 2HCl is a selective LSD1 inhibitor with IC50 of 16 nM.
CSN19181 GSK-J4 HCl   1797983-09-5 GSK-J4 HCl is selective inhibitor of jumonji H3K27 demethylase. It can attenuate lipopolysaccharide (LPS)-induced proinflammatory cytokine production.
CSN19243 CPI-455 HCl   2095432-28-1 CPI-455 HCl is an inhibitor of KDM5 It can elevate global levels of H3K4 trimethylation H3K4me3 and decrease the number of DTPs in multiple cancer cell line models
CSN21279 AS-8351   796-42-9 AS8351 is a selective inhibitor of histone demethylase KDM5B JARID1B via competing for the chelated iron KDM5B needs and it can act as an iron chelator
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