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Hes genes code nuclear proteins that suppress transcription. This protein belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Hes genes are mammalian homologs of the Drosophila genes hairy and Enhancer of split [E(spl)]. There are seven members in the Hes family (Hes1-7), although Hes4 is absent in the mouse genome (Table 1). Hes genes encode nuclear proteins that repress transcription both actively and passively.


Cat. No. Product Name CAS No. Information
CSN24256 JI051 2234281-75-3 JI051 is Hes1 inhibitor which can impair the ability of Hes1 to repress transcription.
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