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HDAC

HDAC

Cat. No. Product Name CAS No. Information
CSN11991 Vorinostat     149647-78-9 Vorinostat is an HDAC1/3 inhibitor with IC50 of ~10 nM.
CSN22927 TH34 2196203-96-8 TH34 is a potent HDAC6/8/10 inhibitor that induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines.
CSN19743 Sulforaphane Racemate 4478-93-7 Sulforaphane a natural product isolated and purified from the seeds of Brassica oleracea L var botrytis L with neuroprotective anti-inflammatory and antitumor effects inhibits TPA-induced NF-B activation and COX-2 expression in MCF-10A cells by blocking two distinct signaling pathways mediated by ERK12-IKK and NAK-IKK
CSN24467 SIS17 2374313-54-7 SIS17 is a specific HDAC11 inhibitor with IC50 value of 0.83μM for inhibition of the demyristoylation HDAC11 substrate, serine hydroxymethyl transferase 2.
CSN23627 Sinapinic Acid   530-59-6 Sinapinic Acid inhibits collagen-induced human platelet aggregation by up to 70 in vitro with IC50 of 103 mM is a phenylpropanoid hydroxycinnamic acid with diverse biological activities
CSN13496 Romidepsin 128517-07-7 Romidepsin is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.
CSN21402 Pomiferin 572-03-2 Pomiferin, a flavonoid from the fruits of Maclura pomifera, acts as an potential inhibitor of HDAC, with an IC50 of 1.05 M, and also potently inhibits mTOR (IC50, 6.2 M).
CSN16486 Pimelic Diphenylamide 106   937039-45-7 Pimelic diphenylamide 106 is an inhibitor of class I HDAC with IC50 for HDAC1, HDAC2, and HDAC3 of 150 nM, 760nM, and 370 nM, respectively.
CSN12566 Gallic Acid   149-91-7 Gallic acid is an organic acid that found in a variety of foods and herbs with effective antioxidant activity.
CSN11480 Entinostat     209783-80-2 Entinostat strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM.
CSN12488 CI-994 112522-64-2 CI-994 is an inhibitor of HDAC1 with IC50 of 0.57 M with anti-tumor effect. It can cause G1 cell cycle arrest.
CSN21754 Biphenyl-4-sulfonyl Chloride   1623-93-4 Biphenyl-4-sulfonyl chloride is an inhibitor of HDAC and it has synthetic applications in palladium-catalyzed desulfitative C-arylation.
CSN27278 ACY-775   1375466-18-4 ACY-775 is a potent and selective inhibitor of the of histone deacetylase 6 (HDAC6) with an IC50 of 7.5 nM.
CSN23643 4-Phenylbutanoic acid 1821-12-1 4-Phenylbutanoic acid is an inhibitor of HDAC which can regulate gene transcription with anti-tumor and neuroprotective effects
CSN19518 4-Hydroxybenzoic Acid   99-96-7 4-Hydroxybenzoic acid, a natural product isolated and purified from the herbs of Rhodiola crenulata, positively regulates the expression of gum cluster to promote EPS production in PXO99A, and its derivatives have potential to as pan-HDAC inhibitors with anticancer properties.
CSN19744 (R)-Sulforaphane 142825-10-3 (R)-Sulforaphane, a natural product isolated and purified from brocoli, is a promising potential chemopreventitive agent in bladder cancer.
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