Welcome to CSNpharm! For Research Use Only!
Home +1-708-781-1677 sales@csnpharm.com    

HDAC

HDAC

Cat. No. Product Name CAS No. Information
CSN11991 Vorinostat       149647-78-9 Vorinostat is an HDAC1/3 inhibitor with IC50 of ~10 nM.
CSN13138 Valproic Acid   99-66-1 Valproic acid is a histone deacetylase HDAC inhibitor with IC50 of 10 M in Hela cell with anticancer effect It can be used in the treatment of epilepsy and bipolar disorder
CSN17250 UF010   537672-41-6 UF010 is a selective inhibitor of HDAC3 2 1 and 8 with IC50s of 006 M 01 M 05 M and 15 M respectively
CSN22526 Tucidinostat   1616493-44-7 Tucidinostat is an inhibitor of HDACenzymes class I (HDAC123) and class IIb (HDAC10) inhibitor withIC50s of 95, 160, 67 and 78 nM, espectively.
CSN17162 Tubastatin A 1252003-15-8 Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM and is selective1000-fold more against all other isozymes except HDAC857-fold more
CSN15899 TMP269 1314890-29-3 TMP269 is an inhibitor of class IIa HDAC with IC50 of 157 nM 97 nM 43 nM and 23 nM for HDAC4 HDAC5 HDAC7 and HDAC9 respectively
CSN11945 Sodium Butyrate   156-54-7 Sodium butyrate is a histone deacetylase HDAC inhibitor with IC50s are 03 mM 04 mM 03 mM for HDAC1 2 and 7 respectively
CSN24467 SIS17 2374313-54-7 SIS17 is a specific HDAC11 inhibitor with IC50 value of 0.83μM for inhibition of the demyristoylation HDAC11 substrate, serine hydroxymethyl transferase 2.
CSN13123 Scriptaid 287383-59-9 Scriptaid is an inhibitor of HDAC with greater effect on acetylated H4
CSN13835 Santacruzamate A   1477949-42-0 Santacruzamate A is an inhibitor of HDAC2 with IC50 of 119 pM
CSN13496 Romidepsin     128517-07-7 Romidepsin is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively.
CSN18796 RGFP966 Racemate     1396841-57-8 RGFP966 is an HDAC3 inhibitor with IC50 of 008 M in cell-free assay exhibits 200-fold selectivity over other HDAC
CSN13881 Remodelin 949912-58-7 Remodelin is a potent and selective inhibitor of the acetyl-transferase protein NAT10
CSN13125 PTACH 848354-66-5 PTACH is a SAHA-based inhibitor of human HDAC PTACH exerts potent growth inhibition against various human cancer cells with EC50 values ranging from 1 to 10 M
CSN16063 Pracinostat       929016-96-6 Pracinostat is a potent pan-HDAC inhibitor with IC50 of 40-140 nM with exception for HDAC6 and has no activity against the class III isoenzyme SIRT I.
CSN21402 Pomiferin 572-03-2 Pomiferin, a flavonoid from the fruits of Maclura pomifera, acts as an potential inhibitor of HDAC, with an IC50 of 1.05 M, and also potently inhibits mTOR (IC50, 6.2 M).
CSN16486 Pimelic Diphenylamide 106   937039-45-7 Pimelic diphenylamide 106 is an inhibitor of class I HDAC with IC50 for HDAC1, HDAC2, and HDAC3 of 150 nM, 760nM, and 370 nM, respectively.
CSN18939 Pimelic Diphenylamide 106 Analog 2070015-24-4 Pimelic diphenylamide 106 Analog is an analog of Pimelic Diphenylamide 106 with unknown biological activity. Pimelic Diphenylamide 106 is a class I HDAC inhibitor, demonstrating no activity against class II HDACs. 106 is a slow, tight-binding inhibitor of HDACs 1, 2, and 3 with preference toward HDAC3 with Ki of approximately 14 nm, 15 times lower than the Ki for HDAC1.
CSN16819 PCI-34051 950762-95-5 PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay It has greater than 200-fold selectivity over HDAC1 and 6 more than 1000-fold selectivity over HDAC2 3 and 10
CSN15819 PCI-24781 783355-60-2 PCI-24781 is a pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8.
CSN12908 Panobinostat       404950-80-7 Panobinostat is a broad-spectrum HDAC inhibitor with IC50 of 5 nM in a cell-free assay.
CSN17253 NKL 22 537034-15-4 NKL 22 is a HDAC inhibitor The value of IC 50 is 78 uM
CSN16017 Mocetinostat 726169-73-9 Mocetinostat is an inhibitor of HDAC1 (IC50 0.15 M), HDAC2 (IC50 0.29 M) and HDAC3 (IC50 1.66 M).
CSN16577 ITF2357 HCl H2O   732302-99-7 ITF2357 HCl is a potent HDAC inhibitor for Maize HD2, HD1-B and HD1-A with IC50 of 10 nM, 7.5 nM and 16 nM, respectively.
CSN18800 HPOB 1429651-50-2 HPOB is a selective inhibitor of HDAC6 with IC50 of 56 nM
CSN20189 HDAC Inhibitor C001 1609389-52-7 HDAC inhibitor C001 is an inhibitor of HDACs with IC50 of 4 nM HDAC1 15 nM HDAC2 114 nM HDAC3 and can increase Gata2 expression which may be useful in treatment of Gata2-deficiency-associated diseases including leukemia and other blood cell disorders
CSN18301 Givinostat 497833-27-9 Givinostat is a potent HDAC inhibitor for Maize HD2, HD1-B and HD1-A with IC50 of 10 nM, 7.5 nM and 16 nM,respectively.
CSN18083 Givinostat HCl 199657-29-9 Givinostat hydrochloride is a potent HDAC inhibitor for Maize HD2, HD1-B and HD1-A with IC50 of 10 nM, 7.5 nM and 16 nM, respectively.
CSN12566 Gallic Acid   149-91-7 Gallic acid is an organic acid that found in a variety of foods and herbs with effective antioxidant activity.
CSN11480 Entinostat       209783-80-2 Entinostat strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM.
CSN16783 Divalproex Sodium   76584-70-8 Divalproex sodium is a HDAC inhibitor used in the treatment for epilepsy
CSN15774 Dacinostat 404951-53-7 Dacinostat is a HDAC inhibitor with IC50 of 32 nM which can activate the p21 promoter.
CSN16258 CUDC-907 1339928-25-4 CUDC-907 is a dual PI3K and HDAC inhibitor for PI3Kα and HDAC1/2/3/10 with IC50 of 19 nM and 1.7 nM/5 nM/1.8 nM/2.8 nM, respectively.
CSN20226 CM-272 1846570-31-7 CM-272 is a potent selective and reversible dual small molecule against G9a and DNMTs activity
CSN13794 Citarinostat 1316215-12-9 Citarinostat selectively inhibits HDAC6 with IC50 of 4 nM. It can also inhibit HDAC3 (IC50 76 nM).
CSN12488 CI-994 112522-64-2 CI-994 is an inhibitor of HDAC1 with IC50 of 0.57 M with anti-tumor effect. It can cause G1 cell cycle arrest.
CSN16989 Chidamide 743420-02-2 Chidamide is a class I HDAC inhibitor with IC50s of 9516067733 nM for HDAC1238, also inhibiting HDAC1011 (IC5078432 nM) and showing no inhibition on HDAC45796 (IC50 30 M).
CSN13836 CAY10603 1045792-66-2 CAY10603 is a selective inhibitor of HDAC6 with IC50 of 2 pM
CSN24145 BRD 4354 Ditrifluoroacetate N/A BRD 4354 Ditrifluoroacetate is an inhibitor of HDAC5 and HDAC9 with IC50s of 0.85 and 1.88 μM respectively.
CSN17249 BML-210 537034-17-6 BML-210 is the HDAC inhibitor and its mechanism of action has not been characterized
CSN21754 Biphenyl-4-sulfonyl Chloride   1623-93-4 Biphenyl-4-sulfonyl chloride is an inhibitor of HDAC and it has synthetic applications in palladium-catalyzed desulfitative C-arylation.
CSN17264 BG45   926259-99-6 BG45 is a selective inhibitor for HDAC3 with IC50 of 289 nM
CSN11550 Belinostat(Random Configuration)   414864-00-9 Belinostat is a HDAC inhibitor with IC50 of 27 nM in a cell-free assay, with activity demonstrated in cisplatin-resistant tumors.
CSN13429 AR-42 935881-37-1 AR-42 is an inhibitor of HDAC with IC50 30 nM.
CSN19745 Apicidin 183506-66-3 Apicidin is a potent histone deacetylase HDAC inhibitor with antiangiogenic and anti-invasive activity which blocks proliferation of human stomach and breast cancer cells and induces apoptosis and autophagy in human oral squamous carcinoma cells
CSN17328 ACY-738 1375465-91-0 ACY-738 inhibits HDAC6 with IC50 value of 17 nM
CSN19518 4-Hydroxybenzoic Acid   99-96-7 4-Hydroxybenzoic acid, a natural product isolated and purified from the herbs of Rhodiola crenulata, positively regulates the expression of gum cluster to promote EPS production in PXO99A, and its derivatives have potential to as pan-HDAC inhibitors with anticancer properties.
CSN19744 (R)-Sulforaphane 142825-10-3 (R)-Sulforaphane, a natural product isolated and purified from brocoli, is a promising potential chemopreventitive agent in bladder cancer.
CSN24175 JAK/HDAC-IN-1 2284621-75-4
<< PREV 1 2 3 NEXT >>