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HDAC
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN11991 | Vorinostat | 149647-78-9 | Vorinostat is an HDAC1/3 inhibitor with IC50 of ~10 nM. |
| CSN13138 | Valproic Acid | 99-66-1 | Valproic acid is a histone deacetylase HDAC inhibitor with IC50 of 10 M in Hela cell with anticancer effect It can be used in the treatment of epilepsy and bipolar disorder |
| CSN17250 | UF010 | 537672-41-6 | UF010 is a selective inhibitor of HDAC3 2 1 and 8 with IC50s of 006 M 01 M 05 M and 15 M respectively |
| CSN22526 | Tucidinostat | 1616493-44-7 | Tucidinostat is an inhibitor of HDACenzymes class I (HDAC123) and class IIb (HDAC10) inhibitor withIC50s of 95, 160, 67 and 78 nM, espectively. |
| CSN17162 | Tubastatin A | 1252003-15-8 | Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM and is selective1000-fold more against all other isozymes except HDAC857-fold more |
| CSN15899 | TMP269 | 1314890-29-3 | TMP269 is an inhibitor of class IIa HDAC with IC50 of 157 nM 97 nM 43 nM and 23 nM for HDAC4 HDAC5 HDAC7 and HDAC9 respectively |
| CSN11945 | Sodium Butyrate | 156-54-7 | Sodium butyrate is a histone deacetylase HDAC inhibitor with IC50s are 03 mM 04 mM 03 mM for HDAC1 2 and 7 respectively |
| CSN13123 | Scriptaid | 287383-59-9 | Scriptaid is an inhibitor of HDAC with greater effect on acetylated H4 |
| CSN13835 | Santacruzamate A | 1477949-42-0 | Santacruzamate A is an inhibitor of HDAC2 with IC50 of 119 pM |
| CSN13496 | Romidepsin | 128517-07-7 | Romidepsin is a potent HDAC1 and HDAC2 inhibitor with IC50 of 36 nM and 47 nM, respectively. |
| CSN18796 | RGFP966 Racemate | 1396841-57-8 | RGFP966 is an HDAC3 inhibitor with IC50 of 008 M in cell-free assay exhibits 200-fold selectivity over other HDAC |
| CSN13881 | Remodelin | 949912-58-7 | Remodelin is a potent and selective inhibitor of the acetyl-transferase protein NAT10 |
| CSN18839 | Quisinostat 2HCl | 875320-31-3 | Quisinostat dihydrochloride is a second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 011 nM in a cell-free assay modest potent to HDACs 2 4 10 and 11 greater than 30-fold selectivity against HDACs 3 5 8 and 9 and lowest potency to HDACs 6 and 7 |
| CSN13125 | PTACH | 848354-66-5 | PTACH is a SAHA-based inhibitor of human HDAC PTACH exerts potent growth inhibition against various human cancer cells with EC50 values ranging from 1 to 10 M |
| CSN16063 | Pracinostat | 929016-96-6 | Pracinostat is a potent pan-HDAC inhibitor with IC50 of 40-140 nM with exception for HDAC6 and has no activity against the class III isoenzyme SIRT I. |
| CSN21402 | Pomiferin | 572-03-2 | Pomiferin, a flavonoid from the fruits of Maclura pomifera, acts as an potential inhibitor of HDAC, with an IC50 of 1.05 M, and also potently inhibits mTOR (IC50, 6.2 M). |
| CSN16486 | Pimelic Diphenylamide 106 | 937039-45-7 | Pimelic diphenylamide 106 is an inhibitor of class I HDAC with IC50 for HDAC1, HDAC2, and HDAC3 of 150 nM, 760nM, and 370 nM, respectively. |
| CSN18939 | Pimelic Diphenylamide 106 Analog | 2070015-24-4 | Pimelic diphenylamide 106 Analog is an analog of Pimelic Diphenylamide 106 with unknown biological activity. Pimelic Diphenylamide 106 is a class I HDAC inhibitor, demonstrating no activity against class II HDACs. 106 is a slow, tight-binding inhibitor of HDACs 1, 2, and 3 with preference toward HDAC3 with Ki of approximately 14 nm, 15 times lower than the Ki for HDAC1. |
| CSN16819 | PCI-34051 | 950762-95-5 | PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay It has greater than 200-fold selectivity over HDAC1 and 6 more than 1000-fold selectivity over HDAC2 3 and 10 |
| CSN15819 | PCI-24781 | 783355-60-2 | PCI-24781 is a pan-HDAC inhibitor mostly targeting HDAC1 with Ki of 7 nM, modest potent to HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. |
| CSN12908 | Panobinostat | 404950-80-7 | Panobinostat is a broad-spectrum HDAC inhibitor with IC50 of 5 nM in a cell-free assay. |
| CSN17253 | NKL 22 | 537034-15-4 | NKL 22 is a HDAC inhibitor The value of IC 50 is 78 uM |
| CSN16017 | Mocetinostat | 726169-73-9 | Mocetinostat is an inhibitor of HDAC1 (IC50 0.15 M), HDAC2 (IC50 0.29 M) and HDAC3 (IC50 1.66 M). |
| CSN16577 | ITF2357 HCl H2O | 732302-99-7 | ITF2357 HCl is a potent HDAC inhibitor for Maize HD2, HD1-B and HD1-A with IC50 of 10 nM, 7.5 nM and 16 nM, respectively. |
| CSN18800 | HPOB | 1429651-50-2 | HPOB is a selective inhibitor of HDAC6 with IC50 of 56 nM |
| CSN20189 | HDAC Inhibitor C001 | 1609389-52-7 | HDAC inhibitor C001 is an inhibitor of HDACs with IC50 of 4 nM HDAC1 15 nM HDAC2 114 nM HDAC3 and can increase Gata2 expression which may be useful in treatment of Gata2-deficiency-associated diseases including leukemia and other blood cell disorders |
| CSN18301 | Givinostat | 497833-27-9 | Givinostat is a potent HDAC inhibitor for Maize HD2, HD1-B and HD1-A with IC50 of 10 nM, 7.5 nM and 16 nM,respectively. |
| CSN18083 | Givinostat HCl | 199657-29-9 | Givinostat hydrochloride is a potent HDAC inhibitor for Maize HD2, HD1-B and HD1-A with IC50 of 10 nM, 7.5 nM and 16 nM, respectively. |
| CSN12566 | Gallic Acid | 149-91-7 | Gallic acid is an organic acid that found in a variety of foods and herbs with effective antioxidant activity. |
| CSN11480 | Entinostat | 209783-80-2 | Entinostat strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM. |
| CSN18647 | Droxinostat | 99873-43-5 | Droxinostat is an inhibitor of HDAC3 HDAC6 and HDAC8 with IC50 of 169 247 and 146 M respectively |
| CSN16783 | Divalproex Sodium | 76584-70-8 | Divalproex sodium is a HDAC inhibitor used in the treatment for epilepsy |
| CSN15774 | Dacinostat | 404951-53-7 | Dacinostat is a HDAC inhibitor with IC50 of 32 nM which can activate the p21 promoter. |
| CSN16258 | CUDC-907 | 1339928-25-4 | CUDC-907 is a dual PI3K and HDAC inhibitor for PI3Kα and HDAC1/2/3/10 with IC50 of 19 nM and 1.7 nM/5 nM/1.8 nM/2.8 nM, respectively. |
| CSN20226 | CM-272 | 1846570-31-7 | CM-272 is a potent selective and reversible dual small molecule against G9a and DNMTs activity |
| CSN13794 | Citarinostat | 1316215-12-9 | Citarinostat selectively inhibits HDAC6 with IC50 of 4 nM. It can also inhibit HDAC3 (IC50 76 nM). |
| CSN12488 | CI-994 | 112522-64-2 | CI-994 is an inhibitor of HDAC1 with IC50 of 0.57 M with anti-tumor effect. It can cause G1 cell cycle arrest. |
| CSN16989 | Chidamide | 743420-02-2 | Chidamide is a class I HDAC inhibitor with IC50s of 9516067733 nM for HDAC1238, also inhibiting HDAC1011 (IC5078432 nM) and showing no inhibition on HDAC45796 (IC50 30 M). |
| CSN13836 | CAY10603 | 1045792-66-2 | CAY10603 is a selective inhibitor of HDAC6 with IC50 of 2 pM |
| CSN17249 | BML-210 | 537034-17-6 | BML-210 is the HDAC inhibitor and its mechanism of action has not been characterized |
| CSN21754 | Biphenyl-4-sulfonyl Chloride | 1623-93-4 | Biphenyl-4-sulfonyl chloride is an inhibitor of HDAC and it has synthetic applications in palladium-catalyzed desulfitative C-arylation. |
| CSN17264 | BG45 | 926259-99-6 | BG45 is a selective inhibitor for HDAC3 with IC50 of 289 nM |
| CSN11550 | Belinostat(Random Configuration) | 414864-00-9 | Belinostat is a HDAC inhibitor with IC50 of 27 nM in a cell-free assay, with activity demonstrated in cisplatin-resistant tumors. |
| CSN13429 | AR-42 | 935881-37-1 | AR-42 is an inhibitor of HDAC with IC50 30 nM. |
| CSN19745 | Apicidin | 183506-66-3 | Apicidin is a potent histone deacetylase HDAC inhibitor with antiangiogenic and anti-invasive activity which blocks proliferation of human stomach and breast cancer cells and induces apoptosis and autophagy in human oral squamous carcinoma cells |
| CSN17328 | ACY-738 | 1375465-91-0 | ACY-738 inhibits HDAC6 with IC50 value of 17 nM |
| CSN19518 | 4-Hydroxybenzoic Acid | 99-96-7 | 4-Hydroxybenzoic acid, a natural product isolated and purified from the herbs of Rhodiola crenulata, positively regulates the expression of gum cluster to promote EPS production in PXO99A, and its derivatives have potential to as pan-HDAC inhibitors with anticancer properties. |
| CSN19744 | (R)-Sulforaphane | 142825-10-3 | (R)-Sulforaphane, a natural product isolated and purified from brocoli, is a promising potential chemopreventitive agent in bladder cancer. |
| CSN24175 | JAK/HDAC-IN-1 | 2284621-75-4 |
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