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HCV

HCV

Cat. No. Product Name CAS No. Information
CSN17404 VX-222 1026785-59-0 VX-222 is a potent and selective inhibitor of HCV polymerase with IC50 of 094-12 M 153-fold less effective for mutant M423T and 108-fold less effective for mutant I482L
CSN19284 Voxilaprevir 1535212-07-7 Voxilaprevir is used for the treatment of Hepatitis C virus infection
CSN16632 VCH-916 1200133-34-1 VCH-916 is a nonnucleoside HCV NS5B polymerase inhibitor
CSN18586 Vaniprevir 923590-37-8 Vaniprevir is a non-covalent competitive inhibitor of the hepatitis C virus HCV NS34A protease
CSN19730 Uprifosbuvir 1496551-77-9 Uprifosbuvir is an uridine nucleotide analog HCV NS5B polymerase inhibitor.
CSN18806 TMC647055 Choline 1204416-97-6 TMC647055 choline is a cell-permeating selective HCV NS5B inhibitor eliciting a mean IC50 of 34 nM as assessed in the RdRp primer-dependent transcription assay
CSN12417 Telaprevir 402957-28-2 Telaprevir is a potent, selective, peptidomimetic inhibitor of the hepatitis C virus (HCV) NS3-4A serine protease (Ki7 nM, genotype 1a NS3-4A protease).
CSN16292 Tegobuvir 1000787-75-6 Tegobuvir is a non-nucleoside nonstructural protein (NS)5B polymerase inhibitor.
CSN16060 Simeprevir   923604-59-5 Simeprevir is an inhibitor of HCV NS34A protease with Ki of 0.36 nM and EC50 of 7.8 nM against viral replication.
CSN18867 SB-9200 942123-43-5 SB-9200 has a broad-spectrum antiviral activity against RNA viruses including hepatitis C virus HCV norovirus respiratory syncytial virus and influenza and has demonstrated activity against hepatitis B virus HBV in vitro and in vivo
CSN19678 Ruzasvir 1613081-64-3 Ruzasvir is a potent Pan-Genotype HCV NS5A inhibitor with Optimized activity against common resistance-associated polymorphisms
CSN17086 Ribavirin   36791-04-5 Ribavirin blocks nucleic acid synthesis and inhibits both RNA and DNA viruses. Ribavirin is a nucleoside antimetabolite antiviral agent.
CSN16818 R7128 940908-79-2 R7128 is a selective nucleoside analog inhibitor of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, with activity across all HCV genotypes.
CSN17374 PSI-7976 1190308-01-0 PSI-7976 the isomer of PSI-7977 is an inhibitor of HCV RNA replication in the HCV replicon assay EC50107 M
CSN21928 PSI-7409 1015073-42-3 PSI-7409 is the active 5′-triphosphate metabolite of PSI-7851 which is a selective and highly active nucleotide analog inhibitor of HCV.
CSN12940 PSI-6206   863329-66-2 PSI-6206 the deaminated derivative of PSI-6130 is a selective inhibitor of HCV NS5B polymerase and the EC50 for inhibition of HCV replicon is 100 M
CSN19731 Pibrentasvir   1353900-92-1 Pibrentasvir is a protease inhibitor potentially for the treatment of HCV infection
CSN11747 Peretinoin 81485-25-8 Peretinoin an acyclic retinoid can alter lipid metabolism and inhibit HCV RNA amplification and virus release
CSN15768 Paritaprevir   1216941-48-8 Paritaprevir is an inhibitor of NS3-4A serine protease that may be used for treatment of hepatitis C.
CSN15769 Ombitasvir   1258226-87-7 Ombitasvir is inhibitor of hepatitis C virus protein NS5A with EC50s of 082 pM to 193 pM against HCV genotypes 1 to 5
CSN18776 NM107   20724-73-6 NM107 is an inhibitor of HCV RNA replication with IC50 of 70 M
CSN20487 MK-8876 1426960-33-9 MK-8876 is a HCV NS5B Site D Inhibitor
CSN17832 MK-5172 Sodium 1425038-27-2 MK-5172 sodium is a P2-P4 quinoxaline macrocyclic HCV NS34a protease inhibitor currently in clinical development.
CSN17558 MK-5172 Potassium 1206524-86-8 MK-5172 potassium is a P2-P4 quinoxaline macrocyclic HCV NS34a protease inhibitor currently in clinical development.
CSN17729 MK-5172 Hydrate 1350462-55-3 MK-5172 is a P2-P4 quinoxaline macrocyclic HCV NS34a protease inhibitor currently in clinical development
CSN13898 MK-5172 1350514-68-9 MK-5172 inhibits Hepatitis C virus NS34a protease with Ki of 001 nM gt1b 001 nM gt1a 008 nM gt2a 015 nM gt2b 090 nM gt3a respectively
CSN13833 Ledipasvir   1256388-51-8 Ledipasvir is the hepatitis C virus NS5A inhibitor with EC50 of 34 pM and 4 pM against GT1a and GT1b replicon
CSN17899 Ledipasvir D-Tartrate 1502654-87-6 Ledipasvir D-tartrate is an inhibitor of the hepatitis C virus NS5A protein which is an experimental drug for the treatment of hepatitis C
CSN14312 Ladanein 10176-71-3 Ladanein is a phytochemicals inhibitor that is known to disrupt the interactions of core and other hepatitis C virus HCV proteins
CSN18891 KIN1408 1903800-11-2 KIN1408 is an antiviral small molecule compound as agonists of the RLR pathway
CSN22150 JTK-853 954389-09-4 JTK-853 is a novel non-nucleoside Hepatitis C Virus HCV polymerase inhibitor which shows effective antiviral activity in HCV replicon cells with EC50s of 038 and 0035 M in genotype 1a H77 and 1b Con1 strains respectively
CSN19807 IDX 184 1036915-08-8 IDX 184 is an RNA-directed RNA polymerase NS5B inhibitor potentially for the treatment of HCV infection
CSN20438 GSK2878175 1423007-82-2 GSK2878175 is a pan-genotypic non-nucleoside NS5B polymerase inhibitor potentially for the treatment of HCV infection
CSN20249 GSK-2336805 1256390-53-0 GSK-2336805 is a HCV NS5A inhibitor potentially for the treatment of HCV infection.
CSN20645 Glecaprevir 1365970-03-1 Glecaprevir is a NS 34A inhibitor potentially for the treatment of HCV.
CSN21653 furaprofen 67700-30-5 Furaprofen is an inhibitor of HCV replication and it is substantially more potent against genotype 1a and 1b replicons (EC50 ≈ 30 nM) than genotype 2a (EC50 ≈ 1 μM).
CSN17757 Elbasvir 1370468-36-2 Elbasvir is an inhibitor of nonstructural protein 5A NS5A of hepatitis C virus HCV It can be used to treat chronic HCV infection
CSN18471 Danoprevir 850876-88-9 Danoprevir, a peptidomimetic, is an inhibitor of the NS34A protease of hepatitis C virus (HCV) with IC50 of 0.2 nM - 3.5 nM.
CSN12990 Daclatasvir 1009119-64-5 Daclatasvir is a first-in-class, highly-selective oral HCV NS5A inhibitor.
CSN12832 Daclatasvir 2HCl   1009119-65-6 Daclatasvir 2HCl is a selective HCV NS5A inhibitor with EC50 of 9 pM - 50 pM.
CSN12581 Boceprevir 394730-60-0 Boceprevir is an HCV protease inhibitor (Ki14 nM) for the treatment of hepatitis C virus infection.
CSN20334 BMS-961955 1431328-92-5 BMS-961955 is an allosteric inhibitor of the hepatitis C virus NS5B polymerase
CSN17310 Asunaprevir   630420-16-5 Asunaprevir is an inhibitor of hepatitis C virus HCV NS3 protease
CSN19317 Artemisinin   63968-64-9 Artemisinin is an inhibitor of HCV subgenomic replicon. It widely used as anti-malarial drug.
CSN18276 Anguizole 442666-98-0 Anguizole is a small molecule inhibitor of HCV replication and alters NS4Bs subcellular distribution
CSN20627 Alisporivir 254435-95-5 Alisporivir is a cyclophilin inhibitor molecule with potent anti-hepatitis C virus (HCV) activity.
CSN22160 ACH-806 870142-71-5 ACH-806 is an NS4A antagonist which can inhibit Hepatitis C Virus HCV replication with an EC50 of 14 nM
CSN13704 ABT-333   1132935-63-7 ABT-333 is an inhibitor of the RNA-dependent RNA polymerase with IC50 range from 22 nM to 107 nM
CSN23603 4-Phenoxybenzylamine   107622-80-0 4-Phenoxybenzylamine can stabilize the NS3 protein in an inactive state with IC50 of 500 M
CSN25415 Mecarbinate 15574-49-9
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