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Guanylate Cyclase

Guanylate Cyclase

Cat. No. Product Name CAS No. Information
CSN19707 Vericiguat 1350653-20-1 Vericiguat targets soluble guanylate cyclase sGC and is used for treating heart failure
CSN15708 Riociguat   625115-55-1 Riociguat acts as stimulator of soluble guanylate cyclase sGC that is used to treat ipulmonary hypertension
CSN21165 Plecanatide 467426-54-6 Plecanatide is an oral guanylate cyclase C agonist acting locally in the gastrointestinal tract it is approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation CIC
CSN12227 YC-1   170632-47-0 Lificiguat is an acivator of guanylyl cyclase sGC and can bind to the heme-containing domain of the subunit with Kd of 06 M - 11 M
CSN18217 Cinaciguat 329773-35-5 Cinaciguat is the first of a class of soluble guanylate cyclase sGC activators in clinical development for acute decompensated heart failure
CSN18983 Cinaciguat HCl 646995-35-9 Cinaciguat hydrochloride is a potent soluble guanylate cyclase GC activator with EC50 of 15 nM in platelets
CSN21294 BM121307 137213-91-3 BM121307 is a guanylate cyclase activator that was in phase I development for the treatment of ischaemic heart disorders The research has been discontinued
CSN15709 BAY 41-2272 256376-24-6 BAY 41-2272 is an activator of guanylate cyclases (sGC).
CSN19827 Ataciguat 254877-67-3 Ataciguat is a potent guanylate cyclase activator potentially for the treatment of aortic valve stenosis
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