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GSK-3

GSK-3

Cat. No. Product Name CAS No. Information
CSN19500 TDZD-8 327036-89-5 TDZD-8, the derivative of thiadiazolidinone, is a selective inhibitor of GSK-3. It inhibits GSK-3 with IC50 of 2 M.
CSN16568 SB-415286   264218-23-7 SB-415286 is an ATP-competitive inhibitor of GSK3GSK3 with IC50 of 78 nM and Ki of 31 nM
CSN12268 SB-216763 280744-09-4 SB-216763 is potent and selective glycogen synthase kinase-3 GSK-3 inhibitor Ki 9 nM and competes with ATP
CSN22886 Lithium Carbonate 554-13-2 Lithium Carbonate inhibits GSK-3 in vivo.
CSN11250 Kenpaullone   142273-20-9 Kenpaullone is an ATP-competitive inhibitor of CDK1cyclin B (IC50 0.4 M), CDK2cyclin A (IC50 0.68 M), CDK5p25 (IC50 0.85 M), lymphocyte kinase (IC50 0.47 M) , and GSK-3 (C50 0.23 M).
CSN11201 Indirubin-3'-Monoxime 160807-49-8 Indirubin-3-monoxime is a powerful inhibitor of GSK-3 with IC50 of 22nM also inhibits CDK15 IC50 180100 nM
CSN17624 CP21R7 125314-13-8 CP21R7 is a slective inhibitor of GSK-3
CSN13470 CHIR-99021     252917-06-9 CHIR-99021 is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM, exhibiting > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases.
CSN19176 CHIR-99021 HCl 1797989-42-4 CHIR-99021 HCl is HCl of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM and shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2.
CSN19149 CHIR-99021 3HCl 1782235-14-6 CHIR-99021 3HCl is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM, showing > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases.
CSN20636 CHIR-98024 556813-39-9 CHIR-98014 is a reversible inhibitor of GSK3 and GSK3 with IC50 of 065 nM and 058 nM respectively
CSN23355 CHIR-98014 252935-94-7 CHIR-98014 CT98014 is highly selective aminopyrimidine-derivatived inhibitor of GSK-3 with IC50 of 650nM and 580nM for GSK-3 and GSK-3measured by kinase assays respectively and exhibits 1000-fold selectivity for GSK-3 over closely related kinases such as cdc2
CSN13082 Bikinin   188011-69-0 Bikinin acts as an ATP-competitive inhibitor of arabidopsis GSK-3 and effective activator of brassinosteroid BR signaling
CSN23598 5-Bromoindole   10075-50-0 5-bromoindole is an inhibitor ofglycogen synthase kinase 3 GSK-3 it can be used as important pharmaceutical chemical intermediate
CSN18742 1-Azakenpaullone 676596-65-9 1-Azakenpaullone is a potent and selective GSK-3 inhibitor with IC50 of 18 nM 100-fold selectivity over CDK1cyclin B and CDK5p25
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