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GSK-3
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN19500 | TDZD-8 | 327036-89-5 | TDZD-8, the derivative of thiadiazolidinone, is a selective inhibitor of GSK-3. It inhibits GSK-3 with IC50 of 2 M. |
| CSN16568 | SB-415286 | 264218-23-7 | SB-415286 is an ATP-competitive inhibitor of GSK3GSK3 with IC50 of 78 nM and Ki of 31 nM |
| CSN12268 | SB-216763 | 280744-09-4 | SB-216763 is potent and selective glycogen synthase kinase-3 GSK-3 inhibitor Ki 9 nM and competes with ATP |
| CSN22886 | Lithium Carbonate | 554-13-2 | Lithium Carbonate inhibits GSK-3 in vivo. |
| CSN11250 | Kenpaullone | 142273-20-9 | Kenpaullone is an ATP-competitive inhibitor of CDK1cyclin B (IC50 0.4 M), CDK2cyclin A (IC50 0.68 M), CDK5p25 (IC50 0.85 M), lymphocyte kinase (IC50 0.47 M) , and GSK-3 (C50 0.23 M). |
| CSN11201 | Indirubin-3'-Monoxime | 160807-49-8 | Indirubin-3-monoxime is a powerful inhibitor of GSK-3 with IC50 of 22nM also inhibits CDK15 IC50 180100 nM |
| CSN17624 | CP21R7 | 125314-13-8 | CP21R7 is a slective inhibitor of GSK-3 |
| CSN13470 | CHIR-99021 | 252917-06-9 | CHIR-99021 is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM, exhibiting > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases. |
| CSN19176 | CHIR-99021 HCl | 1797989-42-4 | CHIR-99021 HCl is HCl of CHIR-99021, which is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM and shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2. |
| CSN19149 | CHIR-99021 3HCl | 1782235-14-6 | CHIR-99021 3HCl is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM, showing > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases. |
| CSN20636 | CHIR-98024 | 556813-39-9 | CHIR-98014 is a reversible inhibitor of GSK3 and GSK3 with IC50 of 065 nM and 058 nM respectively |
| CSN23355 | CHIR-98014 | 252935-94-7 | CHIR-98014 CT98014 is highly selective aminopyrimidine-derivatived inhibitor of GSK-3 with IC50 of 650nM and 580nM for GSK-3 and GSK-3measured by kinase assays respectively and exhibits 1000-fold selectivity for GSK-3 over closely related kinases such as cdc2 |
| CSN13082 | Bikinin | 188011-69-0 | Bikinin acts as an ATP-competitive inhibitor of arabidopsis GSK-3 and effective activator of brassinosteroid BR signaling |
| CSN23598 | 5-Bromoindole | 10075-50-0 | 5-bromoindole is an inhibitor ofglycogen synthase kinase 3 GSK-3 it can be used as important pharmaceutical chemical intermediate |
| CSN18742 | 1-Azakenpaullone | 676596-65-9 | 1-Azakenpaullone is a potent and selective GSK-3 inhibitor with IC50 of 18 nM 100-fold selectivity over CDK1cyclin B and CDK5p25 |
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