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GSK-3
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN15707 | TWS119 | 601514-19-6 | TWS119 is inhibitor of glycogen synthase kinase-3 with IC50 of 30 nM |
| CSN16043 | Tideglusib | 865854-05-3 | Tideglusib is an irreversible GSK-3 inhibitor with IC50 of 5 nM and 60 nM for GSK-3WT (1 h preincubation) and GSK-3C199A (1 h preincubation), respectively. |
| CSN19500 | TDZD-8 | 327036-89-5 | TDZD-8, the derivative of thiadiazolidinone, is a selective inhibitor of GSK-3. It inhibits GSK-3 with IC50 of 2 M. |
| CSN16568 | SB-415286 | 264218-23-7 | SB-415286 is an ATP-competitive inhibitor of GSK3GSK3 with IC50 of 78 nM and Ki of 31 nM |
| CSN12268 | SB-216763 | 280744-09-4 | SB-216763 is potent and selective glycogen synthase kinase-3 GSK-3 inhibitor Ki 9 nM and competes with ATP |
| CSN18355 | LY2090314 | 603288-22-8 | LY2090314 is a potent inhibitor of glycogen synthase kinase-3 (GSK-3) with IC50s of 1.5 nM and 0.9 nM for GSK-3α and GSK-3β respectively. |
| CSN22886 | Lithium Carbonate | 554-13-2 | Lithium Carbonate inhibits GSK-3 in vivo. |
| CSN11250 | Kenpaullone | 142273-20-9 | Kenpaullone is an ATP-competitive inhibitor of CDK1cyclin B (IC50 0.4 M), CDK2cyclin A (IC50 0.68 M), CDK5p25 (IC50 0.85 M), lymphocyte kinase (IC50 0.47 M) , and GSK-3 (C50 0.23 M). |
| CSN11201 | Indirubin-3'-Monoxime | 160807-49-8 | Indirubin-3-monoxime is a powerful inhibitor of GSK-3 with IC50 of 22nM also inhibits CDK15 IC50 180100 nM |
| CSN17487 | IM-12 | 1129669-05-1 | IM-12 is a GSK-3 inhibitor with IC50 of 53 nM |
| CSN18354 | GSK-3 Inhibitor 1 | 603272-51-1 | GSK-3 inhibitor 1 is a potent GSK-3 inhibitor |
| CSN17624 | CP21R7 | 125314-13-8 | CP21R7 is a slective inhibitor of GSK-3 |
| CSN19149 | CHIR-99021 3HCl | 1782235-14-6 | CHIR-99021 trihydrochloride is a GSK-3 inhibitor with IC50 of 10 nM67 nM showing 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2 as well as other protein kinases |
| CSN13470 | CHIR-99021 | 252917-06-9 | CHIR-99021 is a GSK-3α/β inhibitor with IC50 of 10 nM/6.7 nM, exhibiting > 500-fold selectivity for GSK-3 versus its closest homologs CDC2 and ERK2, as well as other protein kinases. |
| CSN19176 | CHIR-99021 HCl | 1797989-42-4 | CHIR-99021 hydrochloride is hydrochloride of CHIR-99021 which is a GSK-3 inhibitor with IC50 of 10 nM67 nM and shows greater than 500-fold selectivity for GSK-3 versus its closest homologs Cdc2 and ERK2 |
| CSN20636 | CHIR-98024 | 556813-39-9 | CHIR-98014 is a reversible inhibitor of GSK3 and GSK3 with IC50 of 065 nM and 058 nM respectively |
| CSN23355 | CHIR-98014 | 252935-94-7 | CHIR-98014 CT98014 is highly selective aminopyrimidine-derivatived inhibitor of GSK-3 with IC50 of 650nM and 580nM for GSK-3 and GSK-3measured by kinase assays respectively and exhibits 1000-fold selectivity for GSK-3 over closely related kinases such as cdc2 |
| CSN16227 | BIO-Acetoxime | 667463-85-6 | BIO-acetoxime is an inhibitor of GSK3 and GSK3 with IC50 of 10 nM. |
| CSN16080 | BIO | 667463-62-9 | BIO is an inhibitor of GSK-3 and CDK1cyclinB complex. The IC50s of GSK-3, CDK1, CDK5 are 5 nM, 320 nM and 83 nM, respectively. |
| CSN13082 | Bikinin | 188011-69-0 | Bikinin acts as an ATP-competitive inhibitor of arabidopsis GSK-3 and effective activator of brassinosteroid BR signaling |
| CSN13894 | AZD2858 | 486424-20-8 | AZD2858 is an inhibitor of GSK-3 with IC50 of 68 nM that can inhibit the tau phosphorylation of S396 site and activate Wnt signaling pathway |
| CSN16226 | AZD1080 | 612487-72-6 | AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor of GSK3α and GSK3β with Ki of 6.9 nM and 31 nM, respectively, shows > 14-fold selectivity against CDK2, CDK5, CDK1 and Erk2. |
| CSN15984 | AR-A014418 | 487021-52-3 | AR-A014418 is a selective inhibitor of GSK3 with IC50 of 104 27 nM. |
| CSN23598 | 5-Bromoindole | 10075-50-0 | 5-bromoindole is an inhibitor ofglycogen synthase kinase 3 GSK-3 it can be used as important pharmaceutical chemical intermediate |
| CSN18742 | 1-Azakenpaullone | 676596-65-9 | 1-Azakenpaullone is a potent and selective GSK-3 inhibitor with IC50 of 18 nM 100-fold selectivity over CDK1cyclin B and CDK5p25 |
| CSN22657 | A 1070722 | 1384424-80-9 | |
| CSN22644 | 2B-(SP) | 186901-17-7 | |
| CSN23154 | TC-G 24 | 1257256-44-2 | |
| CSN23157 | TCS 2002 | 1005201-24-0 | |
| CSN23173 | TWS 119 | 1507095-58-0 |
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