Welcome to CSNpharm! For Research Use Only!
Glycine transporters (GlyTs) are plasmalemmal neurotransmitter transporters. They serve to terminate the signaling of glycine by mediating its reuptake from the synaptic cleft back into the presynaptic neurons. There are two glycine transporters: glycine transporter 1 (GlyT1) and glycine transporter 2 (GlyT2).
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN22250 | Tilapertin | 1000690-85-6 | Tilapertin is an oral inhibitor of glycine transporter type-1 GlyT1 |
| CSN15699 | Sarcosine | 107-97-1 | Sarcosine is an NMDAR co-agonist at the glycine binding site. It is an intermediate and byproduct in glycine synthesis and degradation. |
| CSN27664 | PF-03463275 | 1173239-39-8 | PF-03463275 is a centrally penetrant, orally available, selective, and competitive inhibitor of GlyT1 (glycine transporter-1) with Ki of 11.6 nM. |
| CSN19019 | LY2365109 hydrochloride | 1779796-27-8 | LY2365109 is a selective inhibitor of GlyT1 with IC50 of 158 nM |
| CSN22951 | LY 2365109 HCl | 868265-28-5 | LY 2365109 HCl is a potent and selective glycine transporter 1 (GlyT1) inhibitor with IC50 of 15.8 nM. |
| CSN18458 | Bitopertin (R enantiomer) | 845614-12-2 | Bitopertin R-enantiomer is a potent, noncompetitive glycine reuptake inhibitor, inhibits glycine uptake at human GlyT1 with a concentration exhibiting IC50 of 25 nM. |
| CSN13569 | Bitopertin | 845614-11-1 | Bitopertin is a noncompetitive inhibitor of glycine reuptake with IC50 of 25 nM. |
| CSN22690 | ASP2535 | 374886-51-8 | ASP 2535 is a potent and selective GlyT1 inhibitor with IC50 of 92 nM. |
+1-708-781-1677
+1-708-286-6026
sales@csnpharm.com
