G0S2 as a regulator of lipid metabolism. Promotes apoptosis by binding to BCL2, hence preventing the formation of protective BCL2-BAX heterodimers.
Cat. No. | Product Name | CAS No. | Information |
---|---|---|---|
CSN25657 | NS-3-008 hydrochloride | 1172854-54-4 | NS-3-008 is a novel transcriptional inhibitor of G0s2 with IC50 value of 2.25μM. It resulted in decreased levels of G0s2 and Ccl2 mRNA in the kidneys of wild-type 5/6Nx mice at dose of 5mg/kg. |