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FXR

FXR

Cat. No. Product Name CAS No. Information
CSN13148 Turofexorate isopropyl   629664-81-9 WAY-362450 is an agonist of farnesoid X receptor (FXR) with EC50 of 4 nM. WAY-362450 is used to the treatment of dyslipidemia.
CSN26168 Vonafexor 1192171-69-9 Vonafexor is a farnesoid X receptor agonist.
CSN23688 Tropifexor 1383816-29-2 Tropifexor is a potent agonist of FXR with EC50 of 026 nM
CSN15954 T0901317 293754-55-9 T0901317 is a selective agonist for LXR and FXR with EC50 of 50 nM and 5 M respectively
CSN26448 PX20606 trans racemate 1268244-85-4 PX20606, also known as PX-102, is a FXR agonist. PX20606 induces high-density lipoprotein-mediated transhepatic cholesterol efflux in mice and monkeys and prevent atherosclerosis in cholesteryl ester transfer protein transgenic low-density lipoprotein receptor (-/-) mice. PX20606 demonstrated potent plasma cholesterol-lowering activity that affected all lipoprotein species.
CSN21073 Nidufexor 1773489-72-7 Nidufexor is a potent farnesoid X receptor FXR agonist for the treatment of non-alcoholic steatohepatitis NASH and hepatobiliary disorders
CSN23776 LY2562175 1103500-20-4 LY2562175 is a selective and partial FXR agonist with EC50 of 193 nM
CSN11129 GW 4064 278779-30-9 GW4064 is a selective non-steroidal farnesoid X receptor FXR agonist EC50 15 nM
CSN15997 Fexaramine 574013-66-4 Fexaramine is a small molecule farnesoid X receptor FXR agonist with 100-fold increased affinity relative to natural compounds
CSN23903 Cilofexor 1418274-28-8 Cilofexor is a FXR agonist. 
CSN22796 DY268 1609564-75-1
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