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FXR

FXR

Cat. No. Product Name CAS No. Information
CSN13148 WAY-362450   629664-81-9 WAY-362450 is an agonist of farnesoid X receptor (FXR) with EC50 of 4 nM. WAY-362450 is used to the treatment of dyslipidemia.
CSN23688 Tropifexor 1383816-29-2 Tropifexor is a potent agonist of FXR with EC50 of 026 nM
CSN15954 T0901317 293754-55-9 T0901317 is a selective agonist for LXR and FXR with EC50 of 50 nM and 5 M respectively
CSN12883 Obeticholic Acid   459789-99-2 Obeticholic acid is a selective FXR agonist with EC50 of 99 nM and it has anticholestatic activity.
CSN21073 Nidufexor 1773489-72-7 Nidufexor is a potent farnesoid X receptor FXR agonist for the treatment of non-alcoholic steatohepatitis NASH and hepatobiliary disorders
CSN23776 LY2562175 1103500-20-4 LY2562175 is a selective and partial FXR agonist with EC50 of 193 nM
CSN17377 INT-767 1000403-03-1 INT-767 is a potent agonist for both FXR mean EC50 30 nM by PerkinElmer AlphaScreen assay and TGR5 mean EC50 630 nM by time resolved-fluorescence resonance energy transfer
CSN11129 GW4064 278779-30-9 GW4064 is a selective non-steroidal farnesoid X receptor FXR agonist EC50 15 nM
CSN15997 Fexaramine 574013-66-4 Fexaramine is a small molecule farnesoid X receptor FXR agonist with 100-fold increased affinity relative to natural compounds
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