1.Each sample can be applied for only once. Customers are limited to three different samples in 180 days.
2.Customers in USA are responsible for $35 shipping & handling fee. For other countries, please contact us to get quotation.
3.We will ask for your feedback about our products and service.
4.Our products are for research use only!
Cat. No. | Product Name | CAS No. | Information |
---|---|---|---|
CSN12515 | Losartan Potassium | 124750-99-8 | Losartan Potassium is the potassium salt form of Losartan, which is a compeitive AT1 receptor inhibitor with IC50 value of 20 nM. |
CSN13680 | ABT-199 | 1257044-40-8 | ABT-199 is a highly potent inhibitor of Bcl-2, re-engineered from ABT-263. It has subnanomolar affinity (Ki<0.010 nM, analysis by TR–FRET assay), which is over three orders of magnitude to Bcl-XL (Ki=48nM) and Bcl-W (Ki=245 nM). |
CSN16807 | Imatinib Mesylate | 220127-57-1 | Imatinib Mesylate is the mesylate form of Imatinib. Imatinib is a multiple target inhibitor with IC50 values of 100nM, 100nM, 38nM, 25nM and 25nM for PDGFR, c-kit, v-Abl, c-abl and bcr-abl, respectively, usually used for treatment of chronic myelogenous leukemia. |
CSN13702 | Salicin | 138-52-3 | Salicin is a non-selective COX-1 and COX-2 inhibitor, it is a phenol β-glycosid isolated and purified from the peel of Salix alba L.and shows anti-inflammatory effects. |
CSN11280 | Lenalidomide | 191732-72-6 | Lenalidomide, a thalidomide analog, is a TNF-α secretion inhibitor with IC50 of 13 nM. |
CSN12073 | Thalidomide | 50-35-1 | Thalidomide interacts directly with the protein cereblon (CRBN; IC50 = 8.5 nM), a ubiquitously-expressed E3 ligase. And binding of thalidomide analogs to CRBN-DNA damage binding protein-1 complexes (CRBN-DDB1-Cul4A complex) account for the immunomodulatory and antiproliferative effects of these compounds. |
CSN13185 | Pomalidomide | 19171-19-8 | Pomalidomide inhibits lipopolysaccharide (LPS) stimulated TNF-alpha release in human PBMC and in human whole blood with IC50 values of 13 nM and 25 nM, respectively. Pomalidomide inhibits the growth of T regulatory cells which is stimulated by IL-2 with an IC50 of ~1 μM. Treatment with Pomalidomide (6.4 nM-10 μM) increases the production of IL-2 in human peripheral blood T cells, and is slightly more potent in the CD4+ subset than in the CD8+ subset. Pomalidomide is significantly more potent than CC-5013 at elevating IL-2, IL-5, and IL-10 levels, but only slightly more potent than CC-5013 at elevating IFN-γ levels. Pomalidomide enhances SEE and Raji cells induced AP-1 transcriptional activity in Jurkat cells in a dose-dependent manner, with a maximal enhancement of 4-fold at 1 μM. Exposure of Raji cells to various concentrations of Pomalidomide (2.5-40 μg/mL) for 48 hours leads to a significant decrease in cell proliferation and DNA synthesis. There is a reduction of ~40% compared to vehicle-treated controls. |
CSN16132 | Mycophenolate mofetil | 128794-94-5 | Mycophenolate mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II with IC50 of 39 nM and 27 nM, respectively. |
CSN12842 | Dopamine HCl | 62-31-7 | Dopamine hydrochloride works as a catecholamine neurotransmitter and a dopamine receptors agonist. It can treat various types of shock clinically. |
CSN10805 | Diethylstilbestrol | 56-53-1 | Diethylstilbestrol is a synthetic nonsteroidal estrogen that produces all the pharmacological and therapeutic effects of natural estradiol. It is mainly used for functional hemorrhage caused by estrogen hypoxia and hormonal imbalance, amenorrhea. |
CSN17329 | Daidzein | 486-66-8 | Daidzein can act as an inhibitor of tyrosine kinase and an activator of estrogen receptor. It is inactive analogue of genistein. |
CSN17077 | Y15 | 4506-66-5 | Y15 is a selective FAK inhibitor. |
CSN12374 | Tripelennamine HCl | 154-69-8 | Tripelennamine hydrochloride, a H1-receptor antagonist, is a psychoactive drug and member of the pyridine andethylenediamine classes that is used as an antipruritic and first-generation antihistamine. |
CSN13892 | Epacadostat | 1204669-58-8 | Epacadostat is a selective IDO1 inhibitor with IC50 value of ~10nM with little activity against the related enzymes IDO2 or TDO. |
CSN16720 | Fingolimod HCl | 162359-56-0 | Dinotefuran is the third generation of neonicotinoid group,which works through inhibiting nAchRs. |
CSN19486 | Paclitaxel | 33069-62-4 | Paclitaxel can stabilize the microtubule formation through interacting with β-tubulin and then promoting the polymerization and assembly of it. |
CSN10001 | Levofloxacin | 100986-85-4 | Adenosine is a nucleoside that is composed of adenine and d-ribose and plays many important biological roles in addition to being components of DNA and RNA. |
CSN16581 | Campathecin | 7689-03-4 | Camptothecin is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231. |
CSN16761 | Sunitinib | 557795-19-4 | Sunitinib is a multiple RTKs inhibitor with IC50 values of 2nM and 80nM for VEGFR2 and PDGFRβ, respectively, also shows inhibition against KIT and FLT3 receptor. |
CSN19418 | Retinoic acid | 302-79-4 | Oridonin, a diterpenoid purified from Rabdosia rubescens, is an antitumor agent. |
CSN11410 | Methyl Gallate | 99-24-1 | Methyl gallate, a natural product isolated and purified from the herbs of Sapium sebiferum, is a reverse transcriptase inhibitor. |
CSN10424 | Caffeic Acid | 331-39-5 | Caffeic acid is a hydroxycinnamic acid, a naturally occurring organic compound isolated and purified from the herb of Boehmeria siamensis Craib., with antioxidant, antineoplastic, anti-HIV, choleretic, hepatotropic, and is a strong inhibitor of neutrophil elastase. |
CSN11247 | Kanamycin Sulfate | 25389-94-0 | Kanamycin Sulfate is an antibiotic complex produced by Streptomyces kanamyceticus from Japanese soil and is effective as a bacteriocidal agent by inhibiting ribosomal translocation and eliciting miscoding. It is usually used in cloning selection. |
CSN15946 | Doxycycline Hyclate | 24390-14-5 | Doxycycline Hyclate is a broad-spectrum antibiotic used to treat infections caused by bacteria, including pneumonia and other respiratory tract infections, and an MMP inhibitor. |
CSN16742 | Carbenicillin Disodium | 4800-94-6 | Carbenicillin Disodium is a broad-spectrum, semi-synthetic penicillin antibiotic. |
CSN12629 | Coenzyme Q10 | 303-98-0 | Coenzyme Q10 is a component of the electron transport chain and participates in aerobic cellular respiration. |
CSN10452 | Biotin NHS | 35013-72-0 | Biotin NHS is a membrane-permeable compound for labeling intracellular proteins by forming irreversible amide bonds. |