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The FMS-like tyrosine kinase-3 internal tandem duplication (FLT3-ITD) is one of the most frequent mutations found in acute myeloid leukemia (AML) patients, with a frequency of 20–30%.
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN28461 | PROTAC FLT-3 degrader 1 | 2230826-81-8 | PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 internal tandem duplication (ITD) degrader with an IC50 0.6 nM. Anti-proliferative activity; apoptosis induction. |
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