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Flavonoids

Flavonoids

Cat. No. Product Name CAS No. Information
CSN16440 Wogonin   632-85-9 Wogonin acts as an inhibitor of COX2 with IC50 of 46 M without affecting COX-1 and inhibits the NF-B pathway-mediated iNOs induction. Wogonin can be isolated from the root of scutellaria baicalensis georgi.
CSN19930 Vitexin-4″-O-Glucoside   76135-82-5 Vitexin-4-O-Glucoside can inhibit TPO activity. It is a natural product isolated and purified from the fruit of Crataegus pinnatifida Bge.
CSN14606 Thevetiaflavone 29376-68-9 Thevetiaflavone is a natural product isolated and purified from the herbs of Wikstroemia indica.
CSN12074 Theaflavin   4670-05-7 Theaflavin, a type of thearubigins, exhibits inhibition of xanthine oxidase enzyme and can scavenge various oxidation radicals with anti-oxidant and anti-tumor activities. It can be purified from the leaves of Camellia sinensis (L.) O. Kuntze.
CSN14278 Tetrahydroamentoflavone 48236-96-0 Tetrahydroamentoflavone, a potent XO inhibitor isolated and purified from the herbs of Selaginella uncinata, exerts its antioxidant activity in vitro through metal-chelating, and radical-scavenging, and has anti-inflammatory effects. It shows in vitro cyclooxygenase (COX) inhibition activity ( an IC(50) value of 29.5 microM (COX-1) and 40.5 inhibition at 100 mgmL (COX-2)).
CSN10060 Tectochrysin 520-28-5 Tectochrysin, a natural product isolated and purified from the heartwood of Pinus strobus L., leads to apoptotic cell death in NSCLC cells through activation of DR3 and Fas expression via inhibition of STAT3 phosphorylation.
CSN14314 Sideritoflavone 70360-12-2 Sideritoflavone is a natural product isolated and purified from the aerial parts of Stachys glutinosa. with anti-inflammatory effect , and is a selective inhibitor of lipoxygenase activity in vitro.
CSN10165 Scutellarin   27740-01-8 Scutellarin is an active flavonoid that shows anti-tumor activity and anti-proteasome action. It can be isolated from the root of Scutellaria baicalensis Georgi.
CSN12572 Rhoifolin 17306-46-6 Rhoifolin, a natural product isolated and purified from the leaves of Turpinia arguya Seem, hows monolithic proliferation inhibitory activities against Hela, A549 and MCF-7 cell lines, and may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor- and GLUT4.
CSN11617 Oroxylin A   480-11-5 Oroxylin A shows inhibition of the dopamine reuptake and allosteric modulation of GABAA receptor. It is a natural active flavonoid isolated from scutellaria baicalensis and oroxylum indicum.
CSN13300 Naringenin Triacetate 3682-04-0 Naringenin triacetate is a natural product isolated and purified from the fruits of Citrus aurantium L. with a better binding affinity with multiple crystal structures of first bromodomain BRD4 (BRD4 BD1) when compared with the known inhibitors.
CSN15664 Morusin 62596-29-6 Morusin shows suppression of NFB and STAT3 in many cancer cell lines including HT-29, A549, MCF-7, and MDA-MB-231. It is a flavonoid purified from the root bark of morus alba L. with antitumor activity.
CSN15566 Mirabijalone D 485811-84-5 Mirabijalone D, a natural product isolated and purified from Abronia nana, is a non-competitive inhibitor based on the Dixon plot, and inhibits A142 production by 43.7 in APPSW-N2a cells.
CSN22079 Quercetin-3-O-glucuronide 22688-79-5 Miquelianinis a metabolite of quercetin and a type of natural flavonoid which blocks β2-adrenergic signaling.
CSN12274 Liquiritigenin 578-86-9 Liquiritigenin is an estrogenic compound which fuctions as a selective agonist of the estrogen receptor ER and an partial agonist of ER. It also has choleretic effect. Liquiritigenin is a flavanone extracted from glycyrrhiza uralensis with antitumour action.
CSN15416 Leachianone G 152464-78-3 Leachianone G, a natural product isolated and purified from the roots of Sophora flavescens Ait., shows inhibitory activities against pancreatic lipase, and may be used as drug candidate to control obesity. Leachianone G exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays, and shows potent antiviral activity (IC(50) 1.6 mgmL).
CSN15422 Kushenol X 254886-77-6 Kushenol X is a natural product isolated and purified from the roots of Sophora flavescens Ait. exhibiting inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).
CSN14297 Kushenol A 99217-63-7 Kushenol A, a kind of Adenosine 3, 5-cyclic monophosphate(cAMP)phosphodiesterase inhibitiors isolated and purified from the roots of Sophora flavescens Ait., exhibits inhibitory activity against sodium-dependent glucose cotransporter 2(SGLT2 and shows selective alpha-glucosidase inhibitory activity.
CSN11241 Kaempferitrin   482-38-2 Kaempferitrin can activate insulin signaling pathway, phosphorylate Akt kinase and exert the transloocation of GLUT4, thus has antitumor, antidepressant and antidiabetic effects. Kaempferitrin is a natural product isolated and purified from the root of Kaempferia galangal L..
CSN13127 Jaceosidin   18085-97-7 Jaceosidin, a methylated trihydroxyflavone, can induce apoptosis in cancer cells via activating Bax and also could block signaling pathways related to inflammation. It is first isolated from the Compositae family.
CSN13968 Isovitexin 38953-85-4 Isovitexin, a natural product isolated and purified from the seeds of Vitex trifolia L., exhibits a potential antioxidant activity, shows a strong antihyperglycemic action, and inhibits -glucosidase in vivo.
CSN12677 Isorhamnetin 480-19-3 Isorhamnetin, a natural flavonol aglycone, can inhibit xanthine oxidase with IC50 of 400nM and stabilize -catenin as well as up-regulate the Wnt signaling pathway. Isorhamnetin could also be act as an apoptosia inducer with antitumor activities.
CSN11174 Isoquercitrin   482-35-9 Isoquercitrinis can inhibit Wnt-catenin and activate the mitogen-activated protein kinase (MAPK) signalling pathway. It is a natural product isolated and purified from the herbs of Prunella vulgaris L. with a good effect of expectorant, cough, asthma and anti-tumoral activity.
CSN19903 Isoorientin 4261-42-1 Isoorientin is a natural product isolated and purified from the herbs of Polygonum orientale Linn. with antioxidant activity.
CSN16383 Hesperetin   520-33-2 Hesperetin is a flavanone extracted from the peel of citrus that exhibits inhibition of PDE4 and UGT. Hesperetin has antioxidative and anti-inflammatory effects as well.
CSN13969 Guaijaverin 22255-13-6 Guaijaverin, a natural product isolated and purified from the fruits of Psidium guajava Linn., has antioxidant activity and antibacterial activity against Strep. mutans.
CSN11100 Glabridin   59870-68-7 Glabridin has many biological functions such as regulating the synthesis and activity of iNOS under high-glucose levels, significantly inhibiting free radicals generated during metabolism in the body, and protecting against oxidation-sensitive biomacromolecules (LDL, LDL, DNA) and cell walls. It is a natural product isolated and purified from the roots of Glycyrrhiza glabra L. with whitening and anti-aging activity.
CSN13970 Engeletin 572-31-6 Engeletin, a natural product isolated and purified from the leaves of Engelhardtia roxburghiana Wall., may serve as a potential anti-inflammatory agent. Engeletin possesses potent inhibition of PGE2 release with IC50 values of 19.6 gmL.
CSN14824 Derrone 76166-59-1 Derrone, a natural product isolated and purified from the herbs of Cudrania tricuspidata, may be interesting antimicrobial agents to be used against infectious diseases caused by many pathogens, and is an Aurora kinase inhibitor, it can significantly inhibit the formation and growth of MCF7 tumor spheroids.
CSN15420 Corylifol C 775351-91-2 Corylifol C is a natural product isolated and purified from the seeds of Psoralea corylifolia L., and a potent protein kinase inhibitors (inhibitory concentration 50 values for epidermal growth factor receptor (EGFR) 1.1 and 4.4 10(-6) gmL, respectively).
CSN10135 Cirsiliol 34334-69-5 Cirsiliol, a natural product, induces radiosensitization and inhibition of epithelial-mesenchymal transition (EMT) by miR-34a-mediated suppression of Notch-1 expression in non-small cell lung cancer cell lines.
CSN14022 Chrysosplenetin 603-56-5 Chrysosplenetin, a natural product isolated and purified from the herbs of Laggera pterodonta, is a metabolic inhibitor of artemisinin.
CSN12352 Calycosin   20575-57-9 Calycosin, a phytoestrogen, is a partial agonist of ER and a calcium channel blocker. It also shows prevention of reperfusion injury. Calycosin can be isolated and purified from the herb of Astragalus membranaceus Bge. var. mongholicus with anti-oxidative activity.
CSN15665 Baohuoside I 113558-15-9 Baohuoside I, a flavonoid, acts as an apoptosis inducer and a down-regulator of durvivin and cyclin D1 expression. It is used as an anti-cancer agent and can be isolated and purified from the roots of epimedium brevicornu Maxim.
CSN16193 Baicalin 21967-41-9 Baicalin, the glucuronide of baicalein, exhibits the reduction of the expression of NF-B and effect on GABA receptor. Baicalin can be extracted from the root of astragalus membranaceus with antioxidant and anti-inflammatory activities.
CSN12275 Aromadendrin 480-20-6 Aromadendrin, a natural product isolated and purified from the bark of Eucalyptus calophylla, has anti-diabetic, anti-inflammatory, and antioxidant effects.
CSN19966 Apiin   26544-34-3 Apiin can inhibit iNOS expression and nitrite production in J774.A1 cells. It is a flavonoid isolated from the herbs of petroselinum crispum.
CSN12350 Acacetin   480-44-4 Acacetin shows inhibiton of the proliferation and induction apoptosis for cancer cells. It is a flavonoid purified from the bark of acacia farnesiana with anti-peroxidant, antiarthritic, and anti-inflammatory activities,
CSN19459 7,4'-Di-O-methylapigenin   5128-44-9 7,4-Di-O-methylapigenin, a flavonoid purified from aquilaria sinensis, can inhibit -glucosidase, -amylase enzymes and enhance 2-NBDG uptake in L6 cells. It has hypolipidemic effect.
CSN13014 7,3',4'-Trihydroxy-3-Benzyl-2H-Chromene 1111897-60-9 7,3,4-Trihydroxy-3-benzyl-2H-chromene, a natural product isolated and purified from the heartwoods of Caesalpinia sappan L., is a potential xanthine oxidase inhibitor.
CSN10156 6-Methoxyluteolin 520-11-6 6-Methoxyluteolin is a natural product isolated and purified from the flower of Chrysanthemum zawadskii var. latilobum with antioxidant activity and is also a potent inhibitor of histamine release and calcium influx via down-regulation of the FcRI chain.
CSN16835 (-)-Epigallocatechin   970-74-1 (-)-Epigallocatechin is a plant secondary metabolite abundant in green tea, it can prevent conversion of unfolded native polypeptides to amyloid fibrils.
CSN11587 (-)-Epicatechin Gallate 1257-08-5 (-)-Epicatechin gallate, a polyphenol, is a apoptosis inducer of tumor cells that found in green tea.
CSN16833 (-)-Catechin Gallate 130405-40-2 (-)-Catechin gallate is a natural product isolated and purified from the wood of Acacia catechu (L.F.) Willd., can enhance Fe(2)-induced lipid peroxidation.
CSN16512 (+)-Catechin   154-23-4 (+)-Catechin, a plant secondary metabolite, is an antioxidant flavonoid found in the bark of taxus yunnanensis with anti-atherosclerosis.
CSN14847 Licoflavonol 60197-60-6
CSN14614 Glabrene 60008-03-9
CSN14055 Velutin 25739-41-7
CSN14309 Juglanin 5041-67-8
CSN19988 Herbacetin 527-95-7
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