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Factor Xa

Factor Xa

Cat. No. Product Name CAS No. Information
CSN12263 Rivaroxaban 366789-02-8 Rivaroxaban is an inhibitor of factor Xa FXa with IC50 of 07 nM and Ki of 04 nM which developed for the treatment of thrombotic disease
CSN26500 Razaxaban hydrochloride 405940-76-3 Razaxaban, also known as BMS-561389; BMS-561389-01; DPC-906; BMS-561389-06, is a factor Xa inhibitor potentially for the treatment of thrombosis. Razaxaban was an effective antithrombotic agent in a rabbit model of arterial thrombosis. Low-dose razaxaban was useful in combination with sub-optimal doses of aspirin and/or clopidogrel for the prevention of occlusive arterial thrombosis without excessive bleeding.
CSN18070 Otamixaban 193153-04-7 Otamixaban is a potent Ki 05 nM selective rapid acting competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa
CSN12447 Fondaparinux sodium   114870-03-0 Fondaparinux sodium is a pentasaccharide inhibitor of antithrombin-dependent factor Xa (IC50 40 nM). It can bind to antithrombin III.
CSN15688 Edoxaban tosylate monohydrate   1229194-11-9 Edoxaban tosylate is a selective factor Xa inhibitor with Ki of 0561 nM 10 000-fold selectivity over thrombin and FIXa and is also an orally bioavailable anticoagulant drug
CSN12900 Edoxaban   480449-70-5 Edoxaban is an oral factor Xa FXa inhibitor in clinical development for stroke prevention
CSN13691 Edoxaban tosylate 480449-71-6 Edoxaban is an oral factor Xa FXa inhibitor in clinical development for stroke prevention
CSN28842 Darexaban 365462-23-3 Darexaban is a potent and orally effective factor Xa inhibitor with IC50 value of 54.6nM.
CSN12369 Betrixaban 330942-05-7 Betrixaban is a highly potent selective and orally efficacious factor Xa inhibitor with IC50 of 12 nM inhibition of Factor 10a
CSN12320 Apixaban   503612-47-3 Apixaban is a direct factor Xa inhibitor with an IC50 of 008 nM and 017 nM in human and rabbit respectively
CSN18499 5-R-Rivaroxaban 865479-71-6 5-R-Rivaroxaban is an R enantiomer of rivaroxaban an oral direct Factor Xa FXa inhibitor in late-stage development for the prevention and treatment of thromboembolic disorders
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