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Factor Xa
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN12263 | Rivaroxaban | 366789-02-8 | Rivaroxaban is an inhibitor of factor Xa FXa with IC50 of 07 nM and Ki of 04 nM which developed for the treatment of thrombotic disease |
| CSN26500 | Razaxaban HCl | 405940-76-3 | Razaxaban, also known as BMS-561389; BMS-561389-01; DPC-906; BMS-561389-06, is a factor Xa inhibitor potentially for the treatment of thrombosis. Razaxaban was an effective antithrombotic agent in a rabbit model of arterial thrombosis. Low-dose razaxaban was useful in combination with sub-optimal doses of aspirin and/or clopidogrel for the prevention of occlusive arterial thrombosis without excessive bleeding. |
| CSN18070 | Otamixaban | 193153-04-7 | Otamixaban is a potent Ki 05 nM selective rapid acting competitive and reversible fXa inhibitor that effectively inhibits both free and prothrombinase-bound fXa |
| CSN12447 | Fondaparinux Sodium | 114870-03-0 | Fondaparinux sodium is a pentasaccharide inhibitor of antithrombin-dependent factor Xa (IC50 40 nM). It can bind to antithrombin III. |
| CSN15688 | Edoxaban Tosylate Monohydrate | 1229194-11-9 | Edoxaban tosylate is a selective factor Xa inhibitor with Ki of 0561 nM 10 000-fold selectivity over thrombin and FIXa and is also an orally bioavailable anticoagulant drug |
| CSN12900 | Edoxaban | 480449-70-5 | Edoxaban is an oral factor Xa FXa inhibitor in clinical development for stroke prevention |
| CSN28842 | Darexaban | 365462-23-3 | Darexaban is a potent and orally effective factor Xa inhibitor with IC50 value of 54.6nM. |
| CSN12369 | Betrixaban | 330942-05-7 | Betrixaban is a highly potent selective and orally efficacious factor Xa inhibitor with IC50 of 12 nM inhibition of Factor 10a |
| CSN12320 | Apixaban | 503612-47-3 | Apixaban is a direct factor Xa inhibitor with an IC50 of 008 nM and 017 nM in human and rabbit respectively |
| CSN18499 | 5-R-Rivaroxaban | 865479-71-6 | 5-R-Rivaroxaban is an R enantiomer of rivaroxaban an oral direct Factor Xa FXa inhibitor in late-stage development for the prevention and treatment of thromboembolic disorders |
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