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ERR

Cat. No. Product Name CAS No. Information
CSN16637 Tectoridin   611-40-5 Tectoridin, an isoflavone, is a natural product isolated and purified from the rhizomes of belamcanda chinensis (L.) DC. with anti-inflammatory activities.
CSN11817 Quinestrol   152-43-2 Quinestrol is a synthetic estrogen which is used in hormone replacement therapy.
CSN19099 MGL-3196 920509-32-6 MGL-3196 is a selective thyroid hormone receptor agonist with EC50s of 0.21 and 3.74 M for TR and TR respectively.
CSN12271 L-Thyroxine   51-48-9 L-Thyroxine is an iodine-containing hormone produced from thyroglobulin in the thyroid follicular cells.
CSN22842 GSK 4716 101574-65-6 GSK4716 is an agonist of ERR with IC50 of 2 M with similar potency as the protein ligand PGC-1
CSN19421 Genistin   529-59-9 Genistin is a isoflavone which has a role in blocking cell cycle and inducing apoptosis. It is also a modulator of estrogen receptor. Genistin can be isolated from the seeds of glycine max (L.) merr. and used as negative control of genistein.
CSN10938 Estropipate   7280-37-7 Estropipate, deriving from estrogen, is used to treat symptoms of menopause and to prevent osteoporosis.
CSN25302 Estrogen receptor modulator 1 63676-22-2 Estrogen receptor modulator 1 is an orally active and selective estrogen receptor modulator (SERM), with a pIC50 of 0.46. It has been found to be both estrogenic and antiproliferative in ER-positive endocrine-resistant breast cancer cell lines that overexpress protein kinase C alpha (PKCα).
CSN10935 Estradiol Benzoate   50-50-0 Estradiol benzoate is an estradiol analog which binds to the human, murine and chicken ER with IC50 of 22-28 nM.
CSN27511 ERRα antagonist-1 1072145-33-5 ERRα antagonist-1 (Compound A) is a selective and high affinity estrogen-related receptor α (ERRα) antagonist. ERRα antagonist-1 inhibits interaction of ERRα with Proliferator-activated Receptor γ Coactivator-1α (PGC-1α) and PGC-1β, the IC50 values are 170 nM and 180 nM, respectively. ERRα antagonist-1 does not inhibit the interaction of either ERRβ or ERRγ with PGC-1α and PGC-1β coactivator, and also does not inhibit interaction of ERα or ERβ with PGC-1α or SRC-1.
CSN10623 Chlorotrianisene   569-57-3 Chlorotrianisene, a synthetic and non-steroidal estrogen, is a modulator of estrogen receptor.
CSN22105 4-Hydroxytamoxifen 68047-06-3 4-Hydroxytamoxifen is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer.
CSN17211 α-Estradiol 57-91-0 -Estradiol is an endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ER and ER receptors respectively).
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