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Cat. No. Product Name CAS No. Information
CSN16334 XCT790 725247-18-7 XCT-790 is an agonist of estrogen related receptor alpha ERR and can induce death of cancer cells resistant to chemotherapy
CSN20458 WAY200070 440122-66-7 WAY200070 selectively activates ER EC50 2 nM receptor over ER EC50 155 nM It shows anti-depressive and anti-anxiolytic activities
CSN17140 Ulipristal   159811-51-5 Ulipristal is a selective progesterone receptor modulator SPRM for inhibiting or delaying ovulation
CSN19977 Tracheloside 33464-71-0 Tracheloside a natural product isolated and purified from the herbs of Trachelospermum jasminoides Lindl Lem significantly decreases the activity of alkaline phosphatase AP an estrogen-inducible marker enzyme with an IC50 value of 031 mgmL a level of inhibition comparable to that of tamoxifen IC50 043 mgmL
CSN22522 TR Antagonist 1 500794-88-7 TR antagonist 1 is a high-affinity thyroid hormone receptor TR antagonist with IC50s of 36 and 22 nM for TR and TR respectively
CSN21231 Tetrahydrofluoroene 52 1398510-92-3 Tetrahydrofluoroene 52 is a potent and selective estrogen receptor agonist
CSN11752 Tesmilifene 98774-23-3 Tesmilifene is an agent that augments cytotoxicity of various chemotherapeutic agents both in vitro and in vivo
CSN16637 Tectoridin   611-40-5 Tectoridin, an isoflavone, is a natural product isolated and purified from the rhizomes of belamcanda chinensis (L.) DC. with anti-inflammatory activities.
CSN22304 SNIPER(ER)-110 N/A SNIPERER-110 is a nongenetic IAP-dependent protein eraser SNIPER targeting estrogen receptor ER induces ER degradation and induces apoptosis in MCF-7 human breast cancer cells inhibits the growth of MCF-7 tumor xenografts in mice more potently than the previously characterized SNIPERER-87 preferentially recruits XIAP rather than cIAP1 to degrade ER
CSN21407 MPP 2HCl 911295-24-4 Selective high affinity silent antagonist at ER receptors Displays 200-fold selectivity for ER over ER Ki values are 27 and 1800 nM at ER and ER receptors respectively
CSN11817 Quinestrol   152-43-2 Quinestrol is a synthetic estrogen which is used in hormone replacement therapy.
CSN22305 PAC1 2158322-33-7 PAC1 Compound PAC1 is a PROTAC antibody conjugate more potent estrogen receptor-alpha ER degrader compared to PROTAC without antibody conjugation
CSN15897 Ospemifene   128607-22-7 Ospemifene is a non-hormonal estrogen receptor modulator SERM with IC50 values of 827 nM and 1633 nM for ER and ER Ospemifene is one of the active metabolites of toremifene
CSN20291 Ormeloxifene 31477-60-8 Ormeloxifene an estrogen receptor regulator suppresses prostate tumor growth and metastatic phenotypes via inhibition of oncogenic -catenin signaling and EMT progression
CSN21337 Nitromifene 10448-84-7 Nitromifene is an antagonist of estrogen receptor ER
CSN13823 Nafoxidine HCl 1847-63-8 Nafoxidine hydrochloride is a non-steroidal selective estrogen receptor modulator SERM or partial antiestrogen of the triphenylethylene group that was developed for the treatment of advanced breast cancer
CSN11387 Mestranol 72-33-3 Mestranol is an agonist of estrogen receptor. It is used as contraceptives.
CSN21092 LSZ102 2135600-76-7 LSZ102 is a potent ER antagonist and degrader LSZ102 showed ER degradation IC50 02 nM LSZ102 demonstrated IC50 for MCF-7 cells 17 nM Upon administration of LSZ102 this agent binds to the ER and induces the degradation of the receptor This prevents ER activation and ER-mediated signaling and inhibits the growth and survival of ER-expressing cancer cells
CSN16424 Licochalcone A 58749-22-7 Licochalcone A an estrogenic flavanoid can be an inhibitor of p-glycoprotein and has anti-inflammatory actions
CSN16955 Lasofoxifene Tartrate 190791-29-8 Lasofoxifene tartrate a non-steroidal compound is a modulator of estrogen receptor
CSN16382 Kaempferol 520-18-3 Kaempferol acts as an inverse agonist that directly binds ERR and ERR It is a natural flavonol with antitumor activity
CSN11148 Hexestrol 84-16-2 Hexestrol can bind to ER and ER selectively with EC50 of 007 nM and 0175 nM respectively
CSN22408 GC 14 447415-34-1 GC 14 is a selective agonist of thyroid hormone 1 activation TR1 with an EC50 of 680 nM
CSN10946 Ethisterone   434-03-7 Ethisterone is a progestogen hormone that could be used to treat prostate cancer.
CSN10938 Piperazine Estronesulfate   7280-37-7 Estropipate, deriving from estrogen, is used to treat symptoms of menopause and to prevent osteoporosis.
CSN10936 Estradiol Valeate   979-32-8 Estradiol valerate is a synthetic estrogen Formulations containing estradiol valerate with other steroid hormones have been used to treat endometriosis
CSN10935 Estradiol Benzoate   50-50-0 Estradiol benzoate is an estradiol analog which binds to the human, murine and chicken ER with IC50 of 22-28 nM.
CSN22143 ERB-196 550997-55-2 ERB-196 is a nonsteroidal selective estrogen receptor- (ER) agonist.
CSN12284 Equol   531-95-3 Equol, a non-steroidal estrogen, is a selective agonist of ER. It is produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora.
CSN10926 Equilin 474-86-2 Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine
CSN17408 Endoxifen Z-Isomer HCl 1032008-74-4 Endoxifen Z-isomer hydrochloride is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha ER Endoxifen Z-isomer hydrochloride inhibits hERG tail currents at 50 mV in a concentration-dependent manner with IC50 values of 16 M
CSN17474 Endoxifen Z-Isomer 112093-28-4 Endoxifen is the most important tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha ER
CSN17545 Endoxifen E-isomer HCl 1197194-61-8 Endoxifen E-isomer hydrochloride is a tamoxifen metabolite and potent Selective Estrogen Response Modifier SERM
CSN19762 Elacestrant 722533-56-4 Elacestrant is an orally available selective estrogen receptor degrader SERD and selective estrogen receptor modulator SERM with potential antineoplastic and estrogen-like activities
CSN19763 Elacestrant 2HCl 1349723-93-8 Elacestrant dihydrochloride is an orally available selective estrogen receptor degrader SERD and selective estrogen receptor modulator SERM with potential antineoplastic and estrogen-like activities
CSN15920 DPN 1428-67-7 DPN is a non-steroidal estrogen receptor ER selective ligand
CSN10805 Diethylstilbestrol   56-53-1 Diethylstilbestrol is a synthetic nonsteroidal estrogen that produces all the pharmacological and therapeutic effects of natural estradiol It is mainly used for functional hemorrhage caused by estrogen hypoxia and hormonal imbalance amenorrhea
CSN17329 Daidzein   486-66-8 Daidzein can act as an inhibitor of tyrosine kinase and an activator of estrogen receptor It is inactive analogue of genistein
CSN10623 Chlorotrianisene   569-57-3 Chlorotrianisene, a synthetic and non-steroidal estrogen, is a modulator of estrogen receptor.
CSN12297 Bazedoxifene 198481-32-2 Bazedoxifene is a selective estrogen receptor modulator SERM currently in development for osteoporosis prevention and treatment
CSN10382 Bazedoxifene Acetate 198481-33-3 Bazedoxifene acetate can selectively modulate estrogen receptor (SERM), the IC50 values are 26 nM and 99 nM for ER and ER respectively.
CSN17980 AZD9496 1639042-08-2 AZD9496 is a selective antagonist of estrogen receptor Er IC50 028 nM
CSN22351 Arzoxifene HCl 182133-27-3 Arzoxifene hydrocloride is a selective estrogen receptor modulator that is a potent estrogen antagonist in mammary and uterine tissue while acting as an estrogen agonist to maintain bone density and lower serum cholesterol.
CSN22335 Acolbifene 182167-02-8 Acolbifene (EM652) is a fourth-generation selective estrogen receptor antagonist with a LC50 value of 223 nM.
CSN22105 4-Hydroxytamoxifen 68047-06-3 4-Hydroxytamoxifen is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer.
CSN17213 17-Caproxyprogesterone   630-56-8 17-Caproxyprogesterone is a steroidal progestin. It is a synthetic ester derivative of 17-hydroxyprogesterone.
CSN17211 α-Estradiol 57-91-0 -Estradiol is an endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ER and ER receptors respectively).
CSN10426 β-Estradiol 17-acetate 1743-60-8 -Estradiol 17-acetate is a metabolite of estradiol.
CSN21091 GDC-0927 1642297-01-5
CSN22102 4,4-DDE 72-55-9
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