The ErbB protein family or epidermal growth factor receptor (EGFR) family is a family of four structurally related receptor tyrosine kinases. Insufficient ErbB signaling in humans is associated with the development of neurodegenerative diseases, such as multiple sclerosis and Alzheimer's Disease. The ErbB protein family consists of 4 members: ErbB-1, also named epidermal growth factor receptor (EGFR); ErbB-2, also named HER2 in humans and neu in rodents; ErbB-3, also named HER3; ErbB-4, also named HER4.
|Cat. No.||Product Name||CAS No.||Information|
|CSN25738||AG 825||149092-50-2||AG 825 is a selective inhibitor of ErbB2 and the IC50 values are 0.15 and 19 μM for ErbB2 and ErbB1 respectively.|