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Elastase
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN22536 | ZD-0892 | 171964-73-1 | ZD-0892 is a selective and potent inhibitor of a neutrophil elastase with Kis of 67 and 200 nM for human neutrophil elastase and porcine pancreatic elastase respectively |
| CSN11933 | Sivelestat sodium tetrahydrate | 201677-61-4 | Sivelestat sodium is a competitive inhibitor of human neutrophil elastase (IC50 44 nM Ki200 nM) also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse. |
| CSN17901 | Sivelestat sodium | 150374-95-1 | Sivelestat sodium is a competitive inhibitor of human neutrophil elastase (IC50 44 nM and Ki200 nM) and also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse. |
| CSN18744 | Sivelestat | 127373-66-4 | Sivelestat is a competitive inhibitor of human neutrophil elastase(IC50 44 nM and Ki200 nM) and also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse. |
| CSN19862 | Freselestat | 208848-19-5 | ONO 6818 is a high affinity and selective human neutrophil elastase 1 HNE1 inhibitor Ki 12 nM |
| CSN22112 | Lodelaben | 111149-90-7 | Lodelaben is a human neutrophil elastase inhibitor with an IC50 and Ki of 0.5 and 1.5 M, respectively. |
| CSN18079 | GW311616 hydrochloride | 197890-44-1 | GW311616A is a potent intracellular orally bioavailable long duration inhibitor of human neutrophil elastaseHNE with IC50 of 22 nM |
| CSN18080 | GW311616 | 198062-54-3 | GW311616 is a potent intracellular orally bioavailable long duration inhibitor of human neutrophil elastase HNE with IC50 of 22 nM and a free base form of GW311616A |
| CSN13283 | Docosyl Caffeate | 28593-92-2 | Docosyl caffeate is a natural product isolated and purified from the roots of Glycyrrhiza uralensis Fisch exhibiting potent elastase inhibitory activity. Docosyl caffeate shows moderate antioxidant activity in DPPH and ABTS scavenging assays. |
| CSN27395 | BAY-678 racemate | 675103-35-2 | BAY-678 racemate is a racemate of BAY-678. BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC). |
| CSN26231 | BAY-677 | 2117404-84-7 | BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY 677, is an inactive control for BAY 678 (B127615). |
| CSN18464 | Alvelestat | 848141-11-7 | Alvelestat is an inhibitor of neutrophil elastase NE with the pIC50 of 79 |
| CSN22338 | AE-3763 | 291778-77-3 | AE-3763 is a peptide-based human neutrophil elastase inhibitor with an IC50 of 29 nM. |
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