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eIF

eIF

Cat. No. Product Name CAS No. Information
CSN23286 SBI-0640756   2205871-61-8 SBI-0640756 is an inhibitor of eIF4G1 which can disrupt the function of eIF4F complex
CSN18917 6-Chloro-3-[3-(5-fluoropyridin-3-yl)acryloyl]-4-phenyl-1H-quinolin-2-one 1997370-71-4 SBI-0640756 is a first-in-class inhibitor that targets eIF4G1 and disrupts the eIF4F complex It can also suppress AKT and NF-kB signaling
CSN17259 Briciclib 865783-99-9 Briciclib is a small molecule that suppresses cyclin D1 accumulation in cancer cells
CSN19089 4E2RCat 432499-63-3 4E2RCat is an inhibitor of eIF4E-eIF4G interaction with an IC50 of 13.5 M.
CSN18215 4E1RCat   328998-25-0 4E1RCat blocks interaction between eIF4E:eIF4G and eIF4E:4E-BP1, prevents assembly of the eIF4F complex and inhibits cap-dependent translation with IC50 ~4 μM.
CSN67681 rel-Zotatifin 2098191-54-7
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