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E1/E2/E3 Enzyme

E1/E2/E3 Enzyme

Cat. No. Product Name CAS No. Information
CSN22266 E3 Ligand-Linker Conjugate 10 1957236-22-4 Thalidomide-O-amido-PEG4-C2-Amine is a PROTAC block consist of Thalidomide and a linker with Amine functional group for conjugation reactions.
CSN22272 E3 Ligand-Linker Conjugate 6 2022182-57-4 Thalidomide-O-amido-C3-Amine is a PROTAC block consist of Thalidomide linked to alkyl with Amine functional group for conjugation reactions.
CSN24768 Thalidomide-linker 2 2245697-85-0 Thalidomide-linker 2 is a PROTAC block consist of Thalidomide and a linker with Amine functional group for conjugation reactions.
CSN21083 TAK-243 1450833-55-2 TAK-243, also known as MLN7243 and AOB87172, is a small molecule inhibitor of ubiquitin-activating enzyme (UAE), with potential antineoplastic activity.
CSN17260 SZL P1-41 222716-34-9 SZL P1-41 is Skp2 inhibitor selectively suppresses Skp2 E3 ligase activity but not activity of other SCF complexes
CSN24085 Smurf1-IN-A01   1007647-73-5 Smurf1-IN-A01 is an inhibitor of negatively regulatory factor Smurf1 for promoting bone formation.
CSN25714 SMER 3 67200-34-4 SMER 3 is a selective inhibitor of yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo.
CSN18199 PRT4165   31083-55-3 PRT4165 an inhibitor of bim1 and ring1A could block PRC1 Polycomb-repressive complex 1-mediated H2A ubiquitylation
CSN22492 PROTAC Linker 1 1835705-53-7 PROTAC Linker 1 is a linker used to link the warhead and the E3 ligase ligand.
CSN19741 PK11195 85532-75-8 PK11195 is a 2Phenylindolylglyoxylyldipeptide Murine Double Minute2 MDM2Translocator Protein TSPOHuman Constitutive Androstane Receptor hCAR Inhibitor and is potentially useful for the Treatment of Gliomas
CSN21420 E3 ligase Ligand 2 5054-59-1 E3 ligase Ligand 2 is a thalidomide derivate for conjugation reactions of PROTAC, which can hijack cereblon as the E3 ubiquitin ligase component.
CSN21252 E3 Ligase Ligand 1A 1948273-02-6 E3 ligase Ligand 1A is a VH032 derivate for conjugation reactions of PROTAC, which can hijack VHL as the E3 ubiquitin ligase component.
CSN23876 COH000 1534358-79-6 COH000 is an irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme) with IC50 of 0.2 μM for SUMOylation in vitro.
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