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E1/E2/E3 Enzyme
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN22266 | E3 Ligand-Linker Conjugate 10 | 1957236-22-4 | Thalidomide-O-amido-PEG4-C2-Amine is a PROTAC block consist of Thalidomide and a linker with Amine functional group for conjugation reactions. |
| CSN22272 | E3 Ligand-Linker Conjugate 6 | 2022182-57-4 | Thalidomide-O-amido-C3-Amine is a PROTAC block consist of Thalidomide linked to alkyl with Amine functional group for conjugation reactions. |
| CSN24768 | Thalidomide-linker 2 | 2245697-85-0 | Thalidomide-linker 2 is a PROTAC block consist of Thalidomide and a linker with Amine functional group for conjugation reactions. |
| CSN21083 | TAK-243 | 1450833-55-2 | TAK-243, also known as MLN7243 and AOB87172, is a small molecule inhibitor of ubiquitin-activating enzyme (UAE), with potential antineoplastic activity. |
| CSN17260 | SZL P1-41 | 222716-34-9 | SZL P1-41 is Skp2 inhibitor selectively suppresses Skp2 E3 ligase activity but not activity of other SCF complexes |
| CSN24085 | Smurf1-IN-A01 | 1007647-73-5 | Smurf1-IN-A01 is an inhibitor of negatively regulatory factor Smurf1 for promoting bone formation. |
| CSN25714 | SMER 3 | 67200-34-4 | SMER 3 is a selective inhibitor of yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. |
| CSN18199 | PRT4165 | 31083-55-3 | PRT4165 an inhibitor of bim1 and ring1A could block PRC1 Polycomb-repressive complex 1-mediated H2A ubiquitylation |
| CSN22492 | PROTAC Linker 1 | 1835705-53-7 | PROTAC Linker 1 is a linker used to link the warhead and the E3 ligase ligand. |
| CSN19741 | PK11195 | 85532-75-8 | PK11195 is a 2Phenylindolylglyoxylyldipeptide Murine Double Minute2 MDM2Translocator Protein TSPOHuman Constitutive Androstane Receptor hCAR Inhibitor and is potentially useful for the Treatment of Gliomas |
| CSN21420 | E3 ligase Ligand 2 | 5054-59-1 | E3 ligase Ligand 2 is a thalidomide derivate for conjugation reactions of PROTAC, which can hijack cereblon as the E3 ubiquitin ligase component. |
| CSN21252 | E3 Ligase Ligand 1A | 1948273-02-6 | E3 ligase Ligand 1A is a VH032 derivate for conjugation reactions of PROTAC, which can hijack VHL as the E3 ubiquitin ligase component. |
| CSN23876 | COH000 | 1534358-79-6 | COH000 is an irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme) with IC50 of 0.2 μM for SUMOylation in vitro. |
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