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DYRK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN25712 | ProINDY | 719277-30-2 | ProINDY, the prodrug form of INDY, is an inhibitor of DYRK1A and DYRK1B. |
| CSN23650 | ML 315 | 1440251-53-5 | ML 315 is inhibitor of Clk and DYRK kinases with IC50s of 68, 68 and 231 nM for Clk1, Clk4 and Clk2, 282 and 1156 nM for Dyrk1A and Dyrk1B. |
| CSN17778 | Mirk-IN-1 | 1386979-55-0 | Mirk-IN-1 is a potent inhibitor of Dyrk1B (Mirk kianse) and Dyrk1A with IC50 of 6848 nM and 228 nM respectively. |
| CSN25711 | INDY | 1169755-45-6 | INDY is inhibitor of DYRK1B and DYRK1A with IC50 values of 0.23 and 0.24 μM respectively. |
| CSN17160 | ID-8 | 147591-46-6 | ID-8 is an inhibitor of DYRK inhibitor that can sustain embryonic stem cell self-renewal and survival without differentiation |
| CSN22843 | GSK-626616 | 1025821-33-3 | GSK 626616 is a potent and selective DYRK inhibitor with IC50 of 0.7 nM for DYRK3, similar potency for DYRK1 and 2. |
| CSN24803 | GNF4877 | 2041073-22-5 | GNF4877 is a potent DYRK1A and GSK3β inhibitor with IC50s of 6 nM and 16 nM, respectively |
| CSN22699 | AZ-Dyrk1B-33 | 1679330-37-0 | AZ Dyrk1B 33 is a potent and selective ATP-competitive Dyrk1B kinase inhibitor with IC50 of 7 nM. |
| CSN15862 | AZ191 | 1594092-37-1 | AZ 191 is a potent and selective DYRK1B inhibitor with IC50 of 17 nM in a cell-free assay about 5- and 110-fold selectivity over DYRK1A and DYRK2 respectively |
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