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DNA/RNA Synthesis

DNA/RNA Synthesis

Cat. No. Product Name CAS No. Information
CSN21982 Tetrahydrouridine 18771-50-1 Tetrahydrouridine is potent inhibitor of cytidine deaminase (CDA).
CSN25509 2'-Deoxy-2'-fluorouridine 784-71-4 RNA that was modified with 2'-deoxy-2'-fluorouridine yielded full length HIV-1 reverse transcription products, with complete fidelity in transcription. RNA analogue, FF, containing two molecules of 2'-deoxy-2'-alpha-fluorouridine in place of uridine efficiently inhibited the RNase L-catalyzed RNA cleavage reaction.
CSN21764 Nitracrine 4533-39-5 Nitracrine, an acridine antineoplastic used in ovarian tumors, can inhibit RNA synthesis. 
CSN25485 N,N-Dimethylguanosine 2140-67-2 N,N-Dimethylguanosine, an urinary nucleoside, is a primary degradation product of tRNA.
CSN19748 MS444 150045-18-4 MS-444 is a chrysanthone-like compound specifically inhibit the HuR from binding ARE-RNAs
CSN12580 Halofuginone Hydrobromide 64924-67-0 Halofuginone hydrobromide ointment may stop the growth of Kaposi's sarcoma by stopping blood flow to the tumor.
CSN23239 Guanosine   118-00-3 Guanosine is a purine nucleoside.
CSN25484 L-Guanosine 26578-09-6 Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. L-Guanosine is the L configuration of Guanosine.
CSN29504 Gemcitabine monophosphate 116371-67-6 Gemcitabine is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.
CSN10050 Folic Acid   59-30-3 Folic acid, a B vitamin, plays an important role in cell division and in the synthesis of amino acids and nucleic acids like DNA.
CSN22052 2'-Deoxypseudouridine 39967-60-7 Deoxypseudouridine is a nucleotide analog.
CSN16684 Daptomycin 103060-53-3 Daptomycin is a lipopeptide antimicrobial agent with activity against Gram-positive organisms including multi-resistant strains
CSN24306 Cytidine 65-46-3 Cytidine is a non-essential aminoacid.
CSN18773 CRT0044876   6960-45-8 CRT0044876 is a potent and selective APE1 inhibitor with IC50 of 3 M.
CSN25243 CMLD-2 958843-91-9 CMLD-2 competitively binds to Hu antigen R with Ki value of 350nM and disrupts the interaction of HuR and ARE (adenine- and uridine-rich element) of target mRNAs.
CSN12816 Bromodeoxyuridine   59-14-3 Bromodeoxyuridine is a thymidine analogue which is incorporated into DNA.
CSN10073 Blasticidin S HCl 3513-03-9 Blasticidin S inhibits protein synthesis by acting on the step of peptide transfer from peptidyl-sRNA to incoming aminoacyl-sRNA.
CSN27392 AV-153 free base 19350-66-4 AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity.
CSN18264 A2AR-Agonist-1 41552-95-8 A2AR-agonist-1 is a potent A2AR and ENT1 agonist with Ki of 4.39 and 3.47 for A2AR and ENT1.
CSN23866 8-Chloroadenosine 34408-14-5 8-Chloroadenosine is a cytotoxic nucleoside analog, it can inhibit RNA synthesis.
CSN25488 2-Amino-8-bromo-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one 4016-63-1 8-Bromoguanosine is a brominated derivative of guanosine.
CSN25518 6-Thioguanosine 85-31-4 6-thioguanosine is photosensitive molecule that photocrosslinks to both proteins and nucleic acids.
CSN12836 6-Mercaptopurine Monohydrate   6112-76-1 6-Mercaptopurine Monohydrate inhibits the de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA, it is a widely used antileukemic agent and immunosuppressive drug. 6-mercaptopurine was found to inhibit SARS-CoV PLpro.
CSN16373 6-Mercaptopurine   50-44-2 6-Mercaptopurine inhibits the de novo purine synthesis through interference with DNA and RNA synthesis, it's an immunosuppressive and antileukemic drug. 6-mercaptopurine was found to inhibit SARS-CoV PLpro.
CSN24938 5-Methylcytosine 554-01-8 5-Methylcytosine, a methylated form of the DNA base cytosine, is a major epigenetic mark in the nuclear DNA in mammals and may be involved in the regulation of gene transcription.
CSN24883 5-Methyl-2'-deoxycytidine 838-07-3 5-Methyl-2'-deoxycytidine (5-Me-dC) is a minor component found in most eukaryotic DNA.
CSN23335 5-methoxyflavone 42079-78-7 5-Methoxyflavone, belonged to Flavonoid family, is a DNA polymerase-beta inhibitor and neuroprotective agent against beta-amyloid toxicity. possess central nervous system (CNS) depressant effect mediated through the ionotropic GABAA receptors.
CSN25506 5-Iododeoxycytidine 611-53-0 5-Iododeoxycytidine is used in the construction of DNA oligomers.
CSN25526 5-Iodo-cytidine 1147-23-5 5-Iodocytidine is used for research in the field of nucleic acids and nucleic acid-protein interactions.
CSN25507 5-Fluorouridine 316-46-1 5-Fluorouridine is a metabolite of 5-fluorouracil with anticancer activity and cytotoxic activity. 5-fluorouridine inhibits rRNA synthesis of human colon carcinoma cells. 5-Fluorouridine exhibits cytotoxic effect on growth of L1210 cells with an IC50 of 2 nM. 5-Fluorouridine triphosphate acted as a potent competitive inhibitor of VPg uridylylation, the initial step of viral replication.
CSN25530 5-Fluorocytidine 2341-22-2 5-Fluorocytidine could replace cytidine and be incorporated into cellular RNAs or tRNAs.The bacterial enzyme cytosine deaminase has been used as a negative selection marker system. Cells that express cytosine deaminase convert 5-fluorocytosine to the toxic compound 5-fluorouracil, and transformed seedlings can thus be identified using medium containing 5-fluorocytosine.
CSN25480 5-Ethynyluridine 69075-42-9 5-Ethynyluridine is used to help detect RNA synthesis in cells by its biosynthetic incorporation into newly transcribed RNA. Once fed to cells, it is incorporated during active RNA synthesis and can then be detected using a copper-catalyzed click reaction with fluorescent dyes. The cells can then be analysed by fluorescence imaging, flow cytometry or high content imaging analysis.
CSN25508 5-Bromouridine 957-75-5 5-Bromouridine is used to label RNA in measurement of RNA production.
CSN25531 5-Bromocytidine 3066-86-2 5-Bromocytidine is a bromine substituted nucleoside.Its β-isomer derivative is a potent anti-HIV agent.
CSN27391 3,4-Dihydroxybenzylamine hydrobromide 16290-26-9 3,4-Dihydroxybenzylamine hydrobromide (NSC 263475 hydrobromide) is an improved dopamine analog cytotoxic and inhibits DNA polymerase activity in melanoma cells. 3,4-Dihydroxybenzylamine hydrobromide (NSC 263475 hydrobromide) displays growth inhibitory activity in melanoma cell lines with varying degrees of tyrosinase activity.
CSN25483 3'-O-Acetylthymidine 21090-30-2 3'-O-Acetylthymidine is a useful modified nucleoside.
CSN25481 3'-O-(TBDMS)Thymidine 40733-27-5 3'-O-(TBDMS)Thymidine is a useful modified nucleoside.
CSN25486 2-O-Methylguanosine 2140-71-8 2'-O-Methylguanosine is a modified nucleoside that is produced in tRNAs by the action of tRNA guanosine-2’-O-methyltransferase, using S-adenosyl-L-methionine as a substrate.
CSN25490 2'-O-(2-Methoxyethyl)-guanosine 473278-54-5 2'-O-(2-Methoxyethyl)-guanosine is a guanosine derivative as building blocks for cross-linking oligonucleotides.
CSN18758 2'-Deoxycytidine HCl 3992-42-5 2'-Deoxyguanosine HCl is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
CSN25516 2'-Deoxyadenosine 958-09-8 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
CSN25491 (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate 3181-38-2 2',3',5'-Tri-O-acetylinosine is an intermediate used for the synthesis of 6-substituted purine ribosides.
CSN25487 2-Amino-9-((2R,4R,5S)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one 22837-44-1
CSN25489 N-Isobutyrylguanosine 64350-24-9
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