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DNA/RNA Synthesis

DNA/RNA Synthesis

Cat. No. Product Name CAS No. Information
CSN24863 Uridine 5'-monophosphate 58-97-9 Uridine 5'-monophosphate is a nucleotide that is used as a monomer in RNA.
CSN16447 Uracil 66-22-8 Uracil is one of the four nucleobases in the nucleic acid of RNA can be used for drug delivery and as a pharmaceutical.
CSN19417 Tranexamic Acid(Random Configuration)   701-54-2 Tranexamic Acid (Random Configuration) is a medication used to treat or prevent excessive blood loss from major trauma, surgery, tooth removal, nose bleeds, and heavy menstruation.Inducing single-and double-strand breaks in DNA, base damage, and cell death.
CSN43681 TK216 1903783-48-1 TK-216, an analog of YK-4-279 inhibitor, is a potent and selective EWS-FLI1 inhibitor. TK-216 is in early clinical development for the treatment of Ewing sarcoma.
CSN21982 Tetrahydrouridine 18771-50-1 Tetrahydrouridine is potent inhibitor of cytidine deaminase (CDA).
CSN51391 FEN1-IN-SC13 2098776-03-3 SC13 specifically inhibits FEN1 activity. It suppresses cancer cell proliferation and induces chromosome instability and cytotoxicity in cells, as well as sensitizes cancer cells to DNA damage-inducing therapeutic modalities and impedes cancer progression in a mouse model.
CSN25509 2'-Deoxy-2'-fluorouridine 784-71-4 RNA that was modified with 2'-deoxy-2'-fluorouridine yielded full length HIV-1 reverse transcription products, with complete fidelity in transcription. RNA analogue, FF, containing two molecules of 2'-deoxy-2'-alpha-fluorouridine in place of uridine efficiently inhibited the RNase L-catalyzed RNA cleavage reaction.
CSN32990 RRM1 Inhibitor 1 2563874-93-9 Ribonucleoside-Diphosphate Reductase Large Subunit (RRM1) Inhibitors;TNF-alpha (ARE sequence)/ELAV-Like protein 1 (HuR) Interaction Inhibitors
CSN32991 RRM1 Inhibitor 2 2247176-87-8 Ribonucleoside-Diphosphate Reductase Large Subunit (RRM1) Inhibitors
CSN32994 RRM1 Inhibitor 5 1271734-91-8 Ribonucleoside-Diphosphate Reductase Large Subunit (RRM1) Inhibitors
CSN32992 RRM1 Inhibitor 3 1819992-33-0 Ribonucleoside-Diphosphate Reductase Large Subunit (RRM1) Inhibitors
CSN26441 RG7800 1449598-06-4 RG7800 HCl is an orally active SMN2 splicing modulator, with EC1.5xs of 23 nM and 87 nM for SMN2 splicing and SMN protein; has the potential to treat spinal muscular atrophy.
CSN17016 Resveratrol   501-36-0 Resveratrol is one of the numerous polyphenolic compounds found in several vegetal sources, has a wide spectrum of targets with IC50 of 0.8, 1, 3.3 and 5 M for Adenylyl cyclase, IKK, DNA polymerase and , respectively.
CSN11829 Raltitrexed 112887-68-0 Raltitrexed is an inhibitor of thymidylate synthase with IC50 of 9 nM in L1210 cell.
CSN16448 Psoralen   66-97-7 Psoralen, an ingredient from Fructus Psoraleae, intercalates with DNA, inhibiting DNA synthesis and cell division and showing anticancer activity.
CSN21764 Nitracrine 4533-39-5 Nitracrine, an acridine antineoplastic used in ovarian tumors, can inhibit RNA synthesis. 
CSN25485 N2,N2-Dimethylguanosine 2140-67-2 N,N-Dimethylguanosine, an urinary nucleoside, is a primary degradation product of tRNA.
CSN19748 MS-444 150045-18-4 MS-444 is a chrysanthone-like compound specifically inhibit the HuR from binding ARE-RNAs
CSN43591 Metarrestin 1443414-10-5 Metarrestin is a specific inhibitor of perinuclear compartment (PNC).
CSN22455 LysRs-IN-1 281676-77-5 LysRs-IN-1 is a Lysyl-tRNA synthetase (LysRs) inhibitor.
CSN33100 Indisulam analog 4 444579-59-3 Indisulam analog 4, as molecular glue, is especially effective and improves the half maximal effective concentration (EC50) to 1.21 µM in recruiting RBM39 to the DCAF15–DDB1–DDA1 complex.
CSN26246 HAMNO 138736-73-9 HAMNO is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response. It has shown to significantly inhibits colony formation when combined with etoposide.
CSN23239 Guanosine   118-00-3 Guanosine is a purine nucleoside.
CSN29504 Gemcitabine monophosphate 116371-67-6 Gemcitabine is a DNA synthesis inhibitor with IC50 of 50 nM, 40 nM, 18 nM and 12 nM in PANC1, MIAPaCa2, BxPC3 and Capan2 cells, respectively.
CSN22052 Deoxypseudouridine 39967-60-7 Deoxypseudouridine is a nucleotide analog.
CSN24877 Cytidine-5'-triphosphate disodium 36051-68-0 Cytidine 5'-triphosphate is a pyrimidine nucleoside triphosphate that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases.
CSN25243 CMLD-2 958843-91-9 CMLD-2 competitively binds to Hu antigen R with Ki value of 350nM and disrupts the interaction of HuR and ARE (adenine- and uridine-rich element) of target mRNAs.
CSN27392 AV-153 free base 19350-66-4 AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity.
CSN32946 COH-4 1190932-36-5 Apoptosis Inducers; RRM2 Expression Inhibitors
CSN32948 COH-20 1190932-37-6 Apoptosis Inducers; RRM2 Expression Inhibitors
CSN32947 COH-2 20217-22-5 Apoptosis Inducers; RRM2 Expression Inhibitors
CSN18264 A2AR-agonist-1 41552-95-8 A2AR-agonist-1 is a potent A2AR and ENT1 agonist with Ki of 4.39 and 3.47 for A2AR and ENT1.
CSN23866 8-Chloroadenosine 34408-14-5 8-Chloroadenosine is a cytotoxic nucleoside analog, it can inhibit RNA synthesis.
CSN25518 6-Thioguanosine 85-31-4 6-thioguanosine is photosensitive molecule that photocrosslinks to both proteins and nucleic acids.
CSN12836 6-Mercaptopurine hydrate   6112-76-1 6-Mercaptopurine Monohydrate inhibits the de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA, it is a widely used antileukemic agent and immunosuppressive drug. 6-mercaptopurine was found to inhibit SARS-CoV PLpro.
CSN16373 6-Mercaptopurine   50-44-2 6-Mercaptopurine inhibits the de novo purine synthesis through interference with DNA and RNA synthesis, it's an immunosuppressive and antileukemic drug. 6-mercaptopurine was found to inhibit SARS-CoV PLpro.
CSN24938 5-Methylcytosine 554-01-8 5-Methylcytosine, a methylated form of the DNA base cytosine, is a major epigenetic mark in the nuclear DNA in mammals and may be involved in the regulation of gene transcription.
CSN24883 5-Methyl-2'-deoxycytidine 838-07-3 5-Methyl-2'-deoxycytidine (5-Me-dC) is a minor component found in most eukaryotic DNA.
CSN25526 5-Iodocytidine 1147-23-5 5-Iodocytidine is used for research in the field of nucleic acids and nucleic acid-protein interactions.
CSN25530 5-Fluorocytidine 2341-22-2 5-Fluorocytidine could replace cytidine and be incorporated into cellular RNAs or tRNAs.The bacterial enzyme cytosine deaminase has been used as a negative selection marker system. Cells that express cytosine deaminase convert 5-fluorocytosine to the toxic compound 5-fluorouracil, and transformed seedlings can thus be identified using medium containing 5-fluorocytosine.
CSN25531 5-Bromocytidine 3066-86-2 5-Bromocytidine is a bromine substituted nucleoside.Its β-isomer derivative is a potent anti-HIV agent.
CSN27391 3,4-Dihydroxybenzylamine hydrobromide 16290-26-9 3,4-Dihydroxybenzylamine hydrobromide (NSC 263475 hydrobromide) is an improved dopamine analog cytotoxic and inhibits DNA polymerase activity in melanoma cells. 3,4-Dihydroxybenzylamine hydrobromide (NSC 263475 hydrobromide) displays growth inhibitory activity in melanoma cell lines with varying degrees of tyrosinase activity.
CSN18758 2'-Deoxycytidine hydrochloride 3992-42-5 2'-Deoxyguanosine HCl is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
CSN25516 2'-Deoxyadenosine 958-09-8 2'-Deoxyadenosine is a nucleoside adenosine derivative, pairing with deoxythymidine (T) in double-stranded DNA.
CSN25519 8-Mercaptoadenosine 3001-45-4
CSN27830 NSAH 1099592-35-4
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