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DNA-PK
| Cat. No. | Product Name | CAS No. | Information |
|---|---|---|---|
| CSN27247 | PIK-75 | 372196-67-3 | PIK-75 is a selective p110α inhibitor with IC50 of 5.8 nM with 200-fold more potently than p110β, and also potently inhibits DNA-PK with IC50 of 2 nM. |
| CSN18247 | PIK-75 hydrochloride | 372196-77-5 | PIK-75 is a selective p110 inhibitor with IC50 of 58 nM with 200-fold more potently than p110 and also potently inhibits DNA-PK with IC50 of 2 nM |
| CSN12265 | PI-103 | 371935-74-9 | PI-103 is a potent inhibitor with low IC50 values against recombinant PI3K isoforms p110alpha (IC50= 2 nM), p110beta (IC50= 3 nM), p110delta (IC50= 3 nM), and p110gamma (IC50= 15 nM), less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. It blocks autophagic flux. |
| CSN15991 | KU-57788 | 503468-95-9 | NU7441 is a potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 M in cell-free assays |
| CSN16116 | NU 7026 | 154447-35-5 | NU7026 is a potent and selective inhibitor of DNA-PK with IC50 of 023 M |
| CSN19819 | NU-7200 | 842122-14-9 | NU-7200 is a potent DNA-PK inhibitor with potential anticancer activity |
| CSN19818 | NU-7199 | 69541-04-4 | NU-7199 is a potent DNA-PK inhibitor with potential anticancer activity |
| CSN19817 | NU-7031 | 79105-88-7 | NU-7031 is a potent DNA-PK inhibitor with potential anticancer activity |
| CSN22555 | LTURM34 | 1879887-96-3 | LTURM34 shows potent inhibition of DNA-PK IC50 0034 M with excellent selectivity over the Class I PI3K isoforms IC50 all 5 M and inhibits the proliferation of a wide range of tumor cell lines |
| CSN22790 | DMNB | 20357-25-9 | DMNB is a volatile organic compound used as a detection taggant for explosives. |
| CSN17373 | Compound 401 | 168425-64-7 | Compound 401 is a DNA-PK synthetic inhibitor with IC50 of 028 M also targets mTOR |
| CSN17592 | CC-115 | 1228013-15-7 | CC-115 is an inhibitor of mTOR and DNA-PK with IC50 of 21 and 13 nM respectively |
| CSN17666 | CC-115 hydrochloride | 1300118-55-1 | CC-115 HCl is an inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM). |
| CSN10521 | Brivudine | 69304-47-8 | Brivudine is an antiviral drug acts by inhibiting replication of the target virus used in the treatment of Herpes Zoster |
| CSN24702 | AZD-7648 | 2230820-11-6 | AZD7648 is a highly potent and selective DNA-PK inhibitor with IC50 value of 92nM. |
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