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DNA-PK

DNA-PK

Cat. No. Product Name CAS No. Information
CSN27247 PIK-75   372196-67-3 PIK-75 is a selective p110α inhibitor with IC50 of 5.8 nM with 200-fold more potently than p110β, and also potently inhibits DNA-PK with IC50 of 2 nM.
CSN18247 PIK-75 hydrochloride   372196-77-5 PIK-75 is a selective p110 inhibitor with IC50 of 58 nM with 200-fold more potently than p110 and also potently inhibits DNA-PK with IC50 of 2 nM
CSN12265 PI-103 371935-74-9 PI-103 is a potent inhibitor with low IC50 values against recombinant PI3K isoforms p110alpha (IC50= 2 nM), p110beta (IC50= 3 nM), p110delta (IC50= 3 nM), and p110gamma (IC50= 15 nM), less potent to mTOR/DNA-PK with IC50 of 30 nM/23 nM. It blocks autophagic flux.
CSN15991 KU-57788 503468-95-9 NU7441 is a potent and selective DNA-PK inhibitor with IC50 of 14 nM and also inhibits PI3K with IC50 of 5 M in cell-free assays
CSN16116 NU 7026 154447-35-5 NU7026 is a potent and selective inhibitor of DNA-PK with IC50 of 023 M
CSN19819 NU-7200 842122-14-9 NU-7200 is a potent DNA-PK inhibitor with potential anticancer activity
CSN19818 NU-7199 69541-04-4 NU-7199 is a potent DNA-PK inhibitor with potential anticancer activity
CSN19817 NU-7031 79105-88-7 NU-7031 is a potent DNA-PK inhibitor with potential anticancer activity
CSN22555 LTURM34 1879887-96-3 LTURM34 shows potent inhibition of DNA-PK IC50 0034 M with excellent selectivity over the Class I PI3K isoforms IC50 all 5 M and inhibits the proliferation of a wide range of tumor cell lines
CSN22790 DMNB   20357-25-9 DMNB is a volatile organic compound used as a detection taggant for explosives.
CSN17373 Compound 401   168425-64-7 Compound 401 is a DNA-PK synthetic inhibitor with IC50 of 028 M also targets mTOR
CSN17592 CC-115 1228013-15-7 CC-115 is an inhibitor of mTOR and DNA-PK with IC50 of 21 and 13 nM respectively
CSN17666 CC-115 hydrochloride 1300118-55-1 CC-115 HCl is an inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).
CSN10521 Brivudine   69304-47-8 Brivudine is an antiviral drug acts by inhibiting replication of the target virus used in the treatment of Herpes Zoster
CSN24702 AZD-7648 2230820-11-6 AZD7648 is a highly potent and selective DNA-PK inhibitor with IC50 value of 92nM.
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