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DNA Methyltransferase

DNA Methyltransferase

Cat. No. Product Name CAS No. Information
CSN12234 Zebularine   3690-10-6 Zebularine is a DNA methylation inhibitor which forms a covalent complex with DNA methyltransferases, it also inhibits cytidinedeaminase with Ki of 2 M.
CSN15868 SGI-1027 1020149-73-8 SGI-1027 is a potent and selective inhibitor of DNA methyltransferase DNMT with IC50 of 6 8 75 M for DNMT1 DNMT3A and DNMT3B respectively
CSN16078 RG108   48208-26-0 RG108 is a DNA methyltransferase inhibitor with IC50 of 115 nM
CSN18251 Glucose-conjugated MGMT Inhibitor 382607-78-5 O6BTG-C8-Glu is a glucose-conjugated MGMT inhibitor with IC50 values of 32 nM in vitro and 10 nM on HeLa S3 cell and the parent compound O6BTGs IC50 is 9 nM in vitro
CSN11506 N-Acetylprocainamide 32795-44-1 N-Acetylprocainamide is the N-acetylated metabolite of Procainamide and is a Class III antiarrhythmic agent
CSN15937 Lomeguatrib 192441-08-0 Lomeguatrib an inhibitor of DNA repair protein O6-methylguanine-DNA methyltransferase MGMT with IC50 of 0009 M in cell-free extracts from HeLa S3 cells is a modified guanine base
CSN12608 Decitabine   2353-33-5 Decitabine is a potent inhibitor of DNA methyltransferase with IC50 of 438 nM and 4.38 nM in HL-60 and KG1a cells, respectively.
CSN18303 DC_517 500017-70-9 DC_517 is a selective non-nucleoside inhibitor of DNA methyltransferase 1 DNMT1 IC50 17 M
CSN18530 DC_05 890643-16-0 DC_05 is a non-nucleoside DNMT1 inhibitor IC50103 M with low micromolar IC50 values and significant selectivity toward other AdoMet-dependent protein methyltransferases
CSN13714 6-Thioguanine   154-42-7 6-Thioguanine belongs to the thiopurine family of drugs that also include mercaptopurine and azathioprine, which are examples of antimetabolites, and is a purine analogue of the nucleobase guanine.
CSN19354 5-Azacytidine   320-67-2 5-Azacytidine is a nucleoside analogue of cytidine that specifically inhibits DNA methylation by trapping DNA methyltransferases.
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