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DNA Methyltransferase

DNA Methyltransferase

Cat. No. Product Name CAS No. Information
CSN12234 Zebularine   3690-10-6 Zebularine is a DNA methylation inhibitor which forms a covalent complex with DNA methyltransferases, it also inhibits cytidinedeaminase with Ki of 2 M.
CSN16078 RG108   48208-26-0 RG108 is a DNA methyltransferase inhibitor with IC50 of 115 nM
CSN15937 Lomeguatrib 192441-08-0 Lomeguatrib an inhibitor of DNA repair protein O6-methylguanine-DNA methyltransferase MGMT with IC50 of 0009 M in cell-free extracts from HeLa S3 cells is a modified guanine base
CSN13714 6-Thioguanine   154-42-7 6-Thioguanine belongs to the thiopurine family of drugs that also include mercaptopurine and azathioprine, which are examples of antimetabolites, and is a purine analogue of the nucleobase guanine. It was found to inhibit SARS-CoV PLpro.
CSN25528 5−Fluoro−2'−deoxycytidine 10356-76-0 5−Fluoro−2'−deoxycytidine is a DNMT inhibitor which forms covalent links with the cysteine residue in the DNMT active site.
CSN20797 γ-Oryzanol   11042-64-1 -Oryzanol is a phytochemical with membrane antioxidant, naturally occurring in crude rice bran oil, can be used to treat hyperlipidemia, disorders of menopause and to increase the muscle mass.
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