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Diterpenoids

Diterpenoids

Cat. No. Product Name CAS No. Information
CSN14237 Villosin 160598-92-5 Villosin, a natural product isolated and purified from the herbs of Hedychium coronarium, shows inhibitory effects against nitric oxide production in LPS and IFN--induced RAW 264.7 murine macrophages with IC50 values of 5.99 1.20 ugmL and exhibits potent cytotoxic activity. It may be used as a potential lead molecule for antitumor therapeutic development.
CSN19412 Triptonide 38647-11-9 Triptonide, a natural product isolated and purified from the herb of Tripterygium wilfordii Hook.f. with antileukemic, antitumor, anti-inflammatory activities, is effective in the treatment of autoimmune diseases.
CSN19415 Triptolide 38748-32-2 Triptolide, a diterpene triepoxide extracted from the Chinese herb Tripterygium wilfordii, functions as a NF-B inhibitor with dual actions by disruption of p65CBP interaction and by reduction of p65 protein.
CSN14258 Taxinine 3835-52-7 Taxinine, a natural product isolated and purified from the seeds of Tuxus mairei., can inhibit the drug transport by P-glycoprotein in multidrug-resistant cells
CSN14256 Taxinine M 135730-55-1 Taxinine M is a chemotherapy agent isolated and purified from the seeds of Chinese yew Taxus chinensis.
CSN19410 Tanshinone IIA   568-72-9 Tanshinone IIA is a naturally occuring cardioprotective agent which can inhibit NF-B and AP-1 DNA binding and display antioxidant and anti-inflammatory properties.
CSN12435 Tanshinone I 568-73-0 Tanshinone I, an active principle isolated from the roots of Salvia miltiorrhiza (Danshen), is an inhibitor of type IIA human recombinant sPLA2 and rabbit recombinant cPLA2 with IC50s of 11 M and 82 M, respectively, is structurally similar to tanshinone IIA and may possess similar cytotoxic effects on tumor cells.
CSN14777 Tanshinlactone 105351-70-0 Tanshinlactone is a natural product isolated and purified from the roots of Salvia miltiorrhiza.
CSN11984 Stevioside     57817-89-7 Stevioside, a natural product isolated and purified from the leaves of Stevia rebaudiana, is a safe natural sweetener, has no allergic reactions, suited for both diabetics, and PKU patients, as well as for obese persons intending to lose weight by avoiding sugar supplements in the diet. Stevioside also exerts anti-inflammatory and anti-apoptotic properties by inhibiting the release of cytokines and the activation of TLR2 and proteins of the NF-B and MAPK signaling pathways, as well as caspase-3 and Bax. Stevioside and steviol attenuate LPS-induced pro-inflammatory cytokine productions by affecting cytokine gene expression via IBNF-B signalling pathway.
CSN17003 Steviol   471-80-7 Steviol is the aglycon derivative of steviol glycosides, which are natural sweeteners isolated from S. rebaudiana. Steviol inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity.
CSN11931 Sisomicin Sulfate   53179-09-2 Sisomicin Sulfate is a broad-spectrum aminoglycoside antibiotic, strucurally similar to gentamicin and most active against gram-positive bacteria.
CSN15331 Scutebarbatine A 176520-13-1 Scutebarbatine A, a natural product isolated and purified from the herbs of Scutellaria barbata D. Don, shows significant antitumor effects on A549 cells in vivo and in vitro via mitochondria-mediated apoptosis by up-regulating expressions of caspase-3 and 9, and down-regulating Bcl-2, and a significant ability to protect cells against H2O2 with ED50 values of 5.0 and 16.8 uM, respectively.
CSN11871 Rubusoside 64849-39-4 Rubusoside is a natural sweetener and a solubilizing agent with antiangiogenic and antiallergic properties.
CSN11947 Quassin 76-78-8 Quassin, a natural product isolated and purified from the barks of Quassia amara L., inhibits the steroidogenesis in rat Leydig cells in vitro, and has anti-larval activity at a concentration of 6 ppm.
CSN14451 Przewaquinone A 76843-23-7 Przewaquinone A is a natural product isolated and purified from the roots of Salvia miltiorrhiza with antitumor activity.
CSN14234 Przewalskin 119400-87-2 Przewalskin is a natural product isolated and purified from the roots of Salvia miltiorrhiza with antitumor and anti-HIV activities.
CSN11714 Phytol   150-86-7 Phytol can activite PPAR and attenuate the inflammatory response by inhibiting neutrophil migration and oxidative stress. Phytol is isolated from the leaves of black tea and acts as an aromatic ingredient.
CSN11702 Phorbol 13-Acetate 32752-29-7 Phorbol 13-acetate is a reference compound for studying 12-deacylation of phorbol 12-myristate 13-acetate.
CSN10959 Ethyl Palmitate 628-97-7 Palmitic acid is a common 16-carbon saturated fat that represents 10-20 of the normal human dietary fat intake.
CSN20394 Ovatodiolide 3484-37-5 Ovatodiolide is a macrocyclic diterpenoid isolated from Anisomeles indica, showing therapeutic potential for the treatment of allergic asthma.
CSN19419 Oridonin   28957-04-2 Oridonin is an antitumor agent, a diterpenoid purified from Rabdosia rubescens.
CSN14103 Kaurenoic Acid 6730-83-2 Kaurenoic Acid is a natural product isolated and purified from the herbs of Croton antisyphiliticus with anti-inflammatory property, the mechanisms may through inhibition of iNOS and COX-2 expression. Kaurenoic acid is an inducer of apoptosis, which is part of the innate mechanism of cell defense against neoplasia. Kaurenoic acid from A. continentalis may be a useful agent for inhibiting the cariogenic properties of S. mutans.
CSN15063 Jolkinol A 62820-11-5 Jolkinol A, a natural product isolated and purified from the seeds of Euphorbia lathyris L., can inhibit both MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) cell lines, with GI50 values ranging between 40.9 mM and 95.3 mM.
CSN11232 Isosteviol   27975-19-5 Isosteviol, an antihyperglycemic agent, is a natural product isolated and purified from the herbs of Stevia rebaudiana with anti-hyperglycemic, anti-hypertensive, anti-tumor, anti-inflammatory, and antioxidant properties.
CSN11864 Gum Rosin   8050-09-7 Gum rosin and wood rosin in Tako-no-Suidashi ointment have an effect on allergic contact dermatitis.
CSN12568 Ginkgolide A 15291-75-5 Ginkgolide A is an antagonist of g-aminobutyric acid (GABA) with Ki of 14.5 M and also can activate PAF. It is purified from the leaves of ginkgo biloba tree.
CSN16500 Dihydrotanshinone I 87205-99-0 Dihydrotanshinone I, a natural product isolated and purified from the roots of Salvia miltiorrhiza Bge., exhibits dose-dependent inhibition towards HLM-catalyzed propofol glucuronidation.
CSN10311 Deoxyandrographolide 79233-15-1 Deoxyandrographolide is a natural compound extracted from the herbs of Andrographis paniculata (Burm. f.) Nees, promotes glucose uptake through glucose transporter-4 translocation to plasma membrane in L6 myotubes and exerts antihyperglycemic effect in vivo.
CSN10310 Dehydroandrographolide   134418-28-3 Dehydroandrographolide is extracted from herbal medicine Andrographis paniculata (Burm f) Nees and alleviates oxidative stress in LPS-induced acute lung injury possibly by inactivating iNOS.
CSN19484 Deacetyltaxol   78432-77-6 Deacetyltaxol is a natural product isolated and purified from the barks of Taxus chinensis (Pilger) Rehd. with cytotoxicity in human glial and neuroblastoma cell-lines.
CSN10749 Darutigenol 5940-00-1 Darutigenol, a natural product isolated and purified from the herb of Siegesbeckia orientalis., has obvious antithrombotic effect, its mechanism may be related to inhibition of platelet aggregation and adhesion.
CSN10597 Cephalomannine 71610-00-9 Cephalomannine, a natural product isolated and purified from the barks of Cephalotaxus sinensis (Rehd. et Wils.) Li, is a taxol derivative with antitumor, antiproliferative properties.
CSN10554 Carnosol 5957-80-2 Carnosol, a natural product isolated and purified from the herbs of Rosmarinus officinalis L., enhances the sensitivity of chemoresistant cancer cells to chemotherapeutic agents. Carnosol may as an agonist of TRPA1 with an EC50 value of 12.46 M.
CSN13458 Bruceine D   21499-66-1 Bruceine D, a natural product isolated and purified from the barks of Ailanthus altissima, may have the potential to be used as a natural viricide, or a lead compound for viricides, inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW1990 and CAPAN-1, and induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.
CSN19420 Andrographolide   5508-58-7 Andrographolide is a naturally occuring NF-B inhibitor.
CSN15042 Adenanthin 111917-59-0 Adenanthin, a natural product isolated and purified from the herb of Rabdosia adenantha with antiinflammatory, antitumour, bacteriostatic, and antileukemic activities, is an NF-B and nucleophilic cysteines inhibitor, and can serve as the development of Prx I and Prx IItargeted therapeutic agents.
CSN10195 Abietic Acid 514-10-3 Abietic acid is a PPAR dual activator to inhibit UVB-induced MMP-1 expression and age-related inflammation by suppressing NF-B and the MAPKAP-1 pathway, its a natural product isolated and purified from the herbs of Pinus massoniana which can be used not only for anti-inflammation but also for regulating lipid metabolism and atherosclerosis.
CSN15049 Abiesadine N 1159913-80-0 Abiesadine N is a natural product isolated and purified from the barks of Pinus yunnanensis.
CSN13461 7-Epitaxol     105454-04-4 7-Epitaxol is a natural product isolated and purified from the barks of Taxus chinensis (Pilger) Rehd. which is the major derivative of taxol found in cells and that its presence does not alter, in a major way, the overall biological activity of taxol.
CSN14257 7-Epi 10-Desacetyl Paclitaxel 78454-17-8 7-Epi 10-desacetyl paclitaxel is a paclitaxel impurity. The compound, originally isolated from Taxus yunnanensis, has shown potential growth inhibitory activities against human cancer cells.
CSN14248 Euphorbia Factor L3 218916-52-0 5,15-Diacetyl-3-benzoyllathyrol, a natural product isolated and purified from the seeds of Euphorbia lathyris L., is one of the lathyrane diterpenoids with anti-cancer activity.
CSN14807 2-Deacetoxytaxinine J 119347-14-7 2-deacetoxytaxinine J, a natural product isolated and purified from plant, has an anticancer activity in vitro and in vivo.
CSN13260 2,6,16-Kauranetriol 2-O-beta-D-Allopyranoside 195735-16-1 2,6,16-Kauranetriol 2-O-beta-D-allopyranoside is a natural product isolated and purified from the herbs of Pteris cretica.
CSN13259 2,16,19-Kauranetriol 2-O-beta-D-Allopyranosid 195723-38-7 2,16,19-Kauranetriol 2-O-beta-D-allopyranosid is a natural product isolated and purified from the herbs of Pteris cretica.
CSN14790 18-Nor-4,15-Dihydroxyabieta-8,11,13-Trien-7-One 213329-46-5 18-Nor-4,15-dihydroxyabieta-8,11,13-trien-7-one, a natural product isolated and purified from the barks of Pinus yunnanensis, shows moderate cytotoxicity against a human lung carcinoma cell line.
CSN19449 10-Deacetylbaccatin III   32981-86-5 10-Deacetylbaccatin-III is an intermediate for taxol analog preparations.
CSN11720 Pimaric Acid 127-27-5
CSN16599 Crocin 42553-65-1
CSN14246 Nagilactone C 24338-53-2
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