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Diterpenoids

Diterpenoids

Cat. No. Product Name CAS No. Information
CSN14237 Villosin 160598-92-5 Villosin, a natural product isolated and purified from the herbs of Hedychium coronarium, shows inhibitory effects against nitric oxide production in LPS and IFN--induced RAW 264.7 murine macrophages with IC50 values of 5.99 1.20 ugmL and exhibits potent cytotoxic activity. It may be used as a potential lead molecule for antitumor therapeutic development.
CSN14785 Triptoquinone B 142937-50-6 Triptoquinone B, a natural product isolated and purified from the vines of Tripterygium wilfordii with immunosuppressive acitivity, is an interleukin-1 inhibitor, showing extremely potent inhibitory activities against interleukin-l and releases for human peripheral mononticlear cells.
CSN19415 Triptolide 38748-32-2 Triptolide, a diterpene triepoxide extracted from the Chinese herb Tripterygium wilfordii, functions as a NF-B inhibitor with dual actions by disruption of p65CBP interaction and by reduction of p65 protein.
CSN14774 Taxinine B 18457-44-8 Taxinine B, a natural product isolated and purified from the barks of Taxus chinensis, can inhibit the drug transport by P-glycoprotein in multidrug-resistant cells, and shows stronger inhibitory effects than acetylsalicylic acid (ASA) on platelet aggregation induced by arachidonic acid (AA).
CSN12435 Tanshinone I 568-73-0 Tanshinone I, an active principle isolated from the roots of Salvia miltiorrhiza (Danshen), is an inhibitor of type IIA human recombinant sPLA2 and rabbit recombinant cPLA2 with IC50s of 11 M and 82 M, respectively, is structurally similar to tanshinone IIA and may possess similar cytotoxic effects on tumor cells.
CSN11984 Stevioside     57817-89-7 Stevioside, a natural product isolated and purified from the leaves of Stevia rebaudiana, is a safe natural sweetener, has no allergic reactions, suited for both diabetics, and PKU patients, as well as for obese persons intending to lose weight by avoiding sugar supplements in the diet. Stevioside also exerts anti-inflammatory and anti-apoptotic properties by inhibiting the release of cytokines and the activation of TLR2 and proteins of the NF-B and MAPK signaling pathways, as well as caspase-3 and Bax. Stevioside and steviol attenuate LPS-induced pro-inflammatory cytokine productions by affecting cytokine gene expression via IBNF-B signalling pathway.
CSN17003 Steviol   471-80-7 Steviol is the aglycon derivative of steviol glycosides, which are natural sweeteners isolated from S. rebaudiana. Steviol inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. Steviol glycosides enhance pancreatic beta-cell function and taste sensation by potentiation of TRPM5 channel activity.
CSN14234 Przewalskin 119400-87-2 Przewalskin is a natural product isolated and purified from the roots of Salvia miltiorrhiza with antitumor and anti-HIV activities.
CSN14239 Pinusolide 31685-80-0 Pinusolide, a natural potent and specific PAF antagonist isolated and purified from the barks of Biota orientalis L., inhibits 5-lipoxygenase (5-LO)-dependent leukotriene C4 (LTC4) generation in immunoglobulin E (IgE)Ag-induced bone marrow-derived mast cells (BMMCs) in a concentration-dependent manner.
CSN11702 Phorbol 13-Acetate 32752-29-7 Phorbol 13-acetate is a reference compound for studying 12-deacylation of phorbol 12-myristate 13-acetate.
CSN10959 Ethyl Palmitate 628-97-7 Palmitic acid is a common 16-carbon saturated fat that represents 10-20 of the normal human dietary fat intake.
CSN19419 Oridonin   28957-04-2 Oridonin is an antitumor agent, a diterpenoid purified from Rabdosia rubescens.
CSN14796 Nagilactone B 19891-51-1 Nagilactone B, a natural product isolated and purified from the herbs of Podocarpus neriifolius, selectively activates LXR in macrophages and induces ABCA1- and ABCG1-mediated cholesterol efflux while exerting minimal effects on lipogenesis and lipid accumulation in liver, resulting in regression of atherosclerosis, and therefore might be a promising strategy for therapeutics.
CSN15324 Kongensin A 885315-96-8 Kongensin A, a natural product isolated and purified from the herbs of Croton cascarilloides, is an effective heat shock protein 90 (HSP90) inhibitor that has potential anti-necroptosis and anti-inflammation applications.
CSN14103 Kaurenoic Acid 6730-83-2 Kaurenoic Acid is a natural product isolated and purified from the herbs of Croton antisyphiliticus with anti-inflammatory property, the mechanisms may through inhibition of iNOS and COX-2 expression. Kaurenoic acid is an inducer of apoptosis, which is part of the innate mechanism of cell defense against neoplasia. Kaurenoic acid from A. continentalis may be a useful agent for inhibiting the cariogenic properties of S. mutans.
CSN11232 Isosteviol   27975-19-5 Isosteviol, an antihyperglycemic agent, is a natural product isolated and purified from the herbs of Stevia rebaudiana with anti-hyperglycemic, anti-hypertensive, anti-tumor, anti-inflammatory, and antioxidant properties.
CSN19405 Honokiol   35354-74-6 Honokiol inhibits Akt activation and enhances ERK1ERK2 phosphorylation, is a hydroxylated biphenyl compound isolated from the Chinese herb Magnolia officinalis with anticancer activities in a variety of cancer cell lines.
CSN11864 Gum Rosin   8050-09-7 Gum rosin and wood rosin in Tako-no-Suidashi ointment have an effect on allergic contact dermatitis.
CSN19411 Ginkgolide C   15291-76-6 Ginkgolide C can enhance the cardiac function of rats in the body, is a flavone isolated from Ginkgo biloba leaves.
CSN16500 Dihydrotanshinone I 87205-99-0 Dihydrotanshinone I, a natural product isolated and purified from the roots of Salvia miltiorrhiza Bge., exhibits dose-dependent inhibition towards HLM-catalyzed propofol glucuronidation.
CSN10311 Deoxyandrographolide 79233-15-1 Deoxyandrographolide is a natural compound extracted from the herbs of Andrographis paniculata (Burm. f.) Nees, promotes glucose uptake through glucose transporter-4 translocation to plasma membrane in L6 myotubes and exerts antihyperglycemic effect in vivo.
CSN10310 Dehydroandrographolide   134418-28-3 Dehydroandrographolide is extracted from herbal medicine Andrographis paniculata (Burm f) Nees and alleviates oxidative stress in LPS-induced acute lung injury possibly by inactivating iNOS.
CSN19484 Deacetyltaxol   78432-77-6 Deacetyltaxol is a natural product isolated and purified from the barks of Taxus chinensis (Pilger) Rehd. with cytotoxicity in human glial and neuroblastoma cell-lines.
CSN10749 Darutigenol 5940-00-1 Darutigenol, a natural product isolated and purified from the herb of Siegesbeckia orientalis., has obvious antithrombotic effect, its mechanism may be related to inhibition of platelet aggregation and adhesion.
CSN19905 Crocin II   55750-84-0 Crocin, a natural product with anti-inflammatory, antihyperlipidemic, antidepressant and anti-apoptotic effects, can ameliorate CCl4-induced liver injury via inhibition of inflammatory cytokines, caspase3 and oxidative stress along with modulation of liver metabolizing enzymes favoring elimination of CCl4 toxic metabolite, its isolated and purified from the stigma of Crocus sativus L..
CSN10597 Cephalomannine 71610-00-9 Cephalomannine, a natural product isolated and purified from the barks of Cephalotaxus sinensis (Rehd. et Wils.) Li, is a taxol derivative with antitumor, antiproliferative properties.
CSN10554 Carnosol 5957-80-2 Carnosol, a natural product isolated and purified from the herbs of Rosmarinus officinalis L., enhances the sensitivity of chemoresistant cancer cells to chemotherapeutic agents. Carnosol may as an agonist of TRPA1 with an EC50 value of 12.46 M.
CSN20512 Cafestol 469-83-0 Cafestol is a bioactive substance isolated and extracted from coffee with potential medical uses.
CSN13458 Bruceine D   21499-66-1 Bruceine D, a natural product isolated and purified from the barks of Ailanthus altissima, may have the potential to be used as a natural viricide, or a lead compound for viricides, inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW1990 and CAPAN-1, and induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.
CSN15373 Aphadilactone C 1522004-70-1 Aphadilactone C is a naturla product isolated and purified from Aphanamixis grandifolia with DGAT inhibitory and antimalarial activities.
CSN15374 Aphadilactone B 1522004-68-7 Aphadilactone B is a naturla product isolated and purified from Aphanamixis grandifolia with DGAT inhibitory and antimalarial activities.
CSN15042 Adenanthin 111917-59-0 Adenanthin, a natural product isolated and purified from the herb of Rabdosia adenantha with antiinflammatory, antitumour, bacteriostatic, and antileukemic activities, is an NF-B and nucleophilic cysteines inhibitor, and can serve as the development of Prx I and Prx IItargeted therapeutic agents.
CSN10195 Abietic Acid 514-10-3 Abietic acid is a PPAR dual activator to inhibit UVB-induced MMP-1 expression and age-related inflammation by suppressing NF-B and the MAPKAP-1 pathway, its a natural product isolated and purified from the herbs of Pinus massoniana which can be used not only for anti-inflammation but also for regulating lipid metabolism and atherosclerosis.
CSN15049 Abiesadine N 1159913-80-0 Abiesadine N is a natural product isolated and purified from the barks of Pinus yunnanensis.
CSN13461 7-Epitaxol     105454-04-4 7-Epitaxol is a natural product isolated and purified from the barks of Taxus chinensis (Pilger) Rehd. which is the major derivative of taxol found in cells and that its presence does not alter, in a major way, the overall biological activity of taxol.
CSN15356 6alpha-Hydroxycleroda-3,13-Dien-16,15-Olid-18-Oic Acid 771493-42-6 6alpha-hydroxycleroda-3,13-dien-16,15-olid-18-oic acid is an alpha- glucosidase inhibitory constituent from Duranta repens, and is one alpha- glucosidase inhibitory constituent from Duranta repens.
CSN13308 2,6,16-Kauranetriol 41530-90-9 2,6,16-Kauranetriol is a natural product isolated and purified from the herbs of Pteris cretica.
CSN13260 2,6,16-Kauranetriol 2-O-beta-D-Allopyranoside 195735-16-1 2,6,16-Kauranetriol 2-O-beta-D-allopyranoside is a natural product isolated and purified from the herbs of Pteris cretica.
CSN13314 2,16-Kauranediol 2-O-beta-D-Allopyranoside 474893-07-7 2,16-Kauranediol 2-O-beta-D-allopyranoside is a natural product isolated and purified from the herbs of Pteris cretica.
CSN13259 2,16,19-Kauranetriol 2-O-beta-D-Allopyranosid 195723-38-7 2,16,19-Kauranetriol 2-O-beta-D-allopyranosid is a natural product isolated and purified from the herbs of Pteris cretica.
CSN13323 16-Kaurene-2,6,15-Triol 53452-32-7 16-Kaurene-2,6,15-triol is a natural product isolated and purified from the herbs of Rabdosia amethystoides.
CSN14100 15-Hydroxydehydroabietic Acid 54113-95-0 15-Hydroxydehydroabietic acid is a natural product isolated and purified from the branch of Platycladus orientalis with a promising alpha-glucosidase inhibitory and significant antibacterial activities.
CSN13346 13-Hydroxy-8,11,13-Podocarpatrien-18-Oic Acid 61597-83-9 13-Hydroxy-8,11,13-podocarpatrien-18-oic acid is a natural product isolated and purified from the herbs of Pinus kesiya var. langbianensis.
CSN13333 11,15-Dihydroxy-16-Kauren-19-Oic Acid 57719-76-3 11,15-Dihydroxy-16-kauren-19-oic acid is a natural product isolated and purified from the herbs of Cerbera manghas.
CSN14581 Eriocalyxin B 84745-95-9
CSN11720 Pimaric Acid 127-27-5
CSN16599 Crocin 42553-65-1
CSN14246 Nagilactone C 24338-53-2
CSN14101 14-Deoxy-11,12-Didehydroandrographolide 42895-58-9
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