Welcome to CSNpharm! For Research Use Only!
Home Compound Arrays Promotion +1-708-781-1677 sales@csnpharm.com    

Dehydrogenase

Dehydrogenase

Cat. No. Product Name CAS No. Information
CSN13699 Teriflunomide   163451-81-8 Teriflunomide, the active metabolite of an approved antirheumatic drug leflunomide, is an emerging oral therapy for multiple sclerosis (MS). It reversibly inhibits dihydroorotate dehydrogenase, the rate-limiting step in the de novo synthesis of pyrimidines.
CSN11548 Teriflunomide(Random Configuration)   108605-62-5 Teriflunomide, the active metabolite of an approved antirheumatic drug leflunomide, is an emerging oral therapy for multiple sclerosis (MS). It reversibly inhibits dihydroorotate dehydrogenase, the rate-limiting step in the de novo synthesis of pyrimidines.
CSN22561 Sodium 2,2-dichloroacetate   2156-56-1 Sodium 22-dichloroacetate is a specific inhibitor of pyruvate dehydrogenase kinase PDK with IC50s of 183 and 80 M for PDK2 and PDK4 respectively with tumor growth inhibition properties
CSN22939 (R)-GNE-140 2003234-63-5 R-GNE-140 is a potent lactate dehydrogenase A LDHA inhibitor with IC50s of 3 nM and 5 nM for LDHA and LDHB respectively
CSN24124 Pyrazinecarboxylic acid 98-97-5 Pyrazinoic Acid inhibits Mycobacterial Coenzyme A biosynthesis by binding to aspartate decarboxylase PanD.
CSN21792 Phenylglyoxal hydrate   1075-06-5 Phenylglyoxal Hydrate is a potent inhibitor of mitochondrial aldehyde dehydrogenase ALDH binding the arginine residues in purified Hageman factor HF Factor XII and causes inhibition of its coagulant properties
CSN23240 Oxalacetic Acid 328-42-7 Oxaloacetic Acid substrate for malate dehydrogenase and oxaloacetate decarboxylase. Oxaloacetic Acid is an inhibitor of SDH.
CSN19396 Mycophenolic Acid   24280-93-1 Mycophenolic Acid is an an immunosuppresant agent with a potent inibition of IMPDH (inosine monophosphate dehydrogenase) and potent anti-proliferative activity, it can be isolated from several Penicillium species.
CSN16132 Mycophenolate Mofetil   128794-94-5 Mycophenolate mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase III with IC50 of 39 nM and 27 nM, respectively.
CSN16462 Leflunomide   75706-12-6 Leflunomide is a dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 2.5 M, it is a disease-modifying antirheumatic drug (DMARD) and inhibits de novo pyrimidine synthesis.
CSN11234 Isovaleramide   541-46-8 Isovaleramide a liver alcohol dehydrogenases inhibitor is an anticonvulsant molecule isolated from Valeriana pavonii
CSN26126 HQNO 341-88-8 HQNO is a potent respiratory inhibitor produced by Pseudomonas aeruginosa. It is a competitive inhibitor of quinone and targets the Q-site of NDH-2.
CSN16654 Gimeracil   103766-25-2 Gimeracil is an inhibitor of dihydropyrimidine dehydrogenase DPYD which degrades pyrimidine including 5-fluorouracil in the blood and inhibits homologous recombination
CSN19521 Fomepizole   7554-65-6 Fomepizole is a competitive inhibitor of the enzyme alcohol dehydrogenase which plays a key role in the metabolism of ethylene glycol and methanol
CSN20383 Crocetin 27876-94-4 Crocetin a saffron derivative is an inhibitor of human lactate dehydrogenase 5 in the antiglycolytic approach against cancer
CSN15809 CPI-613   95809-78-2 CPI-613 is an E1 pyruvate dehydrogenase PDH modulator that prevents cancer cells from metabolizing glucose for energy CPI-613 has been granted orphan drug status by the US FDA for pancreatic cancer
CSN16289 BVT 2733 376640-41-4 BVT 2733 is a small molecule, non-steroidal, isoform-selective inhibitor of 11beta-hydroxysteroid dehydrogenase type 1(11-HSD1).
CSN25384 Brequinar 96187-53-0 Brequinar (DUP785) is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 5.2 nM for human DHODH. Brequinar has potent activities against a broad spectrum of viruses.
CSN25625 BAY 2402234 2225819-06-5 BAY 2402234 is a novel and selective dihydroorotate dehydrogenase (DHODH) inhibitor. It potently inhibited proliferation of AML cell lines in the sub-nanomolar to low-nanomolar range in vitro and exhibited strong in vivo anti-tumor efficacy in monotherapy in several subcutaneous and disseminated AML xenografts as well as AML patient-derived xenograft (PDX) models.
CSN25633 AZ 33 1370290-34-8 AZ 33 is a Lactate Dehydrogenase A inhibitor with IC50 value of 0.5μM.
CSN23342 3-Methylpyrazole   1453-58-3 3-Methylpyrazole is a nitrification inhibitor of nitrification in soil
CSN27552 2-Bromoacetamide 683-57-8 2-Bromoacetamide can inactivate alcohol dehydrogenase.
CSN25383 Brequinar sodium 96201-88-6
<< PREV 1 2 NEXT >>