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CRM1

CRM1

Cat. No. Product Name CAS No. Information
CSN17781 Verdinexor 1392136-43-4 Verdinexor is an orally bioavailable selective inhibitor of nuclear export (SINE), inhibits nuclear export protein Exportin 1 (XPO1/CRM1) against canine tumor cell lines and also reduce influenza virus replication in vitro and in vivo.
CSN19083 KPT-8602 Z-Isomer 1642300-78-4 KPT-8602 Z-isomer is an isomer of KPT-8602 which is highly specific for XPO1 inhibition and demonstrates potent anti-leukemic activity
CSN19082 KPT-8602 1642300-52-4 KPT-8602 is a second-generation and oral acitve exportin-1 XPO1CRM1 inhibitor with IC50 of 20211nM in 10 AML cell lines.
CSN16156 KPT-330   1393477-72-9 KPT-330 analog of KPT-185 is an orally bioavailable selective CRM1 inhibitor
CSN17829 KPT-276 1421919-75-6 KPT-276 analog of KPT-185 is a CRM1 blocker and acts as an orally bioavailable selective inhibitor of nuclear export SINE by irreversibly binding to CRM1
CSN17700 KPT-185 1333151-73-7 KPT-185 is a selective CRM1 inhibitor that induces growth inhibition and apoptosis in a panel of NHL cell lines with a median IC50 25 nM
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