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The cAMP-response element binding protein (CREB) is localized in the nucleus and acts as a transcription factor, which binds to the cAMP response element (CRE) of the promoters of its target genes, upon phosphorylation at Ser133 by different receptor-activated protein kinases, such as protein kinase A (PKA), calmodulin-dependent protein kinase (CaMK), mitogen-activated protein kinases (MAPK), and other kinases.

CREB

Cat. No. Product Name CAS No. Information
CSN24157 666-15 1433286-70-4 666-15 is a potent and selective CREB inhibitor with IC50 value of 81nM.
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