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COX

COX

Cat. No. Product Name CAS No. Information
CSN12344 Valdecoxib   181695-72-7 Valdecoxib is a potent COX inhbitor that selectively inhibitors COX-2 with IC50 of 5 nM.
CSN12172 Ufenamate   67330-25-0 Ufenamate is a COX inhibitor, used as a topical analgesic.
CSN12136 Tribenoside 10310-32-4 Tribenoside is a vasoprotective and a mixture of the - und -anomers.
CSN12107 Tolfenamic Acid   13710-19-5 Tolfenamic acid is a selective COX2 inhibitor with IC50 of 13.49 M, its a non-steroidal anti-inflammatory drugs (NSAIDs).
CSN12050 Tenoxicam   59804-37-4 Tenoxicam is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.
CSN12019 Suprofen   40828-46-4 Suprofen is a COX12 inhibitor and a non-steroidal anti-inflammatory drug (NSAID).
CSN24305 Sulindac Sulfone 59973-80-7 Sulindac sulfone inhibited K-ras-dependent COX-2 protein expression, which resulted in a decrease in prostaglandin synthase E2 production.
CSN12016 Sulindac   38194-50-2 Sulindac is a nonsteroidal anti-inflammatory drug (NSAID) and is thought to act on enzymes COX-1 and COX-2, inhibiting prostaglandin synthesis.
CSN20354 SC-560 188817-13-2 SC-560 is a highly selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 0.009 and 6.3 M for COX-1 and COX-2 respectively). It inhibits COX-1-derived platelet thromboxane B2, gastric PGE2 and dermal PDE2 production and significantly reduces ovarian surface epithelial tumor growth in vivo.
CSN11226 Propyphenazone 479-92-5 Propyphenazone is a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, Propyphenazone-based analogues as prodrugs and selective cyclooxygenase-2 inhibitors.
CSN12646 Piroxicam   36322-90-4 Piroxicam is a selective COX1 inhibitor with anti-inflammatory effects.
CSN13885 Phenacetin   62-44-2 Phenacetin is a non-opioid analgesic used in treatment of pain-relieving and fever-reducing.
CSN12368 Parecoxib Sodium   198470-85-8 Parecoxib Sodium, a water-soluble and injectable prodrug of valdecoxib, is a COX2 inhibitor used for the short-term treatment of postoperative pain in adults.
CSN13805 Parecoxib   198470-84-7 Parecoxib is a potent and selective COX2 inhibitor.
CSN11586 NS-398   123653-11-2 NS-398 is a selective inhibitor of COX2 with IC50s of 75 and 1.77 M for human recombinant COX1 and 2 respectively.
CSN11614 Nimesulide   51803-78-2 Nimesulide is a COX2 selective inhibitor with IC50 of 26 M.
CSN11540 Nepafenac   78281-72-8 Nepafenac is a selective COX2 inhibitor and is prodrug of amfenac used in the treatment of pain and inflammation associated with cataract surgery.
CSN12605 Naproxen   22204-53-1 Naproxen is a COX inhibitor for COX12 with IC50 of 8.7 and 5.2 M, respectively.
CSN11523 Naproxen Sodium 26159-34-2 Naproxen is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 M and 5.2 M, respectively.
CSN21186 Naproxen Etemesil 385800-16-8 Naproxen etemesil is a lipophilic, non-acidic, inactive prodrug of naproxen that is hydrolysed to pharmacologically active Naproxen once absorbed. Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 2.2 and 1.3 gmL, respectively in cell assay.
CSN11503 Nabumetone   42924-53-8 Nabumetone is a non-steroidal anti-inflammatory drug (NSAID) and its active metabolite inhibits the COX.
CSN12893 Meloxicam   71125-38-7 Meloxicam is a nonsteroidal anti-inflammatory agent with selectivity for COX2 (IC50 11.8 M) over COX1 (IC50 143 M) in in vitro assays. It shows potent anti-inflammatory, antipyretic, and analgesic effects with low gastrointestinal toxicity.
CSN11372 Mefenamic Acid   61-68-7 Mefenamic Acid is an inhibitor of COX2 with anti-inflammatory properties, its a non-steroidal anti-inflammatory agent.
CSN11337 Loxoprofen   68767-14-6 Loxoprofen is a non-steroidal anti-inflammatory drug (NSAID) and propionic acid derivative.
CSN11332 Lornoxicam   70374-39-9 Lornoxicam is a COX inhibitor with IC50 of 5 nM and 8 nM for COX1 and 2 respectively. Its a non-steroidal anti-inflammatory drug (NSAID) used in the treatment of various types of pain.
CSN15928 Licofelone 156897-06-2 Licofelone is a dual COXLOX inhibitor being considered as a treatment for osteoarthritis.
CSN11253 Ketorolac Tromethamine 74103-07-4 Ketorolac is a non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 M and 3.50 M, respectively.
CSN11203 Indomethacin Farnesil 85801-02-1 Indometacin farnesil is a prodrug of the non-steroidal anti-inflammatory drug indometacin.
CSN10177 Ibuprofen Lysine   57469-77-9 Ibuprofen lysine is a non-steroidal anti-inflammatory drug (NSAID).
CSN11122 Guacetisal   55482-89-8 Guacetisal is a drug that has been used to treat inflammatory respiratory diseases.
CSN11030 Flunixin Meglumine   42461-84-7 Flunixin meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity.
CSN12744 Flufenamic Acid   530-78-9 Flufenamic Acid is a COX inhibitor and prevents formation of prostaglandins, binds to and reduce the activity of prostaglandin F synthase and activate TRPC6, it is a NSAID drug.
CSN12948 Firocoxib   189954-96-9 Firocoxib is a potent and selective COX2 inhibitor with IC50 of 0.13 M.
CSN11003 Fenoprofen Calcium   34597-40-5 Fenoprofen Calcium is COX-12 inhibitor used as an NSAID. It can also inhibit fatty acid oxidation and acts as a peroxisome proliferator.
CSN10999 Fenbufen   36330-85-5 Fenbufen is a phenylalkanoic derivative with anti-inflammatory, analgesic and antipyretic activity. It is a non-steroidal anti-inflammatory drug.
CSN10969 Etoricoxib   202409-33-4 Etoricoxib is a selective COX2 inhibitor with IC50 of 1.1 0.1 M and 116 8 M for COX1.
CSN10964 Etodolac   41340-25-4 Etodolac is a non-selective inhibitor of COX with IC50 of 53.5 nM, it is a non-steroidal anti-inflammatory compound.
CSN10793 Diclofenac Diethylamine   78213-16-8 Diclofenac diethylamine is a non-selective COX inhibitor used as a nonsteroidal anti-inflammatory drug (NSAID).
CSN10773 Deracoxib   169590-41-4 Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).
CSN10595 Celecoxib   169590-42-5 Celecoxib is a selective COX-2 inhibitor with IC50 of 40 nM.
CSN10518 Butibufen 55837-18-8 Butibufen, is a cyclooxygenase inhibitor used to treat inflammatory and rheumatic disorders.
CSN10503 Bufexamac   2438-72-4 Bufexamac is a COX inhibitor used as an anti-inflammatory agent.
CSN10398 Benorylate   5003-48-5 Benorylate hydrochloride is an ester-linked codrug of aspirin with paracetamol, used as an anti-inflammatory and antipyretic medication.
CSN15857 ATB-346 1226895-20-0 ATB-346 is a hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.
CSN10302 Ampiroxicam 99464-64-9 Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.
CSN10286 Aminoprofen 82821-47-4 Aminoprofen is NSAID (non-steroidal anti-inflammatory drug) and non selective COX inhibitor. Aminoprofen is used to relieve mild to moderate pain.
CSN10202 Acemetacin   53164-05-9 Acemetacin is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.
CSN10201 Aceclofenac   89796-99-6 Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of diclofenac.
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