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Complement System

Complement System

Cat. No. Product Name CAS No. Information
CSN21412 PMX 205 Trifluoroacetate N/A PMX 205 Trifluoroacetate is a potent complement C5a receptor (C5aR CD88) antagonist.
CSN25566 Danicopan 1903768-17-1 Danicopan is selective and orally active small-molecule factor D inhibitor, shows high binding affinity to human Factor D with Kd value of 0.54 nM. It has potential to block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS).
CSN18113 BCX 1470 Methanesulfonate 217099-44-0 BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D (IC5096 nM) and C1s (IC501.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.
CSN18112 BCX 1470 217099-43-9 BCX 1470 inhibits the esterolytic activity of factor D (IC5096 nM) and C1s (IC501.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin.
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